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2P4G
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CRYSTAL STRUCTURE OF A PYRIMIDINE REDUCTASE-LIKE PROTEIN (DIP1392) FROM CORYNEBACTERIUM DIPHTHERIAE NCTC AT 2.30 A RESOLUTION
分子名称: 1,2-ETHANEDIOL, Hypothetical protein, NITRATE ION
著者Joint Center for Structural Genomics (JCSG)
登録日2007-03-12
公開日2007-03-27
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of hypothetical protein (NP_939744.1) from Corynebacterium diphtheriae at 2.30 A resolution
To be published
2P4H
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Crystal Structure of Vestitone Reductase from Alfalfa (Medicago sativa L.)
分子名称: Vestitone reductase
著者Wang, X, Shao, H, Dixon, R.A.
登録日2007-03-12
公開日2007-05-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal Structure of Vestitone Reductase from Alfalfa (Medicago sativa L.).
J.Mol.Biol., 369, 2007
2P4I
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Evolution of a highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor
分子名称: 4-METHYL-3-({3-[2-(METHYLAMINO)PYRIMIDIN-4-YL]PYRIDIN-2-YL}OXY)-N-[2-MORPHOLIN-4-YL-5-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE, Angiopoietin-1 receptor
著者Bellon, S.F.
登録日2007-03-12
公開日2007-03-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor.
J.Med.Chem., 50, 2007
2P4J
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Crystal structure of beta-secretase bond to an inhibitor with Isophthalamide Derivatives at P2-P3
分子名称: Beta-secretase 1, N-[(1S,2S,4R)-2-HYDROXY-1-ISOBUTYL-5-({(1S)-1-[(ISOPROPYLAMINO)CARBONYL]-2-METHYLPROPYL}AMINO)-4-METHYL-5-OXOPENTYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N'-[(1R)-1-PHENYLETHYL]ISOPHTHALAMIDE
著者Hong, L, Ghosh, A.K, Tang, J.
登録日2007-03-12
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands.
J.Med.Chem., 50, 2007
2P4K
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Contribution to Structure and Catalysis of Tyrosine 34 in Human Manganese Superoxide Dismutase
分子名称: MANGANESE (II) ION, Superoxide dismutase
著者Perry, J.J.
登録日2007-03-12
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis.
Biochemistry, 48, 2009
2P4L
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Structure and sodium channel activity of an excitatory I1-superfamily conotoxin
分子名称: I-superfamily conotoxin r11a
著者Buczek, O, Wei, D.X, Babon, J.J, Yang, X.D, Fiedler, B, Yoshikami, D, Olivera, B.M, Bulaj, G, Norton, R.S.
登録日2007-03-12
公開日2007-09-25
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structure and Sodium Channel Activity of an Excitatory I(1)-Superfamily Conotoxin
Biochemistry, 46, 2007
2P4M
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High pH structure of Rtms5 H146S variant
分子名称: GFP-like non-fluorescent chromoprotein, IODIDE ION
著者Battad, J.M, Wilmann, P.G, Olsen, S, Byres, E, Smith, S.C, Dove, S.G, Turcic, K.N, Devenish, R.J, Rossjohn, J, Prescott, M.
登録日2007-03-12
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structural basis for the pH-dependent increase in fluorescence efficiency of chromoproteins
J.Mol.Biol., 368, 2007
2P4N
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Human Monomeric Kinesin (1BG2) and Bovine Tubulin (1JFF) Docked into the 9-Angstrom Cryo-EM Map of Nucleotide-Free Kinesin Complexed to the Microtubule
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Sindelar, C.V, Downing, K.H.
登録日2007-03-12
公開日2008-07-08
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献The beginning of kinesin's force-generating cycle visualized at 9-A resolution.
J.Cell Biol., 177, 2007
2P4O
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CRYSTAL STRUCTURE OF A PUTATIVE LACTONASE OF THE SMP-30/GLUCONOLACTONASE/LRE-LIKE REGION FAMILY (NPUN_F0524) FROM NOSTOC PUNCTIFORME PCC 73102 AT 1.90 A RESOLUTION
分子名称: ACETATE ION, GLYCEROL, hypothetical protein
著者Joint Center for Structural Genomics (JCSG)
登録日2007-03-12
公開日2007-04-17
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of hypothetical protein (ZP_00111901.1) from Nostoc punctiforme PCC 73102 at 1.90 A resolution
To be published
2P4P
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Crystal structure of a CorC_HlyC domain from Haemophilus ducreyi
分子名称: CALCIUM ION, GLYCEROL, Hypothetical protein HD1797, ...
著者Cuff, M.E, Volkart, L, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-03-12
公開日2007-05-22
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of a CorC_HlyC domain from Haemophilus ducreyi
To be Published
2P4Q
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Crystal Structure Analysis of Gnd1 in Saccharomyces cerevisiae
分子名称: 6-phosphogluconate dehydrogenase, decarboxylating 1, CITRATE ANION
著者He, W, Wang, Y, Liu, W, Zhou, C.Z.
登録日2007-03-12
公開日2007-07-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1
Bmc Struct.Biol., 7, 2007
2P4R
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Structural basis for a novel interaction between AIP4 and beta-PIX
分子名称: E3 ubiquitin-protein ligase Itchy homolog, GLYCEROL, Rho guanine nucleotide exchange factor 7, ...
著者Min, K.C.
登録日2007-03-13
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献A novel interaction between atrophin-interacting protein 4 and beta-p21-activated kinase-interactive exchange factor is mediated by an SH3 domain.
J.Biol.Chem., 282, 2007
2P4S
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Structure of Purine Nucleoside Phosphorylase from Anopheles gambiae in complex with DADMe-ImmH
分子名称: 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L.
登録日2007-03-13
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.
Biochemistry, 46, 2007
2P4T
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Structure of the Q67H mutant of R67 dihydrofolate reductase-NADP+ complex reveals a novel cofactor binding mode
分子名称: Dihydrofolate reductase type 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Divya, N, Grifith, E, Narayana, N.
登録日2007-03-13
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structure of the Q67H mutant of R67 dihydrofolate reductase-NADP+ complex reveals a novel cofactor binding mode.
Protein Sci., 16, 2007
2P4U
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Crystal structure of acid phosphatase 1 (Acp1) from Mus musculus
分子名称: Acid phosphatase 1, PHOSPHATE ION
著者Bonanno, J.B, Freeman, J, Bain, K.T, Wu, B, Xu, W, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-03-13
公開日2007-03-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
2P4V
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Crystal structure of the transcript cleavage factor, GreB at 2.6A resolution
分子名称: Transcription elongation factor greB
著者Vassylyeva, M.N, Svetlov, V, Dearborn, A.D, Klyuyev, S, Artsimovitch, I, Vassylyev, D.G.
登録日2007-03-13
公開日2008-01-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The carboxy-terminal coiled-coil of the RNA polymerase beta'-subunit is the main binding site for Gre factors.
Embo Rep., 8, 2007
2P4W
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Crystal structure of heat shock regulator from Pyrococcus furiosus
分子名称: SULFATE ION, Transcriptional regulatory protein arsR family
著者Liu, W, Vierke, G, Panjikar, S, Thomm, M, Ladenstein, R.
登録日2007-03-13
公開日2007-03-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the Archaeal Heat Shock Regulator from Pyrococcus furiosus: A Molecular Chimera Representing Eukaryal and Bacterial Features.
J.Mol.Biol., 369, 2007
2P4X
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Crystal Structure of Atp12 from Paracoccus Denitrificans
分子名称: ATP12 ATPase
著者Ludlam, A.V, Brunzelle, J.S, Gatti, D.L, Ackerman, S.H.
登録日2007-03-13
公開日2008-03-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Atp12 from Paracoccus Denitrificans
To be Published
2P4Y
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Crystal structure of human PPAR-gamma-ligand binding domain complexed with an indole-based modulator
分子名称: (2R)-2-(4-CHLORO-3-{[3-(6-METHOXY-1,2-BENZISOXAZOL-3-YL)-2-METHYL-6-(TRIFLUOROMETHOXY)-1H-INDOL-1-YL]METHYL}PHENOXY)PROPANOIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Peroxisome proliferator-activated receptor gamma
著者McKeever, B.M.
登録日2007-03-13
公開日2008-01-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The differential interactions of peroxisome proliferator-activated receptor gamma ligands with Tyr473 is a physical basis for their unique biological activities.
Mol.Pharmacol., 73, 2008
2P4Z
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A Ferredoxin-like Metallo-beta-lactamase Superfamily Protein from Thermoanaerobacter tengcongensis
分子名称: FE (III) ION, Metal-dependent hydrolases of the beta-lactamase superfamily II
著者Liang, D.-C, Gu, S.-Y.
登録日2007-03-14
公開日2008-03-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Tflp: A ferredoxin-like metallo-beta-lactamase superfamily protein from Thermoanaerobacter tengcongensis
Proteins, 72, 2008
2P50
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Crystal structure of N-acetyl-D-Glucosamine-6-Phosphate deacetylase liganded with Zn
分子名称: N-acetylglucosamine-6-phosphate deacetylase, ZINC ION
著者Fedorov, A.A, Fedorov, E.V, Hall, R.S, Raushel, F.M, Almo, S.C.
登録日2007-03-14
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-d-glucosamine-6-phosphate Deacetylase.
Biochemistry, 46, 2007
2P51
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Crystal structure of the S. pombe Pop2p deadenylation subunit
分子名称: MAGNESIUM ION, SPCC18.06c protein
著者Thyssen Jonstrup, A, Andersen, K.R, Van, L.B, Brodersen, D.E.
登録日2007-03-14
公開日2007-05-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The 1.4-A crystal structure of the S. pombe Pop2p deadenylase subunit unveils the configuration of an active enzyme
Nucleic Acids Res., 35, 2007
2P52
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mouse p53 DNA-binding domain in zinc-free oxidized state
分子名称: Cellular tumor antigen p53
著者Kwon, E, Kim, D.Y, Suh, S.W, Kim, K.K.
登録日2007-03-14
公開日2008-01-29
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the mouse p53 core domain in zinc-free state.
Proteins, 70, 2008
2P53
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Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase D273N mutant complexed with N-acetyl phosphonamidate-d-glucosamine-6-phosphate
分子名称: 2-deoxy-2-{[(S)-hydroxy(methyl)phosphoryl]amino}-6-O-phosphono-alpha-D-glucopyranose, N-acetylglucosamine-6-phosphate deacetylase, ZINC ION
著者Fedorov, A.A, Fedorov, E.V, Hall, R.S, Raushel, F.M, Almo, S.C.
登録日2007-03-14
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-d-glucosamine-6-phosphate Deacetylase.
Biochemistry, 46, 2007
2P54
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a crystal structure of PPAR alpha bound with SRC1 peptide and GW735
分子名称: 2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor alpha
著者Xu, R.X, Xu, H.E, Sierra, M.L, Montana, V.G, Lambert, M.H, Pianetti, P.M.
登録日2007-03-14
公開日2007-04-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Substituted 2-[(4-Aminomethyl)phenoxy]-2-methylpropionic Acid PPAR Agonists. 1.Discovery of a Novel Series of Potent HDLc Raising Agents.
J.Med.Chem., 50, 2007

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