PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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5BK1	Crystal structure of maltose binding protein in complex with an endosteric synthetic antibody 分子名称: CHLORIDE ION, GLYCEROL, Maltose binding protein, ... 著者 Mukherjee, S, Kossiakoff, A.A. 登録日 2017-09-12 公開日 2018-01-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins. J. Biol. Chem., 293, 2018
5BJZ	Crystal structure of maltose binding protein in complex with an allosteric synthetic antibody 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... 著者 Mukherjee, S, Kossiakoff, A.A. 登録日 2017-09-12 公開日 2018-01-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins. J. Biol. Chem., 293, 2018
4F2M	Crystal structure of a TGEV coronavirus Spike fragment in complex with the TGEV neutralizing monoclonal antibody 1AF10 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... 著者 Reguera, J, Santiago, C, Mudgal, G, Ordono, D, Enjuanes, L, Casasnovas, J.M. 登録日 2012-05-08 公開日 2012-08-22 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies. Plos Pathog., 8, 2012
4JKP	Restricting HIV-1 Pathways for Escape using Rationally-Designed Anti-HIV-1 Antibodies 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody 45-46M2, Light chain of antibody 45-46M2, ... 著者 Diskin, R, Bjorkman, P.J. 登録日 2013-03-11 公開日 2013-05-15 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies. J.Exp.Med., 210, 2013
6BB4	Fab/epitope complex of mouse monoclonal antibody C5.2 targeting a phospho-tau epitope. 分子名称: Microtubule-associated protein tau, Mouse monoclonal antibody C5.2 Fab heavy chain, Mouse monoclonal antibody C5.2 Fab light chain, ... 著者 Chukwu, J.E, Kong, X.-P. 登録日 2017-10-16 公開日 2018-05-02 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Tau Antibody Structure Reveals a Molecular Switch Defining a Pathological Conformation of the Tau Protein. Sci Rep, 8, 2018
4UT6	Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 B7 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7, ... 著者 Rouvinski, A, Guardado-Calvo, P, Barba-Spaeth, G, Duquerroy, S, Vaney, M.C, Rey, F.A. 登録日 2014-07-18 公開日 2015-01-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses. Nature, 520, 2015
4PPT	Engineered Dual Specific VHH Antibody in Complex with a Nickel (II) Ion 分子名称: Engineered single domain VHH antibody, NICKEL (II) ION, SULFATE ION 著者 Fanning, S.W, Walter, R, Horn, J.R. 登録日 2014-02-27 公開日 2014-09-03 最終更新日 2014-10-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site. Protein Eng.Des.Sel., 27, 2014
8ELI	Broadly neutralizing antibody VRC34-combo.1 in complex with HIV fusion peptide (residue 512-519) 分子名称: Fusion peptide, VRC34-combo.1 Fab Heavy chain, VRC34-combo.1 Fab Light chain 著者 Xu, K, Kwong, P.D. 登録日 2022-09-24 公開日 2023-09-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site. Nat Commun, 14, 2023
6P79	Engineered single chain antibody C9+C14 ScFv 分子名称: Engineered antibody heavy chain, Engineered antibody light chain 著者 Zhang, Y, Li, W, Marshall, N. 登録日 2019-06-05 公開日 2020-04-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.583 Å) 主引用文献 Computer-based Engineering of Thermostabilized Antibody Fragments. Aiche J, 66, 2020
6KNM	Apelin receptor in complex with single domain antibody 分子名称: Apelin receptor,Rubredoxin,Apelin receptor, Single domain antibody JN241, ZINC ION 著者 Ma, Y.B, Ding, Y, Song, X, Ma, X, Li, X, Zhang, N, Song, Y, Sun, Y, Shen, Y, Zhong, W, Hu, L.A, Ma, Y.L, Zhang, M.Y. 登録日 2019-08-06 公開日 2020-01-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure-guided discovery of a single-domain antibody agonist against human apelin receptor. Sci Adv, 6, 2020
8G4M	Vaccine-elicited human antibody 2C06 in complex with HIV-1 envelope trimer BG505 DS-SOSIP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... 著者 Wang, S, Morano, N.C, Shapiro, L, Kwong, P.D. 登録日 2023-02-10 公開日 2023-07-12 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide. Cell Rep, 42, 2023
4HS8	Hepatitus C envelope glycoprotein E2 fragment 412-423 with humanized and affinity-matured antibody hu5B3.v3 分子名称: E2-peptide, GLYCEROL, SULFATE ION, ... 著者 Eigenbrot, C, Ultsch, M. 登録日 2012-10-29 公開日 2013-04-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Glycan shifting on hepatitis C virus (HCV) e2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies. J.Mol.Biol., 425, 2013
6P9J	crystal structure of human anti staphylococcus aureus antibody STAU-229 Fab 分子名称: TRIS(HYDROXYETHYL)AMINOMETHANE, human anti staphylococcus aureus antibody STAU-229 Fab heavy chain, human anti staphylococcus aureus antibody STAU-229 Fab light chain 著者 Dong, J, Crowe, J.E. 登録日 2019-06-10 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis. Mbio, 10, 2019
6P9I	crystal structure of human anti staphylococcus aureus antibody STAU-399 Fab 分子名称: human anti staphylococcus aureus antibody STAU-399 Fab heavy chain, human anti staphylococcus aureus antibody STAU-399 Fab light chain 著者 Dong, J, Crowe, J.E. 登録日 2019-06-10 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Human V H 1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis. Mbio, 10, 2019
7PI3	PfCyRPA bound to Fab fragments from monoclonal antibodies Cy.003, Cy.004 and Cy.007 分子名称: CALCIUM ION, Cysteine-rich protective antigen, Monoclonal antibody Cy.003 heavy chain, ... 著者 Ragotte, R.J, Higgins, M.K. 登録日 2021-08-19 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.269 Å) 主引用文献 Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
6VY4	Crystal structure of Hendra receptor binding protein head domain in complex with human neutralizing antibody HENV-32 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-Hendra receptor binding protein antibody HENV-32 Fab heavy chain, Anti-Hendra receptor binding protein antibody HENV-32 Fab light chain, ... 著者 Dong, J, Crowe, J.E. 登録日 2020-02-25 公開日 2020-12-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Potent Henipavirus Neutralization by Antibodies Recognizing Diverse Sites on Hendra and Nipah Virus Receptor Binding Protein. Cell, 183, 2020
7PHU	PfRH5 bound to monoclonal antibody R5.015 and R5.016 Fab fragments 分子名称: Monoclonal antibody R5.015 heavy chain, Monoclonal antibody R5.015 light chain, Monoclonal antibody R5.016 heavy chain, ... 著者 Ragotte, R.J, Higgins, M.K. 登録日 2021-08-18 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
4TYU	Homodimeric Single Domain Antibody (sdAb) against Staphylococcal enterotoxin B (SEB) 分子名称: SULFATE ION, Single Domain Antibody 著者 Legler, P.M. 登録日 2014-07-09 公開日 2014-09-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structural and mutational analysis of a monomeric and dimeric form of a single domain antibody with implications for protein misfolding. Proteins, 82, 2014
4U05	Homodimeric Single Domain Antibody (sdAb) against Staphylococcal enterotoxin B (SEB) S74A Variant 分子名称: SULFATE ION, Single Domain Antibody 著者 Legler, P.M. 登録日 2014-07-11 公開日 2014-09-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and mutational analysis of a monomeric and dimeric form of a single domain antibody with implications for protein misfolding. Proteins, 82, 2014
7PHW	PfCyRPA bound to monoclonal antibody Cy.004 Fab fragment 分子名称: CALCIUM ION, Cysteine-rich protective antigen, Monoclonal antibody Cy.004 heavy chain, ... 著者 Ragotte, R.J, Higgins, M.K. 登録日 2021-08-18 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.793 Å) 主引用文献 Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
7PI7	PfCyRPA bound to monoclonal antibody Cy.002 Fab fragment 分子名称: Cysteine-rich protective antigen, Monoclonal antibody Cy.002 heavy chain, Monoclonal antibody Cy.002 light chain 著者 Ragotte, R.J, Higgins, M.K. 登録日 2021-08-19 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
7PHV	PfCyRPA bound to monoclonal antibody Cy.007 Fab fragment 分子名称: AMMONIUM ION, Cysteine-rich protective antigen, Monoclonal antibody Cy.007 heavy chain, ... 著者 Ragotte, R.J, Higgins, M.K. 登録日 2021-08-18 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.091 Å) 主引用文献 Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
7PI2	PfCyRPA bound to monoclonal antibody Cy.003 Fab fragment 分子名称: Cysteine-rich protective antigen, Monoclonal antibody Cy.003 heavy chain, Monoclonal antibody Cy.003 light chain 著者 Ragotte, R.J, Higgins, M.K. 登録日 2021-08-19 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
7RDA	Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.138 分子名称: Circumsporozoite protein, antibody m43.138 heavy chain, antibody m43.138 light chain 著者 Xu, K, Kwong, P.D. 登録日 2021-07-09 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021
7RD9	Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.159 分子名称: Circumsporozoite protein, antibody m43.159 heavy chain, antibody m43.159 light chain 著者 Xu, K, Kwong, P.D. 登録日 2021-07-09 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

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