5WQK

Crystal structure of 3-Mercaptopyruvate Sulfurtransferase(3MST) in complex with compound1

Summary for 5WQK

Entry DOI	10.2210/pdb5wqk/pdb
Related	5WQJ
Descriptor	Sulfurtransferase, 4-methyl-2-(2-naphthalen-1-yl-2-oxidanylidene-ethyl)sulfanyl-1~{H}-pyrimidin-6-one, SODIUM ION, ... (4 entities in total)
Functional Keywords	transferase-inhibitor complex, transferase/inhibitor
Biological source	Mus musculus (Mouse)
Total number of polymer chains	2
Total formula weight	66105.94
Authors	Suwanai, Y.,Toma-Fukai, S.,Shimizu, T. (deposition date: 2016-11-27, release date: 2017-09-06)
Primary citation	Hanaoka, K.,Sasakura, K.,Suwanai, Y.,Toma-Fukai, S.,Shimamoto, K.,Takano, Y.,Shibuya, N.,Terai, T.,Komatsu, T.,Ueno, T.,Ogasawara, Y.,Tsuchiya, Y.,Watanabe, Y.,Kimura, H.,Wang, C.,Uchiyama, M.,Kojima, H.,Okabe, T.,Urano, Y.,Shimizu, T.,Nagano, T. Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide Sci Rep, 7:40227-40227, 2017 Cited by PubMed: 28079151 DOI: 10.1038/srep40227 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation