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4ZLK
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BU of 4zlk by Molmil
Crystal structure of mouse myosin-5a in complex with calcium-bound calmodulin
分子名称: CALCIUM ION, Calmodulin, Unconventional myosin-Va
著者Shen, M, Zhang, N, Zheng, S, Zhang, W.-B, Zhang, H.-M, Lu, Z, Su, Q.P, Sun, Y, Ye, K, Li, X.-D.
登録日2015-05-01
公開日2016-05-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Structural basis for calcium regulation of myosin 5 motor function
To Be Published
7MIS
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BU of 7mis by Molmil
Cryo-EM structure of SidJ-SdeC-CaM reaction intermediate complex
分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
著者Osinski, A, Black, M.H, Pawlowski, K, Chen, Z, Li, Y, Tagliabracci, V.S.
登録日2021-04-17
公開日2021-08-18
最終更新日2021-11-17
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural and mechanistic basis for protein glutamylation by the kinase fold.
Mol.Cell, 81, 2021
1S6J
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BU of 1s6j by Molmil
N-terminal Region of the Ca2+-saturated calcium regulatory domain (CLD) from Soybean Calcium-dependent Protein Kinase-alpha (CDPK)
分子名称: CALCIUM ION, Calcium-dependent protein kinase SK5
著者Weljie, A.M, Vogel, H.J.
登録日2004-01-23
公開日2004-12-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure and Backbone Dynamics of the N-Terminal Region of the Calcium Regulatory Domain from Soybean Calcium-Dependent Protein Kinase alpha
Biochemistry, 42, 2004
2LMU
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BU of 2lmu by Molmil
Androcam at high calcium
分子名称: CALCIUM ION, Calmodulin-related protein 97A
著者Joshi, M.K, Moran, S.T, Beckingham, K.M, Mackenzie, K.R.
登録日2011-12-12
公開日2012-08-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of androcam supports specialized interactions with myosin VI.
Proc.Natl.Acad.Sci.USA, 109, 2012
5X2E
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BU of 5x2e by Molmil
Crystal structure of Calmodulin like domain of CsTAL3 (1-81aa)
分子名称: CALCIUM ION, Tegumental protein 20.8 kDa
著者Jo, C.H, Hwang, K.Y.
登録日2017-01-31
公開日2017-08-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.299 Å)
主引用文献Structural insights into a 20.8-kDa tegumental-allergen-like (TAL) protein from Clonorchis sinensis
Sci Rep, 7, 2017
2LMV
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BU of 2lmv by Molmil
Androcam at high calcium with three explicit Ca2+
分子名称: CALCIUM ION, Calmodulin-related protein 97A
著者Joshi, M.K, Moran, S.T, Beckingham, K.M, Mackenzie, K.R.
登録日2011-12-12
公開日2012-08-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of androcam supports specialized interactions with myosin VI.
Proc.Natl.Acad.Sci.USA, 109, 2012
2LMT
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BU of 2lmt by Molmil
NMR structure of Androcam
分子名称: CALCIUM ION, Calmodulin-related protein 97A
著者Joshi, M.K, Moran, S.T, Beckingham, K.M, Mackenzie, K.R.
登録日2011-12-12
公開日2012-08-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of androcam supports specialized interactions with myosin VI.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YGG
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BU of 2ygg by Molmil
Complex of CaMBR and CaM
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ...
著者Koester, S, Yildiz, O.
登録日2011-04-15
公開日2011-09-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.227 Å)
主引用文献Structure of Human Na+/H+ Exchanger Nhe1 Regulatory Region in Complex with Cam and Ca2+
J.Biol.Chem., 286, 2011
2W4J
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BU of 2w4j by Molmil
X-ray structure of a DAP-Kinase 2-277
分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, DEATH-ASSOCIATED PROTEIN KINASE 1, ...
著者De Diego, I, Kuper, J, Lehmann, F, Wilmanns, M.
登録日2008-11-27
公開日2009-12-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献X-Ray Structure of a Dap-Kinase Calmodulin Complex
To be Published
1S6I
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BU of 1s6i by Molmil
Ca2+-regulatory region (CLD) from soybean calcium-dependent protein kinase-alpha (CDPK) in the presence of Ca2+ and the junction domain (JD)
分子名称: CALCIUM ION, Calcium-dependent protein kinase SK5
著者Weljie, A.M, Vogel, H.J.
登録日2004-01-23
公開日2004-06-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Unexpected structure of the Ca2+-regulatory region from soybean calcium-dependent protein kinase-alpha
J.Biol.Chem., 279, 2004
4DJC
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BU of 4djc by Molmil
1.35 A crystal structure of the NaV1.5 DIII-IV-Ca/CaM complex
分子名称: CALCIUM ION, Calmodulin, ISOPROPYL ALCOHOL, ...
著者Sarhan, M.F, Tung, C.-C, Van Petegem, F, Ahern, C.A.
登録日2012-02-01
公開日2012-02-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Crystallographic basis for calcium regulation of sodium channels.
Proc.Natl.Acad.Sci.USA, 109, 2012
3OXQ
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BU of 3oxq by Molmil
Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Kim, E.Y, Rumpf, C.H, Van Petegem, F, Arant, R, Findeisen, F, Cooley, E.S, Isacoff, E.Y, Minor, D.L.
登録日2010-09-21
公開日2010-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization.
Embo J., 29, 2010
5V02
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BU of 5v02 by Molmil
A positive allosteric modulator binding pocket in SK2 ion channels is shared by Riluzole and CyPPA
分子名称: 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine, CALCIUM ION, Calmodulin-1, ...
著者Liu, S.
登録日2017-02-28
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献An Intracellular Allosteric Modulator Binding Pocket in SK2 Ion Channels Is Shared by Multiple Chemotypes.
Structure, 26, 2018
5H7D
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BU of 5h7d by Molmil
Crystal structure of the YgjG-protein A-Zpa963-calmodulin complex
分子名称: CALCIUM ION, Putrescine aminotransferase,Immunoglobulin G-binding protein A, Zpa963,Calmodulin
著者Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O.
登録日2016-11-17
公開日2017-06-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
5YVB
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BU of 5yvb by Molmil
Structure of CaMKK2 in complex with CKI-011
分子名称: (3Z)-5-chloro-3-[(1-methyl-1H-pyrazol-4-yl)methylidene]-1,3-dihydro-2H-indol-2-one, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ...
著者Niwa, H, Handa, N, Yokoyama, S.
登録日2017-11-24
公開日2018-12-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99, 2020
5YV9
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BU of 5yv9 by Molmil
Structure of CaMKK2 in complex with CKI-009
分子名称: 5-chloro-2-methoxy-4[(1Z)-3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl]aminobenzoic acid, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ...
著者Niwa, H, Handa, N, Yokoyama, S.
登録日2017-11-24
公開日2018-12-05
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99, 2020
5YVA
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BU of 5yva by Molmil
Structure of CaMKK2 in complex with CKI-010
分子名称: 3-(1H-tetrazol-5-yl)-10lambda~6~-thioxanthene-9,10,10-trione, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ...
著者Niwa, H, Handa, N, Yokoyama, S.
登録日2017-11-24
公開日2018-12-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.574 Å)
主引用文献Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99, 2020
5YV8
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BU of 5yv8 by Molmil
Structure of CaMKK2 in complex with CKI-002
分子名称: 1-amino-4-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ...
著者Niwa, H, Handa, N, Yokoyama, S.
登録日2017-11-24
公開日2018-12-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.927 Å)
主引用文献Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99, 2020
3HR4
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BU of 3hr4 by Molmil
Human iNOS Reductase and Calmodulin Complex
分子名称: CALCIUM ION, Calmodulin, FLAVIN MONONUCLEOTIDE, ...
著者Xia, C, Misra, I, Iyanaki, T, Kim, J.J.K.
登録日2009-06-08
公開日2009-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Regulation of Interdomain Interactions by CaM in Inducible Nitric Oxide Synthase
J.Biol.Chem., 2009
8UXL
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BU of 8uxl by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium and calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
8UXM
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BU of 8uxm by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
6Y4K
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BU of 6y4k by Molmil
Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and Fusicoccin A
分子名称: 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2, FUSICOCCIN
著者Lentini Santo, D, Obsilova, V, Obsil, T.
登録日2020-02-21
公開日2021-01-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins.
Acs Chem.Biol., 15, 2020
6Y6B
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BU of 6y6b by Molmil
Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and 16-OMe-Fusicoccin H
分子名称: (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[[(1~{S},3~{R},6~{S},7~{S},8~{R},9~{R},10~{R},11~{R},14~{S})-14-(me thoxymethyl)-3,10-dimethyl-9-oxidanyl-6-propan-2-yl-8-tricyclo[9.3.0.0^{3,7}]tetradecanyl]oxy]oxane-3,4,5-triol, 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2
著者Lentini Santo, D, Obsilova, V, Obsil, T.
登録日2020-02-26
公開日2021-02-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins.
Acs Chem.Biol., 15, 2020
7URY
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BU of 7ury by Molmil
Tetradecameric hub domain of CaMKII beta
分子名称: Calcium/calmodulin-dependent protein kinase type II subunit beta, D-MALATE
著者Ozden, C, Saha, S, Samkutty, A, Stratton, M.M, Garman, S.C, Perry, S.L.
登録日2022-04-22
公開日2022-05-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Polymer-based microfluidic device for on-chip counter-diffusive crystallization and in situ X-ray crystallography at room temperature.
Lab Chip, 23, 2023
6CZQ
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BU of 6czq by Molmil
A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model
分子名称: CALCIUM ION, Calmodulin-1, SULFATE ION, ...
著者Nam, Y.W, Zhang, M.
登録日2018-04-09
公開日2018-08-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A V-to-F substitution in SK2 channels causes Ca2+hypersensitivity and improves locomotion in a C. elegans ALS model.
Sci Rep, 8, 2018

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件を2024-11-06に公開中

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