7Q3L
| Human 17S U2 snRNP 5' domain | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | 著者 | Tholen, J, Galej, W.P. | 登録日 | 2021-10-28 | 公開日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
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7DVQ
| Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... | 著者 | Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. | 登録日 | 2021-01-14 | 公開日 | 2021-03-31 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Structure of the activated human minor spliceosome. Science, 371, 2021
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7B9V
| Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound | 分子名称: | 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ... | 著者 | Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K. | 登録日 | 2020-12-14 | 公開日 | 2021-03-10 | 最終更新日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for conformational equilibrium of the catalytic spliceosome. Mol.Cell, 81, 2021
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5NRL
| Structure of a pre-catalytic spliceosome. | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | 著者 | Plaschka, C, Lin, P.-C, Nagai, K. | 登録日 | 2017-04-24 | 公開日 | 2017-05-31 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Structure of a pre-catalytic spliceosome. Nature, 546, 2017
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7DCO
| Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5 angstrom | 分子名称: | BJ4_G0014900.mRNA.1.CDS.1, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0037700.mRNA.1.CDS.1, ... | 著者 | Bai, R, Wan, R, Yan, C, Qi, J, Zhang, P, Lei, J, Shi, Y. | 登録日 | 2020-10-26 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2. Science, 371, 2021
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6FT6
| Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors | 分子名称: | 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ... | 著者 | Schuller, J.M, Falk, S, Conti, E. | 登録日 | 2018-02-20 | 公開日 | 2018-03-28 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
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6ICZ
| Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | 登録日 | 2018-09-07 | 公開日 | 2019-03-13 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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5O9Z
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6ID1
| Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | 登録日 | 2018-09-07 | 公開日 | 2019-03-13 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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7D4I
| Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F) | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Du, Y, Zhang, J, An, W, Ye, K. | 登録日 | 2020-09-24 | 公開日 | 2021-10-06 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1 To Be Published
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7D63
| Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Du, Y, Zhang, J, An, W, Ye, K. | 登録日 | 2020-09-29 | 公開日 | 2021-10-06 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (12.3 Å) | 主引用文献 | Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) To Be Published
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7D5T
| Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Du, Y, Zhang, J, An, W, Ye, K. | 登録日 | 2020-09-28 | 公開日 | 2021-10-06 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) To Be Published
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8B9I
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8B9G
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8B9J
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8B9L
| Cryo-EM structure of MLE | 分子名称: | Dosage compensation regulator | 著者 | Jagtap, P.K.A, Hennig, J. | 登録日 | 2022-10-06 | 公開日 | 2023-10-18 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
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8B9K
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8CH6
| Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex). | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Cretu, C, Schmitzova, J, Pena, V. | 登録日 | 2023-02-07 | 公開日 | 2023-05-10 | 最終更新日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Structural basis of catalytic activation in human splicing. Nature, 617, 2023
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8C6J
| Human spliceosomal PM5 C* complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | 著者 | Dybkov, O, Kastner, B, Luehrmann, R. | 登録日 | 2023-01-12 | 公開日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins. Sci Adv, 9, 2023
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6EM3
| State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
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6QW6
| Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Charenton, C, Wilkinson, M.E, Nagai, K. | 登録日 | 2019-03-05 | 公開日 | 2019-04-17 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
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6EM4
| State B architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
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6EM5
| State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | 分子名称: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
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6FF7
| human Bact spliceosome core structure | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | 登録日 | 2018-01-03 | 公開日 | 2019-03-13 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
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6QX9
| Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Charenton, C, Wilkinson, M.E, Nagai, K. | 登録日 | 2019-03-07 | 公開日 | 2019-04-17 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
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