5YVB
Structure of CaMKK2 in complex with CKI-011
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcium/calmodulin-dependent protein kinase kinase 2 | polymer | 298 | 33711.6 | 1 | UniProt (Q96RR4) Pfam (PF00069) | Homo sapiens (Human) | CaMKK 2,Calcium/calmodulin-dependent protein kinase kinase beta,CaMKK beta |
| 2 | B (A) | (3Z)-5-chloro-3-[(1-methyl-1H-pyrazol-4-yl)methylidene]-1,3-dihydro-2H-indol-2-one | non-polymer | 259.7 | 1 | Chemie (92C) | |||
| 3 | C, D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | G (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 5 | H (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | I (A) | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A: 158 - 448 (UniProt: Q96RR4)
| PDB | External Database | Details |
|---|---|---|
| Gly 151 | - | expression tag |
| Ser 152 | - | expression tag |
| Ser 153 | - | expression tag |
| Gly 154 | - | expression tag |
| Ser 155 | - | expression tag |
| Ser 156 | - | expression tag |
| Gly 157 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33711.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 813.7 | |
| All* | Total formula weight | 34525.3 |
