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7Q3L
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BU of 7q3l by Molmil
Human 17S U2 snRNP 5' domain
分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ...
著者Tholen, J, Galej, W.P.
登録日2021-10-28
公開日2022-03-30
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structural basis of branch site recognition by the human spliceosome.
Science, 375, 2022
7DVQ
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BU of 7dvq by Molmil
Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ...
著者Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y.
登録日2021-01-14
公開日2021-03-31
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structure of the activated human minor spliceosome.
Science, 371, 2021
7B9V
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BU of 7b9v by Molmil
Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound
分子名称: 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ...
著者Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K.
登録日2020-12-14
公開日2021-03-10
最終更新日2021-04-14
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for conformational equilibrium of the catalytic spliceosome.
Mol.Cell, 81, 2021
5NRL
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BU of 5nrl by Molmil
Structure of a pre-catalytic spliceosome.
分子名称: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ...
著者Plaschka, C, Lin, P.-C, Nagai, K.
登録日2017-04-24
公開日2017-05-31
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Structure of a pre-catalytic spliceosome.
Nature, 546, 2017
7DCO
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BU of 7dco by Molmil
Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5 angstrom
分子名称: BJ4_G0014900.mRNA.1.CDS.1, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0037700.mRNA.1.CDS.1, ...
著者Bai, R, Wan, R, Yan, C, Qi, J, Zhang, P, Lei, J, Shi, Y.
登録日2020-10-26
公開日2021-03-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.
Science, 371, 2021
6FT6
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BU of 6ft6 by Molmil
Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors
分子名称: 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ...
著者Schuller, J.M, Falk, S, Conti, E.
登録日2018-02-20
公開日2018-03-28
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure of the nuclear exosome captured on a maturing preribosome.
Science, 360, 2018
6ICZ
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BU of 6icz by Molmil
Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Zhang, X, Zhan, X, Yan, C, Shi, Y.
登録日2018-09-07
公開日2019-03-13
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
5O9Z
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BU of 5o9z by Molmil
Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ...
著者Bertram, K, Kastner, B.
登録日2017-06-20
公開日2017-08-16
最終更新日2018-10-24
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell, 170, 2017
6ID1
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BU of 6id1 by Molmil
Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ...
著者Zhang, X, Zhan, X, Yan, C, Shi, Y.
登録日2018-09-07
公開日2019-03-13
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
7D4I
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BU of 7d4i by Molmil
Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
著者Du, Y, Zhang, J, An, W, Ye, K.
登録日2020-09-24
公開日2021-10-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1
To Be Published
7D63
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BU of 7d63 by Molmil
Cryo-EM structure of 90S preribosome with inactive Utp24 (state C)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
著者Du, Y, Zhang, J, An, W, Ye, K.
登録日2020-09-29
公開日2021-10-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (12.3 Å)
主引用文献Cryo-EM structure of 90S preribosome with inactive Utp24 (state C)
To Be Published
7D5T
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BU of 7d5t by Molmil
Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
著者Du, Y, Zhang, J, An, W, Ye, K.
登録日2020-09-28
公開日2021-10-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1)
To Be Published
8B9I
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BU of 8b9i by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ...
著者Jagtap, P.K.A, Hennig, J.
登録日2022-10-06
公開日2023-10-18
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
8B9G
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BU of 8b9g by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4 and U10 RNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ...
著者Jagtap, P.K.A, Hennig, J.
登録日2022-10-06
公開日2023-10-18
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
8B9J
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BU of 8b9j by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ...
著者Jagtap, P.K.A, Hennig, J.
登録日2022-10-06
公開日2023-10-18
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
8B9L
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BU of 8b9l by Molmil
Cryo-EM structure of MLE
分子名称: Dosage compensation regulator
著者Jagtap, P.K.A, Hennig, J.
登録日2022-10-06
公開日2023-10-18
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
8B9K
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BU of 8b9k by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4 and SL7modUUC RNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, SL7modUUC, ...
著者Jagtap, P.K.A, Hennig, J.
登録日2022-10-06
公開日2023-10-18
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.04 Å)
主引用文献Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
8CH6
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BU of 8ch6 by Molmil
Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
著者Cretu, C, Schmitzova, J, Pena, V.
登録日2023-02-07
公開日2023-05-10
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural basis of catalytic activation in human splicing.
Nature, 617, 2023
8C6J
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BU of 8c6j by Molmil
Human spliceosomal PM5 C* complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Dybkov, O, Kastner, B, Luehrmann, R.
登録日2023-01-12
公開日2023-07-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins.
Sci Adv, 9, 2023
6EM3
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BU of 6em3 by Molmil
State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ...
著者Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R.
登録日2017-10-01
公開日2017-12-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
6QW6
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BU of 6qw6 by Molmil
Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Charenton, C, Wilkinson, M.E, Nagai, K.
登録日2019-03-05
公開日2019-04-17
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
6EM4
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BU of 6em4 by Molmil
State B architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ...
著者Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R.
登録日2017-10-01
公開日2017-12-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
6EM5
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BU of 6em5 by Molmil
State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes
分子名称: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
著者Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R.
登録日2017-10-01
公開日2017-12-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
6FF7
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BU of 6ff7 by Molmil
human Bact spliceosome core structure
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ...
著者Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H.
登録日2018-01-03
公開日2019-03-13
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
6QX9
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BU of 6qx9 by Molmil
Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Charenton, C, Wilkinson, M.E, Nagai, K.
登録日2019-03-07
公開日2019-04-17
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019

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