5YVB
Structure of CaMKK2 in complex with CKI-011
Summary for 5YVB
Entry DOI | 10.2210/pdb5yvb/pdb |
Descriptor | Calcium/calmodulin-dependent protein kinase kinase 2, (3Z)-5-chloro-3-[(1-methyl-1H-pyrazol-4-yl)methylidene]-1,3-dihydro-2H-indol-2-one, GLYCEROL, ... (6 entities in total) |
Functional Keywords | atp-binding, kinase, serine/threonine-protein kinase, transferase, protein-inhibitor complex |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 34525.33 |
Authors | Niwa, H.,Handa, N.,Yokoyama, S. (deposition date: 2017-11-24, release date: 2018-12-05, Last modification date: 2023-11-22) |
Primary citation | Takaya, D.,Niwa, H.,Mikuni, J.,Nakamura, K.,Handa, N.,Tanaka, A.,Yokoyama, S.,Honma, T. Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method. J.Mol.Graph.Model., 99:107599-107599, 2020 Cited by PubMed: 32348940DOI: 10.1016/j.jmgm.2020.107599 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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