7WU3
 
 | | Cryo-EM structure of the adhesion GPCR ADGRF1 in complex with miniGs | | 分子名称: | Adhesion G-protein coupled receptor F1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B. | | 登録日 | 2022-02-05 | | 公開日 | 2022-04-27 | | 最終更新日 | 2022-05-11 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1.
Nature, 604, 2022
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7WU2
 | | Cryo-EM structure of the adhesion GPCR ADGRD1 in complex with miniGs | | 分子名称: | Adhesion G-protein coupled receptor D1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Qu, X, Qiu, N, Wang, M, Zhao, Q, Wu, B. | | 登録日 | 2022-02-05 | | 公開日 | 2022-04-27 | | 最終更新日 | 2022-05-11 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1.
Nature, 604, 2022
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2IWK
 | | Inhibitor-bound form of nitrous oxide reductase from Achromobacter Cycloclastes at 1.7 Angstrom resolution | | 分子名称: | (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Paraskevopoulos, K, Antonyuk, S.V, Sawers, R.G, Eady, R.R, Hasnain, S.S. | | 登録日 | 2006-06-30 | | 公開日 | 2006-08-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Insight Into Catalysis of Nitrous Oxide Reductase from High-Resolution Structures of Resting and Inhibitor-Bound Enzyme from Achromobacter Cycloclastes.
J.Mol.Biol., 362, 2006
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1U9Y
 | | Crystal Structure of Phosphoribosyl Diphosphate Synthase from Methanocaldococcus jannaschii | | 分子名称: | Ribose-phosphate pyrophosphokinase | | 著者 | Kadziola, A, Johansson, E, Jepsen, C.H, McGuire, J, Larsen, S, Hove-Jensen, B. | | 登録日 | 2004-08-11 | | 公開日 | 2005-08-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Novel class III phosphoribosyl diphosphate synthase: structure and properties of the tetrameric, phosphate-activated, non-allosterically inhibited enzyme from Methanocaldococcus jannaschii
J.Mol.Biol., 354, 2005
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7V0B
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7V0D
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7KM9
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7KM7
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2BUC
 | | Crystal Structure Of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a Tetrahydroisoquinoline Inhibitor | | 分子名称: | (S)-2-[(R)-3-AMINO-4-(2-FLUORO-PHENYL)-BUTYRYL]-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID AMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Nordhoff, S, Cerezo-Galvez, S, Feurer, A, Hill, O, Matassa, V.G, Metz, G, Rummey, C, Thiemann, M, Edwards, P.J. | | 登録日 | 2005-06-09 | | 公開日 | 2006-01-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The reversed binding of beta-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors.
Bioorg. Med. Chem. Lett., 16, 2006
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1JJ3
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2IWF
 | | Resting form of pink nitrous oxide reductase from Achromobacter Cycloclastes | | 分子名称: | (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Paraskevopoulos, K, Antonyuk, S.V, Sawers, R.G, Eady, R.R, Hasnain, S.S. | | 登録日 | 2006-06-29 | | 公開日 | 2006-08-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Insight Into Catalysis of Nitrous Oxide Reductase from High-Resolution Structures of Resting and Inhibitor-Bound Enzyme from Achromobacter Cycloclastes.
J.Mol.Biol., 362, 2006
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1LQ2
 | | Crystal structure of barley beta-D-glucan glucohydrolase isoenzyme Exo1 in complex with gluco-phenylimidazole | | 分子名称: | (5R,6R,7S,8S)-5-(HYDROXYMETHYL)-2-PHENYL-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hrmova, M, De Gori, R, Smith, B.J, Vasella, A, Varghese, J.N, Fincher, G.B. | | 登録日 | 2002-05-09 | | 公開日 | 2003-11-18 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Three-dimensional Structure of the Barley {beta}-D-Glucan Glucohydrolase in Complex with a Transition State Mimic.
J.Biol.Chem., 279, 2004
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1KZI
 | | Crystal Structure of EcTS/dUMP/THF Complex | | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (6S)-5,6,7,8-TETRAHYDROFOLATE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ... | | 著者 | Fritz, T.A, Liu, L, Finer-Moore, J.S, Stroud, R.M. | | 登録日 | 2002-02-06 | | 公開日 | 2002-07-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Tryptophan 80 and leucine 143 are critical for the hydride transfer step of thymidylate synthase by controlling active site access.
Biochemistry, 41, 2002
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1NWL
 | | Crystal structure of the PTP1B complexed with SP7343-SP7964, a pTyr mimetic | | 分子名称: | 3-(4-{2-[2-(2-BROMO-ACETYLAMINO)-ETHYLDISULFANYL]-ETHYLCARBAMOYL}-CYCLOHEXYLCARBAMOYL)-PYRAZINE-2-CARBOXYLIC ACID, MAGNESIUM ION, protein-tyrosine phosphatase, ... | | 著者 | Erlanson, D.A, McDowell, R.S, He, M.M, Randal, M, Simmons, R.L, Kung, J, Waight, A, Hansen, S. | | 登録日 | 2003-02-06 | | 公開日 | 2003-04-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Discovery of a New Phosphotyrosine Mimetic for PTP1B Using Breakaway Tethering
J.Am.Chem.Soc., 125, 2003
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2GCT
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2CEO
 | | thyroxine-binding globulin complex with thyroxine | | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, GLYCEROL, THYROXINE-BINDING GLOBULIN | | 著者 | Zhou, A, Wei, Z, Read, R.J, Carrell, R.W. | | 登録日 | 2006-02-08 | | 公開日 | 2006-08-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Mechanism for the Carriage and Release of Thyroxine in the Blood.
Proc.Natl.Acad.Sci.USA, 103, 2006
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1UU4
 | | X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMICOLA GRISEA CEL12A IN COMPLEX WITH CELLOBIOSE | | 分子名称: | ENDO-BETA-1,4-GLUCANASE, TETRAETHYLENE GLYCOL, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Berglund, G.I, Shaw, A, Stahlberg, J, Kenne, L, Driguez, T.H, Mitchinson, C, Sandgren, M. | | 登録日 | 2003-12-15 | | 公開日 | 2004-09-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Crystal Complex Structures Reveal How Substrate is Bound in the -4 to the +2 Binding Sites of Humicola Grisea Cel12A
J.Mol.Biol., 342, 2004
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1PV8
 | | Crystal structure of a low activity F12L mutant of human porphobilinogen synthase | | 分子名称: | 3-(2-AMINOETHYL)-4-(AMINOMETHYL)HEPTANEDIOIC ACID, Delta-aminolevulinic acid dehydratase, ZINC ION | | 著者 | Breinig, S, Kervinen, J, Stith, L, Wasson, A.S, Fairman, R, Wlodawer, A, Zdanov, A, Jaffe, E.K. | | 登録日 | 2003-06-26 | | 公開日 | 2003-09-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase.
Nat.Struct.Biol., 10, 2003
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1JKN
 | | Solution Structure of the Nudix Enzyme Diadenosine Tetraphosphate Hydrolase from Lupinus angustifolius Complexed with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase | | 著者 | Fletcher, J.I, Swarbrick, J.D, Maksel, D, Gayler, K.R, Gooley, P.R. | | 登録日 | 2001-07-12 | | 公開日 | 2002-02-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of Ap(4)A hydrolase complexed with ATP-MgF(x) reveals the basis of substrate binding.
Structure, 10, 2002
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1NWE
 | | Ptp1B R47C Modified at C47 with N-[4-(2-{2-[3-(2-Bromo-acetylamino)-propionylamino]-3-hydroxy-propionylamino}-ethyl)-phenyl]-oxalamic acid | | 分子名称: | N-[4-(2-{2-[3-(2-BROMO-ACETYLAMINO)-PROPIONYLAMINO]-3-HYDROXY-PROPIONYLAMINO}-ETHYL)-PHENYL]-OXALAMIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | | 著者 | Erlanson, D.A, McDowell, R.S, He, M.M, Randal, M, Simmons, R.L, Kung, J, Waight, A, Hansen, S.K. | | 登録日 | 2003-02-06 | | 公開日 | 2003-05-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Discovery of a New Phosphotyrosine Mimetic for PTP1B Using Breakaway Tethering
J.Am.Chem.Soc., 125, 2003
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2A89
 | | Monomeric Sarcosine Oxidase: Structure of a covalently flavinylated amine oxidizing enzyme | | 分子名称: | (N5,C4A)-(ALPHA-HYDROXY-PROPANO)-3,4,4A,5-TETRAHYDRO-FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, Monomeric sarcosine oxidase, ... | | 著者 | Chen, Z.-W, Zhao, G, Martinovic, S, Jorns, M.S, Mathews, F.S. | | 登録日 | 2005-07-07 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure of the sodium borohydride-reduced N-(cyclopropyl)glycine adduct of the flavoenzyme monomeric sarcosine oxidase.
Biochemistry, 44, 2005
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1IER
 | | CUBIC CRYSTAL STRUCTURE OF NATIVE HORSE SPLEEN FERRITIN | | 分子名称: | CADMIUM ION, FERRITIN | | 著者 | Granier, T, Gallois, B, Dautant, A, Langlois D'Estaintot, B, Precigoux, G. | | 登録日 | 1996-05-28 | | 公開日 | 1997-01-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Comparison of the structures of the cubic and tetragonal forms of horse-spleen apoferritin.
Acta Crystallogr.,Sect.D, 53, 1997
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1Z30
 | | NMR structure of the apical part of stemloop D from cloverleaf 1 of bovine enterovirus 1 RNA | | 分子名称: | 5'-R(*GP*GP*CP*GP*UP*UP*CP*GP*UP*UP*AP*GP*AP*AP*CP*GP*UP*C)-3' | | 著者 | Ihle, Y, Ohlenschlager, O, Duchardt, E, Ramachandran, R, Gorlach, M. | | 登録日 | 2005-03-10 | | 公開日 | 2005-04-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A novel cGUUAg tetraloop structure with a conserved yYNMGg-type backbone conformation from cloverleaf 1 of bovine enterovirus 1 RNA
Nucleic Acids Res., 33, 2005
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1TJY
 | | Crystal Structure of Salmonella typhimurium AI-2 receptor LsrB in complex with R-THMF | | 分子名称: | (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran, sugar transport protein | | 著者 | Miller, S.T, Xavier, K.B, Campagna, S.R, Taga, M.E, Semmelhack, M.F, Bassler, B.L, Hughson, F.M. | | 登録日 | 2004-06-07 | | 公開日 | 2004-09-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2
Mol.Cell, 15, 2004
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2DJ6
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