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6ZLL
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Crystal Structure of UDP-Glucuronic acid 4-epimerase from Bacillus cereus in complex with UDP-Galacturonic acid and NAD
分子名称: (2S,3R,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic acid, Epimerase domain-containing protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Iacovino, L.G, Savino, S, Mattevi, A.
登録日2020-06-30
公開日2020-07-29
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction.
J.Biol.Chem., 295, 2020
6ZLK
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Equilibrium Structure of UDP-Glucuronic acid 4-epimerase from Bacillus cereus in complex with UDP-Glucuronic acid/UDP-Galacturonic acid and NAD
分子名称: (2S,3R,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic acid, Epimerase domain-containing protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Iacovino, L.G, Mattevi, A.
登録日2020-06-30
公開日2020-07-29
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction.
J.Biol.Chem., 295, 2020
6O7H
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BU of 6o7h by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system
分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm2, Csm3, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
1DBN
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BU of 1dbn by Molmil
MAACKIA AMURENSIS LEUKOAGGLUTININ (LECTIN) WITH SIALYLLACTOSE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MANGANESE (II) ION, ...
著者Imberty, A, Gautier, C, Lescar, J, Loris, R.
登録日1999-11-03
公開日2000-06-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献An unusual carbohydrate binding site revealed by the structures of two Maackia amurensis lectins complexed with sialic acid-containing oligosaccharides.
J.Biol.Chem., 275, 2000
7TR4
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BU of 7tr4 by Molmil
MA2-MART1-HLAA0201
分子名称: Beta-2-microglobulin, GLYCEROL, HLA-A*02:01, ...
著者Yang, X, Jude, K.M, Garcia, K.C.
登録日2022-01-27
公開日2022-11-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy.
Nat.Biotechnol., 41, 2023
1DNP
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BU of 1dnp by Molmil
STRUCTURE OF DEOXYRIBODIPYRIMIDINE PHOTOLYASE
分子名称: 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, DNA PHOTOLYASE, FLAVIN-ADENINE DINUCLEOTIDE
著者Park, H.-W, Sancar, A, Deisenhofer, J.
登録日1995-07-03
公開日1996-08-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of DNA photolyase from Escherichia coli.
Science, 268, 1995
6P6W
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BU of 6p6w by Molmil
Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state
分子名称: Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb
著者Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-Din, T.M, Wang, L, Zheng, N, Catterall, W.A.
登録日2019-06-04
公開日2019-08-14
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.
Cell, 178, 2019
6USM
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Structure of nuclease domain of human parvovirus B19 non-structural protein 1 in complex with zinc
分子名称: Maltodextrin-binding protein, Non-structural protein NS1, ZINC ION, ...
著者Tewary, S.K.
登録日2019-10-28
公開日2020-12-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献B19 Parvovirus Non-structural protein 1 in complex with zinc
To Be Published
6PMJ
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BU of 6pmj by Molmil
Sigm28-transcription initiation complex with specific promoter at the state 2
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Liu, B, Shi, W.
登録日2019-07-02
公開日2020-05-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structural basis of bacterial sigma28-mediated transcription reveals roles of the RNA polymerase zinc-binding domain.
Embo J., 39, 2020
6XDS
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BU of 6xds by Molmil
Crystal structure of MBP-TREM2 Ig domain fusion with fragment, 2-((4-bromophenyl)amino)ethan-1-ol
分子名称: 2-[(4-bromophenyl)amino]ethan-1-ol, DIMETHYL SULFOXIDE, Sugar ABC transporter substrate-binding protein,Triggering receptor expressed on myeloid cells 2, ...
著者Su, H.P.
登録日2020-06-11
公開日2021-02-17
実験手法X-RAY DIFFRACTION (1.466 Å)
主引用文献Development of a robust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy.
Protein Expr.Purif., 179, 2021
6XRX
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BU of 6xrx by Molmil
Crystal structure of the mosquito protein AZ1 as an MBP fusion
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Maltose/maltodextrin-binding periplasmic protein, ...
著者Pedersen, L.C, Mueller, G.A, Foo, A.C.Y.
登録日2020-07-14
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The mosquito protein AEG12 displays both cytolytic and antiviral properties via a common lipid transfer mechanism.
Proc.Natl.Acad.Sci.USA, 118, 2021
1DMB
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BU of 1dmb by Molmil
REFINED 1.8 ANGSTROMS STRUCTURE REVEALS THE MECHANISM OF BINDING OF A CYCLIC SUGAR, BETA-CYCLODEXTRIN, TO THE MALTODEXTRIN BINDING PROTEIN
分子名称: Cycloheptakis-(1-4)-(alpha-D-glucopyranose), D-MALTODEXTRIN BINDING PROTEIN
著者Sharff, A.J, Quiocho, F.A.
登録日1993-06-10
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Refined 1.8-A structure reveals the mode of binding of beta-cyclodextrin to the maltodextrin binding protein.
Biochemistry, 32, 1993
6XDJ
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BU of 6xdj by Molmil
Crystal Structure Analysis of MBP-SIN3
分子名称: Maltodextrin-binding protein,Transcriptional regulatory protein SIN3, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose
著者Seo, H.-S, Dhe-Paganon, S.
登録日2020-06-10
公開日2021-06-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure Analysis of MBP-SIN3
To be published
6PGQ
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BU of 6pgq by Molmil
Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (22-32)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Calcitonin, ...
著者Lee, S, Pioszak, A.A.
登録日2019-06-24
公開日2020-02-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics.
J.Mol.Biol., 432, 2020
6ZWM
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BU of 6zwm by Molmil
cryo-EM structure of human mTOR complex 2, overall refinement
分子名称: ACETYL GROUP, INOSITOL HEXAKISPHOSPHATE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Scaiola, A, Mangia, F, Imseng, S, Boehringer, D, Ban, N, Maier, T.
登録日2020-07-28
公開日2020-11-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The 3.2- angstrom resolution structure of human mTORC2.
Sci Adv, 6, 2020
6XSW
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BU of 6xsw by Molmil
Structure of the Notch3 NRR in complex with an antibody Fab Fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-N3 Fab Heavy Chain, ...
著者Bard, J.
登録日2020-07-16
公開日2021-07-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells.
Cell Rep Med, 2, 2021
7UN9
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BU of 7un9 by Molmil
SfSTING with c-di-GMP double fiber
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CD-NTase-associated protein 12
著者Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J.
登録日2022-04-09
公開日2022-07-27
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of an active bacterial TIR-STING filament complex.
Nature, 608, 2022
6OFW
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BU of 6ofw by Molmil
Dihydropteroate synthase from Xanthomonas albilineans in complex with 7,8-dihydropteroate
分子名称: 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoic acid, Dihydropteroate synthase, SULFATE ION
著者Oliveira, A.A, Guido, R.V.C, Maluf, F.V, Bueno, R.V, Lima, G.M.A.
登録日2019-04-01
公開日2020-04-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Dihydropteroate synthase from Xanthomonas albilineans in complex with 7,8-dihydropteroate
To Be Published
6X91
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BU of 6x91 by Molmil
Crystal structure of MBP-fused human APOBEC1
分子名称: CACODYLATE ION, Maltodextrin-binding protein, C->U-editing enzyme APOBEC-1 chimera, ...
著者Wolfe, A.D, Li, S.-X, Chen, X.S.
登録日2020-06-02
公開日2020-12-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity.
NAR Cancer, 2, 2020
7A9C
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BU of 7a9c by Molmil
Human serum albumin (HSA) crystallized in the presence of yttrium (III) chloride
分子名称: Albumin, YTTRIUM (III) ION
著者Zocher, G, Stehle, T.
登録日2020-09-01
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Protein Crystallization in the Presence of a Metastable Liquid-Liquid Phase Separation
Cryst.Growth Des., 2020
4QSZ
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BU of 4qsz by Molmil
Crystal structure of mouse JMJd7 fused with maltose-binding protein
分子名称: CITRATE ANION, Maltose-binding periplasmic protein, JmjC domain-containing protein 7 chimera, ...
著者Liu, H, Wang, C, Zhang, G.Y.
登録日2014-07-06
公開日2015-07-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Crystal structure of mouse JMJd7 fused with maltose-binding protein
To be Published
6YBK
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BU of 6ybk by Molmil
Structure of MBP-Mcl-1 in complex with compound 4d
分子名称: (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-[2-(pyrazin-2-ylmethoxy)phenyl]propanoic acid, CHLORIDE ION, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, ...
著者Dokurno, P, Surgenor, A.E, Murray, J.B.
登録日2020-03-17
公開日2020-11-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor.
J.Med.Chem., 63, 2020
4RWF
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BU of 4rwf by Molmil
Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin
分子名称: 1,2-ETHANEDIOL, Adrenomedullin, Maltose transporter subunit, ...
著者Booe, J, Pioszak, A.
登録日2014-12-03
公開日2015-05-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor.
Mol.Cell, 58, 2015
6ZLA
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BU of 6zla by Molmil
Crystal Structure of UDP-Glucuronic acid 4-epimerase from Bacillus cereus in complex with NAD
分子名称: Epimerase domain-containing protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Iacovino, L.G, Mattevi, A.
登録日2020-06-30
公開日2020-07-29
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction.
J.Biol.Chem., 295, 2020
8R2O
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BU of 8r2o by Molmil
Huntingtin-Q17, 1-66, N-MBP fusion
分子名称: Maltodextrin-binding protein,Huntingtin, myristoylated N-terminal fragment, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Toledo-Sherman, L, Dominguez, C.
登録日2023-11-07
公開日2024-09-18
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Post-translational modifications in the first 17 amino acids of huntingtin influence self-association and interaction with membranes
To Be Published

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件を2024-10-16に公開中

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