PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

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6AAG	Crystal structure of budding yeast Atg8 complexed with the helical AIM of Hfl1. 分子名称: Transmembrane protein 184 homolog YKR051W,Autophagy-related protein 8 著者 Yamasaki, A, Noda, N.N. 登録日 2018-07-18 公開日 2018-12-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.445 Å) 主引用文献 Lipidation-independent vacuolar functions of Atg8 rely on its noncanonical interaction with a vacuole membrane protein Elife, 7, 2018
3EJS	Golgi alpha-Mannosidase II in complex with 5-substituted swainsonine analog: (5S)-5-[2'-(4-tert-butylphenyl)ethyl]-swainsonine 分子名称: (1S,2R,5S,8R,8aR)-5-[2-(4-tert-butylphenyl)ethyl]octahydroindolizine-1,2,8-triol, (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kuntz, D.A, Shea, K, Rose, D.R. 登録日 2008-09-18 公開日 2009-10-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural Investigation of the Binding of 5-Substituted Swainsonine Analogues to Golgi alpha-Mannosidase II. Chembiochem, 11, 2010
6AAF	Crystal structure of fission yeast Atg8 complexed with the helical AIM of Hfl1. 分子名称: Autophagy-related protein 8, Transmembrane protein 184 homolog C30D11.06c 著者 Yamasaki, A, Noda, N.N. 登録日 2018-07-18 公開日 2018-12-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.197 Å) 主引用文献 Lipidation-independent vacuolar functions of Atg8 rely on its noncanonical interaction with a vacuole membrane protein Elife, 7, 2018
5ZST	NifS from Hydrogenimonas thermopile in a persulfurated form 分子名称: Cysteine desulfurase 著者 Nakamura, R, Fujishiro, T, Takahashi, Y. 登録日 2018-04-29 公開日 2019-05-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
3EJT	Golgi alpha-Mannosidase II in complex with 5-substituted swainsonine analog:(5R)-5-[2'-(4-tert-butylphenyl)ethyl]-swainsonine 分子名称: (1S,2R,5R,8R,8aR)-5-[2-(4-tert-butylphenyl)ethyl]octahydroindolizine-1,2,8-triol, (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kuntz, D.A, Shea, K, Rose, D.R. 登録日 2008-09-18 公開日 2009-10-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural Investigation of the Binding of 5-Substituted Swainsonine Analogues to Golgi alpha-Mannosidase II. Chembiochem, 11, 2010
5WQK	Crystal structure of 3-Mercaptopyruvate Sulfurtransferase(3MST) in complex with compound1 分子名称: 4-methyl-2-(2-naphthalen-1-yl-2-oxidanylidene-ethyl)sulfanyl-1~{H}-pyrimidin-6-one, SODIUM ION, Sulfurtransferase 著者 Suwanai, Y, Toma-Fukai, S, Shimizu, T. 登録日 2016-11-27 公開日 2017-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide Sci Rep, 7, 2017
5HGX	Crystal Structure of Transketolase mutant - H261F from Pichia Stipitis 分子名称: PENTAETHYLENE GLYCOL, Transketolase 著者 Li, T.L, Hsu, L.J, Hsu, N.S. 登録日 2016-01-09 公開日 2017-01-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Structural and biochemical interrogation on transketolase from Pichia stipitis for new functionality Protein Eng. Des. Sel., 2016
3MWK	Q28E mutant of HERA N-terminal RecA-like domain, complex with 8-oxo-AMP 分子名称: Heat resistant RNA dependent ATPase, SULFATE ION, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate 著者 Rudolph, M.G, Klostermeier, D. 登録日 2010-05-06 公開日 2011-03-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop. Biol.Chem., 392, 2011
2P23	Crystal structure of human FGF19 分子名称: Fibroblast growth factor 19 著者 Mohammadi, M. 登録日 2007-03-06 公開日 2007-04-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol.Cell.Biol., 27, 2007
7CET	Crystal structure of D-cycloserine-bound form of cysteine desulfurase NifS from Helicobacter pylori 分子名称: (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, CHLORIDE ION, Cysteine desulfurase IscS, ... 著者 Nakamura, R, Takahashi, Y, Fujishiro, T. 登録日 2020-06-24 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
7CEQ	Crystal structure of cysteine desulfurase SufS H121A from Bacillus subtilis 分子名称: Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER 著者 Nakamura, R, Takahashi, Y, Fujishiro, T. 登録日 2020-06-24 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
7CER	Crystal structure of D-cycloserine-bound form of cysteine desulfurase SufS H121A from Bacillus subtilis 分子名称: Cysteine desulfurase SufS, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, DI(HYDROXYETHYL)ETHER, ... 著者 Nakamura, R, Takahashi, Y, Fujishiro, T. 登録日 2020-06-24 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
7CEP	Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS from Bacillus subtilis 分子名称: (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ... 著者 Nakamura, R, Yasuhiro, T, Fujishiro, T. 登録日 2020-06-24 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
7CEO	Crystal structure of PMP-bound form of cysteine desulfurase SufS from Bacillus subtilis 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER 著者 Nakamura, R, Takahashi, Y, Fujishiro, T. 登録日 2020-06-24 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
7CEU	Crystal structure of L-cycloserine-bound form of cysteine desulfurase NifS from Helicobacter pylori 分子名称: (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Cysteine desulfurase IscS, ISOPROPYL ALCOHOL 著者 Nakamura, R, Takahashi, Y, Fujishiro, T. 登録日 2020-06-24 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
7CES	Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS H121A from Bacillus subtilis 分子名称: (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER 著者 Nakamura, R, Takahashi, Y, Fujishiro, T. 登録日 2020-06-24 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
3DX3	Golgi alpha-Mannosidase II in complex with Mannostatin analog (1R,2R,3S,4R,5R)-5-aminocyclopentane-1,2,3,4-tetraol 分子名称: (1R,2R,3S,4R,5R)-5-aminocyclopentane-1,2,3,4-tetrol, (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kuntz, D.A, Rose, D.R. 登録日 2008-07-23 公開日 2009-07-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A. Chembiochem, 10, 2009
3DX0	Golgi alpha-Mannosidase II in complex with Mannostatin A at pH 5.75 分子名称: (1R,2R,3R,4S,5R)-4-AMINO-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kuntz, D.A, Rose, D.R. 登録日 2008-07-23 公開日 2009-07-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A. Chembiochem, 10, 2009
7CFZ	SH3 domain of NADPH oxidase activator 1 分子名称: NADPH oxidase activator 1 著者 Kim, M, Park, J.H, Attri, P, Lee, W. 登録日 2020-06-29 公開日 2021-07-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural modification of NADPH oxidase activator (Noxa 1) by oxidative stress: An experimental and computational study. Int.J.Biol.Macromol., 163, 2020
5XIP	Crystal Structure of Eimeria tenella Prolyl-tRNA Synthetase (EtPRS) in complex with Halofuginone 分子名称: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Jain, V, Manickam, Y, Sharma, A. 登録日 2017-04-26 公開日 2018-03-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis Structure, 25, 2017
2PYD	The crystal structure of Glycogen phosphorylase in complex with glucose at 100 K 分子名称: DIMETHYL SULFOXIDE, Glycogen phosphorylase, muscle form, ... 著者 Alexacou, K.M, Tiraidis, C, Zographos, S.E, Chrysina, E.D, Hayes, J, Oikonomakos, N.G. 登録日 2007-05-16 公開日 2008-04-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: Comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding. Proteins, 71, 2007
2PTA	PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES 分子名称: PANDINUS TOXIN K-ALPHA 著者 Tenenholz, T.C, Rogowski, R.S, Collins, J.H, Blaustein, M.P, Weber, D.J. 登録日 1996-11-26 公開日 1997-12-10 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels. Biochemistry, 36, 1997
5XOW	Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 6'A7' on the target strand 分子名称: DNA (5'-D(P*(TD)P*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), MAGNESIUM ION, RNA (5'-R(P*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*AP*CP*CP*UP*CP*G)-3'), ... 著者 Sheng, G, Wang, J, Zhao, H, Wang, Y. 登録日 2017-05-31 公開日 2017-10-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.902 Å) 主引用文献 Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes Nucleic Acids Res., 45, 2017
5X7K	Crystal structure of the nucleotide-binding domain (NBD) of LipB, a ABC transporter subunit of a type I secretion system 分子名称: Lipase B 著者 Okano, H, Angkawidjaja, C, Takano, K. 登録日 2017-02-27 公開日 2017-11-15 最終更新日 2017-12-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural Basis for the Serratia marcescens Lipase Secretion System: Crystal Structures of the Membrane Fusion Protein and Nucleotide-Binding Domain Biochemistry, 56, 2017
3H5S	Hepatitis C virus polymerase NS5B with saccharin inhibitor 分子名称: (5S)-5-tert-butyl-1-(4-fluoro-3-methylbenzyl)-4-hydroxy-3-[8-(methylsulfonyl)-1,1-dioxido-6,7,8,9-tetrahydroisothiazolo[4,5-h]isoquinolin-3-yl]-1,5-dihydro-2H-pyrrol-2-one, RNA-directed RNA polymerase 著者 Harris, S.F, Wong, A. 登録日 2009-04-22 公開日 2009-09-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides Bioorg.Med.Chem.Lett., 19, 2009

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