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5YVB

Structure of CaMKK2 in complex with CKI-011

Summary for 5YVB
Entry DOI10.2210/pdb5yvb/pdb
DescriptorCalcium/calmodulin-dependent protein kinase kinase 2, (3Z)-5-chloro-3-[(1-methyl-1H-pyrazol-4-yl)methylidene]-1,3-dihydro-2H-indol-2-one, GLYCEROL, ... (6 entities in total)
Functional Keywordsatp-binding, kinase, serine/threonine-protein kinase, transferase, protein-inhibitor complex
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight34525.33
Authors
Niwa, H.,Handa, N.,Yokoyama, S. (deposition date: 2017-11-24, release date: 2018-12-05, Last modification date: 2023-11-22)
Primary citationTakaya, D.,Niwa, H.,Mikuni, J.,Nakamura, K.,Handa, N.,Tanaka, A.,Yokoyama, S.,Honma, T.
Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99:107599-107599, 2020
Cited by
PubMed: 32348940
DOI: 10.1016/j.jmgm.2020.107599
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.02 Å)
Structure validation

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