PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

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1YVJ	Crystal structure of the Jak3 kinase domain in complex with a staurosporine analogue 分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, Tyrosine-protein kinase JAK3 著者 Boggon, T.J, Li, Y, Manley, P.W, Eck, M.J. 登録日 2005-02-15 公開日 2005-05-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog Blood, 106, 2005
2ACV	Crystal Structure of Medicago truncatula UGT71G1 分子名称: URIDINE-5'-DIPHOSPHATE, triterpene UDP-glucosyl transferase UGT71G1 著者 Shao, H, He, X, Achnine, L, Blount, J.W, Dixon, R.A, Wang, X. 登録日 2005-07-19 公開日 2005-11-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of a Multifunctional Triterpene/Flavonoid Glycosyltransferase from Medicago truncatula. Plant Cell, 17, 2005
2ACW	Crystal Structure of Medicago truncatula UGT71G1 complexed with UDP-glucose 分子名称: URIDINE-5'-DIPHOSPHATE-GLUCOSE, triterpene UDP-glucosyl transferase UGT71G1 著者 Shao, H, He, X, Achnine, L, Blount, J.W, Dixon, R.A, Wang, X. 登録日 2005-07-19 公開日 2005-11-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structures of a Multifunctional Triterpene/Flavonoid Glycosyltransferase from Medicago truncatula. Plant Cell, 17, 2005
2A0I	F Factor TraI Relaxase Domain bound to F oriT Single-stranded DNA 分子名称: F plasmid single-stranded oriT DNA, IMIDAZOLE, MAGNESIUM ION, ... 著者 Larkin, C, Datta, S, Harley, M.J, Anderson, B.J, Ebie, A, Hargreaves, V, Schildbach, J.F. 登録日 2005-06-16 公開日 2005-10-25 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Inter- and intramolecular determinants of the specificity of single-stranded DNA binding and cleavage by the f factor relaxase. Structure, 13, 2005
1YZ3	Structure of human pnmt complexed with cofactor product adohcy and inhibitor SK&F 64139 分子名称: 7,8-DICHLORO-1,2,3,4-TETRAHYDROISOQUINOLINE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Wu, Q, Gee, C.L, Lin, F, Martin, J.L, Grunewald, G.L, McLeish, M.J. 登録日 2005-02-27 公開日 2006-02-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase J.Med.Chem., 48, 2005
2D4J	Transformed monoclinic crystal of hen egg-white lysozyme from a heavy water solution 分子名称: Lysozyme C, NITRATE ION 著者 Harata, K, Akiba, T. 登録日 2005-10-20 公開日 2006-07-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Structural phase transition of monoclinic crystals of hen egg-white lysozyme ACTA CRYSTALLOGR.,SECT.D, 62, 2006
3HRB	p38 kinase Crystal structure in complex with small molecule inhibitor 分子名称: Mitogen-activated protein kinase 14, [3-amino-2-(2-methylphenyl)-1-oxidopyridin-4-yl](2,4-difluorophenyl)methanone 著者 Segarra, V, Lumeras, W, Vidal, B, Leonard, P, Fisher, M, Lamers, M. 登録日 2009-06-09 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Design, synthesis, and structure-activity relationships of aminopyridine N-oxides, a novel scaffold for the potent and selective inhibition of p38 mitogen activated protein kinase J.Med.Chem., 52, 2009
2D4K	Monoclinic hen egg-white lysozyme crystallized at 313K 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION 著者 Harata, K, Akiba, T. 登録日 2005-10-20 公開日 2006-07-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Structural phase transition of monoclinic crystals of hen egg-white lysozyme ACTA CRYSTALLOGR.,SECT.D, 62, 2006
5TCO	Human p38 MAP Kinase in Complex with Dibenzosuberone Compound 1 分子名称: 3-[(3-benzamido-4-fluoranyl-phenyl)amino]-~{N}-(2-morpholin-4-ylethyl)-11-oxidanylidene-5,6-dihydrodibenzo[1,2-~{d}:1',2'-~{f}][7]annulene-9-carboxamide, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Mayer-Wrangowski, S.C, Rauh, D. 登録日 2016-09-15 公開日 2017-04-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Optimized Target Residence Time: Type I1/2 Inhibitors for p38 alpha MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R-Spine. Angew. Chem. Int. Ed. Engl., 56, 2017
5VXN	Structure of two RcsB dimers bound to two parallel DNAs. 分子名称: DNA (5'-D(*GP*AP*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*TP*CP*TP*TP*AP*GP*AP*TP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*TP*CP*TP*TP*AP*GP*A)-3'), Transcriptional regulatory protein RcsB 著者 Filippova, E.V, Minasov, G, Pshenychnyi, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-05-23 公開日 2018-03-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.375 Å) 主引用文献 Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB. MBio, 9, 2018
4F95	Crystal structure of human inosine triphosphate pyrophosphatase P32T variant 分子名称: Inosine triphosphate pyrophosphatase 著者 Simone, P.D, Pavlov, Y.I, Borgstahl, G.E.O. 登録日 2012-05-18 公開日 2013-04-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core. J.Struct.Biol., 182, 2013
2CVF	Crystal structure of the RadB recombinase 分子名称: DNA repair and recombination protein radB 著者 Akiba, T, Ishii, N, Rashid, N, Morikawa, M, Imanaka, T, Harata, K. 登録日 2005-06-03 公開日 2005-08-09 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of RadB recombinase from a hyperthermophilic archaeon, Thermococcus kodakaraensis KOD1: an implication for the formation of a near-7-fold helical assembly Nucleic Acids Res., 33, 2005
2D4I	Monoclinic hen egg-white lysozyme crystallized at pH4.5 form heavy water solution 分子名称: Lysozyme C, NITRATE ION, SODIUM ION 著者 Harata, K, Akiba, T. 登録日 2005-10-20 公開日 2006-07-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Structural phase transition of monoclinic crystals of hen egg-white lysozyme ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2FQ1	Crystal structure of the two-domain non-ribosomal peptide synthetase EntB containing isochorismate lyase and aryl-carrier protein domains 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Isochorismatase, ... 著者 Drake, E.J, Nicolai, D.A, Gulick, A.M. 登録日 2006-01-17 公開日 2006-05-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain. Chem.Biol., 13, 2006
2IDV	Crystal structure of wheat C113S mutant EIF4E bound TO 7-methyl-GDP 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic translation initiation factor 4E-1 著者 Monzingo, A.F, Dutt-Chaudhuri, A, Sadow, J, Dhaliwal, S, Hoffman, D.W, Robertus, J.D, Browning, K.S. 登録日 2006-09-15 公開日 2007-06-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structure of eukaryotic translation initiation factor-4E from wheat reveals a novel disulfide bond. Plant Physiol., 143, 2007
2I0H	The structure of p38alpha in complex with an arylpyridazinone 分子名称: 2-(3-{(2-CHLORO-4-FLUOROPHENYL)[1-(2-CHLOROPHENYL)-6-OXO-1,6-DIHYDROPYRIDAZIN-3-YL]AMINO}PROPYL)-1H-ISOINDOLE-1,3(2H)-DIONE, GLYCEROL, Mitogen-activated protein kinase 14 著者 Natarajan, S.R, Heller, S.T, Nam, K, Singh, S.B, Scapin, G, Patel, S, Thompson, J.E, Fitzgerald, C.E, O'Keefe, S.J. 登録日 2006-08-10 公開日 2006-10-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 p38 MAP Kinase Inhibitors Part 6: 2-Arylpyridazin-3-ones as templates for inhibitor design. Bioorg.Med.Chem.Lett., 16, 2006
2GAS	Crystal Structure of Isoflavone Reductase 分子名称: isoflavone reductase 著者 Wang, X, He, X, Lin, J, Shao, H, Chang, Z, Dixon, R.A. 登録日 2006-03-09 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of Isoflavone Reductase from Alfalfa (Medicago sativa L.) J.Mol.Biol., 358, 2006
3E90	West Nile vi rus NS2B-NS3protease in complexed with inhibitor Naph-KKR-H 分子名称: NS2B cofactor, NS3 protease, N~2~-(naphthalen-2-ylcarbonyl)-L-lysyl-N-[(1S)-4-carbamimidamido-1-formylbutyl]-L-lysinamide 著者 Martin, J.L, Robin, G. 登録日 2008-08-21 公開日 2009-01-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation J.Mol.Biol., 385, 2009
4GD5	X-ray Crystal Structure of a Putative Phosphate ABC Transporter Substrate-Binding Protein with Bound Phosphate from Clostridium perfringens 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Brunzelle, J.S, Wawrzak, Z, Onopriyenko, O, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-07-31 公開日 2012-08-15 最終更新日 2013-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 X-ray Crystal Structure of a Putative Phosphate ABC Transporter Substrate-Binding Protein with Bound Phosphate from Clostridium perfringens To be Published
2HOG	crystal structure of Chek1 in complex with inhibitor 20 分子名称: (5-{3-[5-(PIPERIDIN-1-YLMETHYL)-1H-INDOL-2-YL]-1H-INDAZOL-6-YL}-2H-1,2,3-TRIAZOL-4-YL)METHANOL, Serine/threonine-protein kinase Chk1 著者 Yan, Y, Ikuta, M. 登録日 2006-07-14 公開日 2007-04-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6. Bioorg.Med.Chem.Lett., 16, 2006
4JG9	X-ray Crystal Structure of a Putative Lipoprotein from Bacillus anthracis 分子名称: Lipoprotein 著者 Brunzelle, J.S, Wawrzak, Z, Onopriyenko, O, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-02-28 公開日 2013-03-20 実験手法 X-RAY DIFFRACTION (2.425 Å) 主引用文献 X-ray Crystal Structure of a Putative Lipoprotein from Bacillus anthracis To be Published
2LGC	Joint NMR and X-ray refinement reveals the structure of a novel dibenzo[a,d]cycloheptenone inhibitor/p38 MAP kinase complex in solution 分子名称: Mitogen-activated protein kinase 14 著者 Habeck, M. 登録日 2011-07-25 公開日 2012-07-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Inferential NMR/X-ray-based structure determination of a dibenzo[a,d]cycloheptenone inhibitor-p38alpha MAP kinase complex in solution Angew.Chem.Int.Ed.Engl., 51, 2012
4KIQ	Crystal structure of mitogen-activated protein kinase 14 (P38-H5) complex with ETHYL 6-((5-(CYCLOPROPYLCARBAMOYL)-2-METHYLPHENYL)CARBAMOYL)-1H-INDOLE-1-CARBOXYLATE 分子名称: Mitogen-activated protein kinase 14, ethyl 6-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]carbamoyl}-1H-indole-1-carboxylate 著者 Sack, J.S, Tokarski, J.S. 登録日 2013-05-02 公開日 2013-06-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Identification of Novel P38-Alpha Isoform Selective Kinase Inhibitors Having an Unprecedented P38-Alpha Binding Mode Bioorg.Med.Chem.Lett., 23, 2013
4KIP	Crystal structure of mitogen-activated protein kinase 14 (P38-H5) complex with 2-(2-CHLOROPHENYL)-N-(5-(CYCLOPROPYLCARBAMOYL)-2-METHYLPHENYL)-1,3-THIAZOLE-5-CARBOXAMIDE 分子名称: 2-(2-chlorophenyl)-N-[5-(cyclopropylcarbamoyl)-2-methylphenyl]-1,3-thiazole-5-carboxamide, Mitogen-activated protein kinase 14 著者 Sack, J.S, Tokarski, J.S. 登録日 2013-05-02 公開日 2013-06-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 The Identification of Novel P38-Alpha Isoform Selective Kinase Inhibitors Having an Unprecedented P38-Alpha Binding Mode Bioorg.Med.Chem.Lett., 23, 2013
4L7V	Crystal structure of Protein L-isoaspartyl-O-methyltransferase of Vibrio cholerae 分子名称: ACETATE ION, CALCIUM ION, Protein-L-isoaspartate O-methyltransferase, ... 著者 Chatterjee, T, Mukherjee, D, Chakrabarti, P. 登録日 2013-06-14 公開日 2014-06-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure and activity of protein L-isoaspartyl-O-methyltransferase from Vibrio cholerae, and the effect of AdoHcy binding. Arch.Biochem.Biophys., 583, 2015

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