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2YBS
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BU of 2ybs by Molmil
JMJD2A COMPLEXED WITH S-2-HYDROXYGLUTARATE AND HISTONE H3K36me3 PEPTIDE (30-41)
分子名称: (2S)-2-HYDROXYPENTANEDIOIC ACID, GLYCEROL, HISTONE H3.1T, ...
著者Chowdhury, R, Schofield, C.J.
登録日2011-03-10
公開日2011-03-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.
EMBO Rep., 12, 2011
2YBP
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BU of 2ybp by Molmil
JMJD2A COMPLEXED WITH R-2-HYDROXYGLUTARATE AND HISTONE H3K36me3 PEPTIDE (30-41)
分子名称: (2R)-2-hydroxypentanedioic acid, GLYCEROL, HISTONE H3.1T, ...
著者Chowdhury, R, McDonough, M.A, Schofield, C.J.
登録日2011-03-09
公開日2011-03-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.
EMBO Rep., 12, 2011
5IN1
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BU of 5in1 by Molmil
Crystal Structure of the MRG701 chromodomain
分子名称: 1,2-ETHANEDIOL, MRG701, SULFATE ION
著者Huang, Y, Liu, Y.
登録日2016-03-07
公開日2017-03-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural studies on MRG701 chromodomain reveal a novel dimerization interface of MRG proteins in green plants
Protein Cell, 7, 2016
4BD3
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BU of 4bd3 by Molmil
Phf19 links methylated lysine 36 of histone H3 to regulation of Polycomb activity
分子名称: HISTONE H3, PHD FINGER PROTEIN 19
著者Lapinaite, A, Simon, B, Carlomagno, T.
登録日2012-10-04
公開日2012-10-31
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Phf19 Links Methylated Lys36 of Histone H3 to Regulation of Polycomb Activity
Nat.Struct.Mol.Biol., 19, 2012
4N4G
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BU of 4n4g by Molmil
Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha
分子名称: PHOSPHATE ION, ZINC ION, Zinc finger MYND domain-containing protein 11
著者Li, Y, Ren, Y, Li, H.
登録日2013-10-08
公開日2014-03-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.947 Å)
主引用文献ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression
Nature, 508, 2014
4N4H
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BU of 4n4h by Molmil
Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha in complex with histone H3.1K36me3
分子名称: DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Peptide from Histone H3.1, ...
著者Li, Y, Ren, Y, Li, H.
登録日2013-10-08
公開日2014-03-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression
Nature, 508, 2014
4N4I
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BU of 4n4i by Molmil
Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha in complex with histone H3.3K36me3
分子名称: DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Peptide from Histone H3.3, ...
著者Li, Y, Ren, Y, Li, H.
登録日2013-10-08
公開日2014-03-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression
Nature, 508, 2014
6S01
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BU of 6s01 by Molmil
Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome
分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ...
著者Wang, H, Farnung, L, Dienemann, C, Cramer, P.
登録日2019-06-13
公開日2019-12-18
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding.
Nat.Struct.Mol.Biol., 27, 2020
4PL6
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BU of 4pl6 by Molmil
Structure of the chromodomain of MRG2 in complex with H3K4me3
分子名称: At1g02740, H3K4me3
著者Liu, Y.C, Huang, Y.
登録日2014-05-16
公開日2015-07-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.681 Å)
主引用文献Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression.
Plos Genet., 10, 2014
2M16
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BU of 2m16 by Molmil
P75/LEDGF PWWP Domain
分子名称: PC4 and SFRS1-interacting protein
著者Crowe, B.L, Foster, M.P.
登録日2012-11-18
公開日2013-02-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes.
Nucleic Acids Res., 41, 2013
7E29
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BU of 7e29 by Molmil
Crystal Structure of Saccharomyces cerevisiae Ioc4 PWWP domain fused with MBP
分子名称: Maltose/maltodextrin-binding periplasmic protein,ISWI one complex protein 4, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Li, J, Smolle, M, Liang, H, Liu, Y.
登録日2021-02-05
公開日2022-02-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function.
Nucleic Acids Res., 50, 2022
8IFG
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BU of 8ifg by Molmil
Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe
分子名称: Chromatin modification-related protein eaf3, Cph1, Cph2, ...
著者Zhang, H.Q, Wang, X, Wang, Y.N, Liu, S.M, Zhang, Y, Xu, K, Ji, L.T, Kornberg, R.D.
登録日2023-02-17
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Class I histone deacetylase complex: Structure and functional correlates.
Proc Natl Acad Sci U S A, 120, 2023
8CBQ
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BU of 8cbq by Molmil
structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome
分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ...
著者Koutna, E, Kouba, T, Novacek, J, Veverka, V.
登録日2023-01-25
公開日2023-09-06
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
8CBN
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BU of 8cbn by Molmil
structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome
分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ...
著者Koutna, E, Kouba, T, Novacek, J, Veverka, V.
登録日2023-01-25
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
8HXY
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BU of 8hxy by Molmil
Cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome
分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
著者Cui, H, Wang, H.
登録日2023-01-05
公開日2023-09-27
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8JHO
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BU of 8jho by Molmil
Cryo-EM structure of the histone deacetylase complex Rpd3S in complex with di-nucleosome
分子名称: Chromatin modification-related protein EAF3, Di-nucleosome template foward, Di-nucleosome template reverse, ...
著者Wang, H.
登録日2023-05-25
公開日2023-09-27
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8HXZ
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BU of 8hxz by Molmil
Cryo-EM structure of Eaf3 CHD in complex with nucleosome
分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
著者Cui, H, Wang, H.
登録日2023-01-05
公開日2023-09-27
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8HY0
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BU of 8hy0 by Molmil
Composite cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome
分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
著者Cui, H, Wang, H.
登録日2023-01-05
公開日2023-09-27
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8HXX
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BU of 8hxx by Molmil
Cryo-EM structure of the histone deacetylase complex Rpd3S
分子名称: Chromatin modification-related protein EAF3, Histone H3, Histone deacetylase RPD3, ...
著者Cui, H, Wang, H.
登録日2023-01-05
公開日2023-09-27
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
4HON
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BU of 4hon by Molmil
Crystal structure of human JMJD2D/KDM4D in complex with an H3K9me3 peptide and 2-oxoglutarate
分子名称: 1,3-PROPANDIOL, 2-OXOGLUTARIC ACID, Histone H3 Peptide, ...
著者Krishnan, S, Trievel, R.C.
登録日2012-10-22
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases.
Structure, 21, 2013
4HOO
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BU of 4hoo by Molmil
Crystal structure of human JMJD2D/KDM4D apoenzyme
分子名称: ACETATE ION, Lysine-specific demethylase 4D, NICKEL (II) ION, ...
著者Krishnan, S, Trievel, R.C.
登録日2012-10-22
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.495 Å)
主引用文献Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases.
Structure, 21, 2013
4A7J
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BU of 4a7j by Molmil
Symmetric Dimethylation of H3 Arginine 2 is a Novel Histone Mark that Supports Euchromatin Maintenance
分子名称: HISTONE H3.1T, WD REPEAT-CONTAINING PROTEIN 5
著者Migliori, V, Muller, J, Phalke, S, Low, D, Bezzi, M, ChuenMok, W, Gunaratne, J, Capasso, P, Bassi, C, Cecatiello, V, DeMarco, A, Blackstock, W, Kuznetsov, V, Amati, B, Mapelli, M, Guccione, E.
登録日2011-11-14
公開日2012-01-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Symmetric Dimethylation of H3R2 is a Newly Identified Histone Mark that Supports Euchromatin Maintenance
Nat.Struct.Mol.Biol., 19, 2012
4AI9
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BU of 4ai9 by Molmil
JMJD2A Complexed with Daminozide
分子名称: CHLORIDE ION, DAMINOZIDE, GLYCEROL, ...
著者Chowdhury, R, Schofield, C.J.
登録日2012-02-08
公開日2012-10-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.
J. Med. Chem., 55, 2012
6WAU
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BU of 6wau by Molmil
Complex structure of PHF19
分子名称: Histone H3.1t peptide, PHD finger protein 19, UNKNOWN ATOM OR ION
著者Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC)
登録日2020-03-26
公開日2020-08-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19.
Elife, 9, 2020
6WAT
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BU of 6wat by Molmil
complex structure of PHF1
分子名称: Histone H3.1t peptide, PHD finger protein 1, UNKNOWN ATOM OR ION
著者Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC)
登録日2020-03-26
公開日2020-08-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19.
Elife, 9, 2020

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