7CER

Crystal structure of D-cycloserine-bound form of cysteine desulfurase SufS H121A from Bacillus subtilis

Summary for 7CER

• Entry DOI: 10.2210/pdb7cer/pdb
• Descriptor: Cysteine desulfurase SufS, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, TRIETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: cysteine desulfurase, plp-dependent enzyme, cysteine metabolism, cycloserine, inhibitor, fe-s cluster biosynthesis, biosynthetic protein
• Biological source: Bacillus subtilis subsp. subtilis str. 168
• Total number of polymer chains: 1
• Total formula weight: 47109.04

Authors

Nakamura, R.,Takahashi, Y.,Fujishiro, T. (deposition date: 2020-06-24, release date: 2021-06-30, Last modification date: 2023-11-29)

• Primary citation: Nakamura, R.,Ogawa, S.,Takahashi, Y.,Fujishiro, T.; Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.; Febs J., 2022; PubMed: 35395703; DOI: 10.1111/febs.16455

Experimental method

X-RAY DIFFRACTION (2.3 Å)