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3NK9
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Crystal structure of Staphylococcal nuclease variant Delta+PHS V74A at cryogenic temperature
分子名称: CALCIUM ION, Nuclease A, THYMIDINE-3',5'-DIPHOSPHATE
著者Caro, J.A, Schlessman, J.L, Garcia-Moreno E, B, Heroux, A.
登録日2010-06-18
公開日2011-06-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Cavities determine the pressure unfolding of proteins.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F7O
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BU of 4f7o by Molmil
Crystal structure of CSN5
分子名称: COP9 signalosome complex subunit 5, THIOCYANATE ION, ZINC ION
著者Echalier, A, Birol, M, Hoh, F, Dumas, C.
登録日2012-05-16
公開日2013-01-23
最終更新日2013-02-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4F7X
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Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A/L25A at cryogenic temperature
分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
著者Caro, J.A, Clark, I, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B.
登録日2012-05-16
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Pressure effects in proteins
To be Published
3PRL
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BU of 3prl by Molmil
Crystal structure of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Bacillus halodurans C-125
分子名称: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, SULFATE ION
著者Malashkevich, V.N, Toro, R, Seidel, R, Garrett, S, Foti, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2010-11-29
公開日2010-12-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Bacillus halodurans C-125
To be Published
4EZL
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BU of 4ezl by Molmil
Potent and Selective Inhibitors of PI3K-delta: Obtaining Isoform Selectivity from the Affinity Pocket and Tryptophan Shelf
分子名称: 2-(1-{[2-(2-aminopyrimidin-5-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者Murray, J.M.
登録日2012-05-02
公開日2013-04-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Potent and selective inhibitors of PI3K-delta: obtaining isoform selectivity from the affinity pocket and tryptophan shelf
Bioorg.Med.Chem.Lett., 22, 2012
4F1C
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Human Insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
登録日2012-05-06
公開日2013-05-08
最終更新日2013-12-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4F2C
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The Crystal Structure of a Human MitoNEET double mutant in which Gly 66 are Asp 67 are both Replaced with Ala Residues
分子名称: CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER
著者Baxter, E.L, Zuris, J.A, Wang, C, Axelrod, H.L, Cohen, A.E, Paddock, M.L, Nechushtai, R, Onuchic, J.N, Jennings, P.A.
登録日2012-05-07
公開日2012-12-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Allosteric control in a metalloprotein dramatically alters function.
Proc.Natl.Acad.Sci.USA, 110, 2013
3Q3Y
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BU of 3q3y by Molmil
Complex structure of HEVB EV93 main protease 3C with Compound 1 (AG7404)
分子名称: 1,2-ETHANEDIOL, AMMONIUM ION, HEVB EV93 3C protease, ...
著者Costenaro, L, Kaczmarska, Z, Arnan, C, Sola, M, Coutard, B, Norder, H, Canard, B, Coll, M.
登録日2010-12-22
公開日2011-09-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93.
J.Virol., 85, 2011
3PIU
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BU of 3piu by Molmil
High-resolution structure of native Malus domestica ACC synthase
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 1-aminocyclopropane-1-carboxylate synthase
著者Scharer, M.A, Grutter, M.G, Capitani, G.
登録日2010-11-08
公開日2010-12-15
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural basis for reduced activity of 1-aminocyclopropane-1-carboxylate synthase affected by a mutation linked to andromonoecy.
Febs Lett., 585, 2011
4F1B
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BU of 4f1b by Molmil
Human Insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
登録日2012-05-06
公開日2013-05-08
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.591 Å)
主引用文献Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4F1G
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Human insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
登録日2012-05-06
公開日2013-05-08
最終更新日2013-12-18
実験手法X-RAY DIFFRACTION (1.637 Å)
主引用文献Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
3Q27
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BU of 3q27 by Molmil
Cyrstal structure of human alpha-synuclein (32-57) fused to maltose binding protein (MBP)
分子名称: GLYCEROL, Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, ...
著者Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2010-12-19
公開日2011-06-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.302 Å)
主引用文献Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20, 2011
4F6E
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BU of 4f6e by Molmil
Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MANGANESE (II) ION, ...
著者Sheng, Y, Cascio, D, Valentine, J.S.
登録日2012-05-14
公開日2013-06-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae
to be published
4FAO
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Specificity and Structure of a high affinity Activin-like 1 (ALK1) signaling complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B, Growth/differentiation factor 2, ...
著者Townson, S.A, Martinez-Hackert, E, Greppi, C, Lowden, P, Sako, D, Liu, J, Ucran, J.A, Liharska, K, Underwood, K.W, Seehra, J, Kumar, R, Grinberg, A.V.
登録日2012-05-22
公開日2012-06-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.357 Å)
主引用文献Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex.
J.Biol.Chem., 287, 2012
4FQW
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Crystal Structure of AAAA+UDP+Gal at pH 5.0 with MPD as the cryoprotectant
分子名称: Histo-blood group ABO system transferase, TETRAETHYLENE GLYCOL, URIDINE-5'-DIPHOSPHATE, ...
著者Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V.
登録日2012-06-25
公開日2013-12-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state.
Glycobiology, 24, 2014
4FRD
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Crystal Structure of ABBA+UDP+Gal at pH 9.0 with MPD as the cryoprotectant
分子名称: Histo-blood group ABO system transferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
著者Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V.
登録日2012-06-26
公開日2013-12-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state.
Glycobiology, 24, 2014
4FN3
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BU of 4fn3 by Molmil
Crystal Structure of an S52A mutant of the Restriction-Modification Controller Protein C.Esp1396I
分子名称: Regulatory protein, SULFATE ION
著者Martin, R.N.A, McGeehan, J.E, Kneale, G.G.
登録日2012-06-19
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I.
Plos One, 9, 2014
4FQT
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Structure of AgamOBP1 Bound to 6-methyl-5-hepten-2-one
分子名称: 6-methylhept-5-en-2-one, Anopheles Gambiae Odorant Binding protein 1, TETRAETHYLENE GLYCOL
著者Murphy, E.J, Booth, J.C.
登録日2012-06-25
公開日2013-01-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Interactions of Anopheles gambiae Odorant-binding Proteins with a Human-derived Repellent: IMPLICATIONS FOR THE MODE OF ACTION OF N,N-DIETHYL-3-METHYLBENZAMIDE (DEET).
J.Biol.Chem., 288, 2013
4FRB
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Crystal Structure of ABBA+UDP+Gal at pH 8.0 with MPD as the cryoprotectant
分子名称: Histo-blood group ABO system transferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
著者Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V.
登録日2012-06-26
公開日2013-12-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state.
Glycobiology, 24, 2014
4FAJ
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BU of 4faj by Molmil
Structure and mode of peptide binding of pheromone receptor PrgZ
分子名称: GLYCEROL, PrgZ, Sex pheromone cCF10, ...
著者Berntsson, R.P.-A, Schuurman-Wolters, G.K, Dunny, K, Slotboom, D.J, Poolman, B.
登録日2012-05-22
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and Mode of Peptide Binding of Pheromone Receptor PrgZ.
J.Biol.Chem., 287, 2012
3OAJ
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CRYSTAL STRUCTURE OF putative dioxygenase from Bacillus subtilis subsp. subtilis str. 168
分子名称: Putative ring-cleaving dioxygenase mhqO, SULFATE ION, ZINC ION
著者Malashkevich, V.N, Toro, R, Seidel, R, Garrett, S, Foti, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2010-08-05
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献CRYSTAL STRUCTURE OF putative dioxygenase from Bacillus subtilis subsp. subtilis str. 168
To be Published
3OCF
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Crystal structure of fumarate lyase:delta crystallin from Brucella melitensis in native form
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Fumarate lyase:Delta crystallin
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-08-09
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of fumarate lyase:delta crystallin from Brucella melitensis in native form
To be Published
3OGB
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Sperm whale myoglobin mutant H64W deoxy-form
分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Birukou, I, Soman, J, Olson, J.S.
登録日2010-08-16
公開日2010-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Blocking the gate to ligand entry in human hemoglobin.
J.Biol.Chem., 286, 2011
3QMC
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Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1
分子名称: 5'-D(*GP*CP*CP*AP*CP*CP*GP*CP*TP*GP*GP*C)-3', 5'-D(*GP*CP*CP*AP*GP*CP*GP*GP*TP*GP*GP*C)-3', CpG-binding protein, ...
著者Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2011-02-04
公開日2011-02-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3QIV
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Crystal structure of a putative short-chain dehydrogenase or 3-oxoacyl-[acyl-carrier-protein] reductase from Mycobacterium paratuberculosis ATCC BAA-968 / K-10
分子名称: short-chain dehydrogenase or 3-oxoacyl-[acyl-carrier-protein] reductase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-01-27
公開日2011-02-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015

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件を2024-07-17に公開中

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