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2PGT
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE S-TRANSFERASE P1-1[V104] COMPLEXED WITH (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE
分子名称: (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE, ...
著者Ji, X.
登録日1997-02-17
公開日1997-09-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and function of the xenobiotic substrate-binding site and location of a potential non-substrate-binding site in a class pi glutathione S-transferase.
Biochemistry, 36, 1997
2PGV
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GTB C209A
分子名称: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MERCURY (II) ION
著者Letts, J.A, Schuman, B.
登録日2007-04-10
公開日2007-07-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献The effect of heavy atoms on the conformation of the active-site polypeptide loop in human ABO(H) blood-group glycosyltransferase B.
Acta Crystallogr.,Sect.D, 63, 2007
2PGW
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Crystal structure of a putative muconate cycloisomerase from Sinorhizobium meliloti 1021
分子名称: GLYCEROL, Muconate cycloisomerase
著者Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-04-10
公開日2007-04-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of a putative muconate cycloisomerase from Sinorhizobium meliloti 1021
To be Published
2PGX
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Crystal structure of UPF0341 protein yhiQ from E. coli, Northeast Structural Genomics Target ER585
分子名称: UPF0341 protein yhiQ
著者Forouhar, F, Su, M, Seetharaman, J, Janjua, H, Fang, Y, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2007-04-10
公開日2007-04-24
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of UPF0341 protein yhiQ from Escherichia coli.
To be Published
2PGY
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GTB C209A, no Hg
分子名称: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase
著者Letts, J.A, Schuman, B.
登録日2007-04-10
公開日2007-07-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献The effect of heavy atoms on the conformation of the active-site polypeptide loop in human ABO(H) blood-group glycosyltransferase B.
Acta Crystallogr.,Sect.D, 63, 2007
2PGZ
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Crystal structure of Cocaine bound to an ACh-Binding Protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COCAINE, Soluble acetylcholine receptor, ...
著者Hansen, S.B, Taylor, P.
登録日2007-04-10
公開日2007-07-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors.
J.Mol.Biol., 369, 2007
2PH0
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Crystal structure of the Q6D2T7_ERWCT protein from Erwinia carotovora. NESG target EwR41.
分子名称: Uncharacterized protein
著者Vorobiev, S.M, Neely, H, Seetharaman, J, Chen, C.-X, Cunningham, K, Ma, L.-C, Owens, L, Fang, Y, Xiao, R, Acton, T, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2007-04-10
公開日2007-04-24
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the Q6D2T7_ERWCT protein from Erwinia carotovora.
To be Published
2PH1
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Crystal structure of nucleotide-binding protein AF2382 from Archaeoglobus fulgidus, Northeast Structural Genomics Target GR165
分子名称: Nucleotide-binding protein, ZINC ION
著者Forouhar, F, Abashidze, M, Seetharaman, J, Janjua, H, Fang, Y, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2007-04-10
公開日2007-04-24
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of nucleotide-binding protein AF2382 from Archaeoglobus fulgidus.
To be Published
2PH3
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Crystal structure of 3-oxoacyl-[acyl carrier protein] reductase TTHA0415 from Thermus thermophilus
分子名称: 3-oxoacyl-[acyl carrier protein] reductase
著者Swindell II, J.T, Chen, L, Zhu, J, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Fu, Z.-Q, Chrzas, J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-10
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of 3-oxoacyl-[acyl carrier protein] reductase TTHA0415 from Thermus thermophilus
To be Published
2PH4
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Crystal structure of a novel Arg49 phospholipase A2 homologue from Zhaoermia mangshanensis venom
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, Zhaoermiatoxin
著者Murakami, M.T, Kuch, U, Mebs, D, Arni, R.K.
登録日2007-04-10
公開日2008-03-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of a novel myotoxic Arg49 phospholipase A(2) homolog (zhaoermiatoxin) from Zhaoermia mangshanensis snake venom: Insights into Arg49 coordination and the role of Lys122 in the polarization of the C-terminus.
Toxicon, 51, 2008
2PH5
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Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54
分子名称: Homospermidine synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
著者Forouhar, F, Hussain, M, Seetharaman, J, Fang, Y, Janjua, H, Xiao, R, Cunningham, K, Ma, L.-C, Owens, L, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2007-04-10
公開日2007-05-15
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD.
To be Published
2PH6
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Crystal Structure of Human Beta Secretase Complexed with inhibitor
分子名称: 3-({[(1R)-1-(4-FLUOROPHENYL)ETHYL]AMINO}CARBONYL)-5-[METHYL(METHYLSULFONYL)AMINO]BENZYL ALPHA-METHYL-D-PHENYLALANINATE, Beta-secretase 1, SULFATE ION
著者Munshi, S.
登録日2007-04-10
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2PH7
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Crystal structure of AF2093 from Archaeoglobus fulgidus
分子名称: Uncharacterized protein AF_2093
著者Chang, J.C, Yang, H, Hwang, J, Zhu, J, Chen, L, Fu, Z.-Q, Xu, H, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2007-04-10
公開日2007-05-08
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of AF2093 from Archaeoglobus fulgidus.
To be Published
2PH8
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Crystal Structure of Human Beta Secretase Complexed with inhibitor
分子名称: Beta-secretase 1, N-[(5R,14R)-5-AMINO-5,14-DIMETHYL-4-OXO-3-OXA-18-AZATRICYCLO[15.3.1.1~7,11~]DOCOSA-1(21),7(22),8,10,17,19-HEXAEN-19-YL]-N-METHYLMETHANESULFONAMIDE, SULFATE ION
著者Munshi, S.
登録日2007-04-10
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2PH9
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Galanthamine bound to an ACh-binding Protein
分子名称: (-)-GALANTHAMINE, Soluble acetylcholine receptor, TETRAETHYLENE GLYCOL
著者Hansen, S.B, Taylor, P.
登録日2007-04-10
公開日2007-07-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors.
J.Mol.Biol., 369, 2007
2PHA
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Crystal structure of native, unliganded human arginase at 1.90 resolution
分子名称: Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Pique, M.E, Christianson, D.W.
登録日2007-04-10
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster.
J.Am.Chem.Soc., 129, 2007
2PHB
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An Orally Efficacious Factor Xa Inhibitor
分子名称: (2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[2-FLUORO-4-(2-OXOPYRIDIN-1(2H)-YL)PHENYL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE, CALCIUM ION, Coagulation factor X, ...
著者Zhang, E, Kohrt, J.T, Bigge, C.F, Finzel, B.C.
登録日2007-04-10
公開日2008-03-25
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an orally efficacious factor Xa inhibitor
Chem.Biol.Drug Des., 70, 2007
2PHC
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Crystal structure of conserved uncharacterized protein PH0987 from Pyrococcus horikoshii
分子名称: Uncharacterized protein PH0987
著者Swindell II, J.T, Chen, L, Zhu, J, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Fu, Z.-Q, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-10
公開日2007-05-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Crystal structure of conserved uncharacterized protein PH0987 from Pyrococcus horikoshii.
To be Published
2PHD
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Crystal Structure Determination of a Salicylate 1,2-Dioxygenase from Pseudaminobacter salicylatoxidans
分子名称: ACETATE ION, CHLORIDE ION, FE (III) ION, ...
著者Matera, I, Ferraroni, M, Briganti, F.
登録日2007-04-11
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure Determination of a Salicylate 1,2-Dioxygenase from Pseudaminobacter salicylatoxidans
To be Published
2PHE
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Model for VP16 binding to PC4
分子名称: Alpha trans-inducing protein, TRANSCRIPTIONAL COACTIVATOR PC4
著者Jonker, H.R.A, Wechselberger, R.W, Boelens, R, Folkers, G.E, Kaptein, R.
登録日2007-04-11
公開日2007-04-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Properties of the Promiscuous VP16 Activation Domain
Biochemistry, 44, 2005
2PHF
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Pterocarpus angolensis lectin complexed with Man-6
分子名称: CALCIUM ION, Lectin, MANGANESE (II) ION, ...
著者Garcia-Pino, A, Buts, L, Wyns, L, Imberty, A, Loris, R.
登録日2007-04-11
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献How a plant lectin recognizes high mannose oligosaccharides
Plant Physiol., 144, 2007
2PHG
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Model for VP16 binding to TFIIB
分子名称: Alpha trans-inducing protein, Transcription initiation factor IIB
著者Jonker, H.R.A, Wechselberger, R.W, Boelens, R, Folkers, G.E, Kaptein, R.
登録日2007-04-11
公開日2007-04-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Properties of the Promiscuous VP16 Activation Domain
Biochemistry, 44, 2005
2PHH
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THE COENZYME ANALOGUE ADENOSINE 5-DIPHOSPHORIBOSE DISPLACES FAD IN THE ACTIVE SITE OF P-HYDROXYBENZOATE HYDROXYLASE. AN X-RAY CRYSTALLOGRAPHIC INVESTIGATION
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID
著者Van Derlaan, J.M, Drenth, J, Hol, W.G.J.
登録日1989-06-19
公開日1990-10-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The coenzyme analogue adenosine 5-diphosphoribose displaces FAD in the active site of p-hydroxybenzoate hydroxylase. An x-ray crystallographic investigation.
Biochemistry, 28, 1989
2PHI
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A LARGE CONFORMATIONAL CHANGE IS FOUND IN THE CRYSTAL STRUCTURE OF THE PORCINE PANCREATIC PHOSPHOLIPASE A2 POINT MUTANT F63V
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Dijkstra, B.W, Thunnissen, M.M.G.M, Kalk, K.H, Drenth, J.
登録日1993-04-08
公開日1993-07-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a porcine pancreatic phospholipase A2 mutant. A large conformational change caused by the F63V point mutation.
J.Mol.Biol., 232, 1993
2PHK
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THE CRYSTAL STRUCTURE OF A PHOSPHORYLASE KINASE PEPTIDE SUBSTRATE COMPLEX: KINASE SUBSTRATE RECOGNITION
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ...
著者Lowe, E.D, Noble, M.E.M, Skamnaki, V.T, Oikonomakos, N.G, Owen, D.J, Johnson, L.N.
登録日1998-06-18
公開日1999-01-13
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition.
EMBO J., 16, 1997

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