PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

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5I62	Crystal structure of the insertion loop deletion mutant of the RNA-dependent RNA polymerase of a human picorbirnavirus 分子名称: Potential RNA-dependent RNA polymerase 著者 Collier, A.M, Guo, Y.R, Tao, Y.J. 登録日 2016-02-15 公開日 2016-03-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus. Plos Pathog., 12, 2016
5I6D	Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 5 [3-(3-(p-Tolyl)ureido) benzoic acid] 分子名称: 3-{[(4-methylphenyl)carbamoyl]amino}benzoic acid, GLYCEROL, O-phosphoserine sulfhydrylase, ... 著者 Schnell, R, Maric, S, Schneider, G. 登録日 2016-02-16 公開日 2016-08-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis. J.Med.Chem., 59, 2016
5I7A	Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 1 [3-(3-(3,4-Dichlorophenyl)ureido)benzoic acid] 分子名称: 3-{[(3,4-dichlorophenyl)carbamoyl]amino}benzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE 著者 Schnell, R, Maric, S, Schneider, G. 登録日 2016-02-17 公開日 2016-08-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis. J.Med.Chem., 59, 2016
5IT4	Crystal structure of Mycobacterium avium SerB2 mutant D343N 分子名称: MAGNESIUM ION, Phosphoserine phosphatase 著者 Shree, S, Ramachandran, R. 登録日 2016-03-16 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Crystal Structure of Mycobacterium avium SerB2 mutant D343N (MAV_3907) at pH 6.6 To be published
5IPM	SigmaS-transcription initiation complex with 4-nt nascent RNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Liu, B, Zuo, Y, Steitz, T.A. 登録日 2016-03-09 公開日 2016-03-30 最終更新日 2016-06-22 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
4M2T	Corrected Structure of Mouse P-glycoprotein bound to QZ59-SSS 分子名称: (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1A 著者 Li, J, Jaimes, K.F, Aller, S.G. 登録日 2013-08-05 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (4.35 Å) 主引用文献 Refined structures of mouse P-glycoprotein. Protein Sci., 23, 2014
5OWM	Crystal structure of human BRD4(1) bromodomain in complex with UT48 分子名称: Bromodomain-containing protein 4, [3-[(3-methylbenzotriazol-5-yl)methyl]phenyl]methanol 著者 Zhu, J, Caflisch, A. 登録日 2017-09-01 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Chemical Space Expansion of Bromodomain Ligands Guided by in Silico Virtual Couplings (AutoCouple). Acs Cent.Sci., 4, 2018
5IT0	Crystal structure of Mycobacterium avium SerB2 mutant D343N/D347N 分子名称: MAGNESIUM ION, Phosphoserine phosphatase 著者 Shree, S, Ramachandran, R. 登録日 2016-03-16 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.968 Å) 主引用文献 Crystal Structure of Mycobacterium avium SerB2 (MAV_3907) active site mutant D343N/D347N To be published
5IW8	Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 4 [5-(3-([1,1'-Biphenyl]-3-yl)ureido)-2-hydroxybenzoic acid] 分子名称: 5-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}-2-hydroxybenzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Brunner, K, Schnell, R, Schneider, G. 登録日 2016-03-22 公開日 2016-08-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis. J.Med.Chem., 59, 2016
5IXE	1.75A RESOLUTION STRUCTURE OF 5-Fluoroindole BOUND BETA-GLYCOSIDASE (W33G) FROM SULFOLOBUS SOLFATARICUS 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-fluoro-1H-indole, Beta-galactosidase, ... 著者 Lovell, S, Battaile, K.P, Mehzabeen, N, Budiardjo, S.J, Karanicolas, J. 登録日 2016-03-23 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Full and Partial Agonism of a Designed Enzyme Switch. ACS Synth Biol, 5, 2016
7KLI	Crystal Structure of Enoyl-[acyl-carrier-protein] reductase [NADH] (InhA) from Mycobacterium abscessus 分子名称: 1,2-ETHANEDIOL, Enoyl-[acyl-carrier-protein] reductase [NADH], SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-10-30 公開日 2020-11-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Efficacy and Mode of Action of a Direct Inhibitor of Mycobacterium abscessus InhA. Acs Infect Dis., 8, 2022
5SBG	The crystal structure of METP in complex with Zn at a resolution of 1.34 A. 分子名称: METP, miniaturized rubredoxin, ZINC ION 著者 Di Costanzo, L, La Gatta, S, Chino, M. 登録日 2021-08-24 公開日 2023-02-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.338 Å) 主引用文献 Designed Rubredoxin miniature in a fully artificial electron chain triggered by visible light Nat Commun, 14, 2023
5SBI	The crystal structure of METP in complex with Co at a resolution of 1.80A. 分子名称: COBALT (II) ION, METP, miniaturized rubredoxin 著者 Di Costanzo, L, La Gatta, S, Leone, L, Chino, M. 登録日 2021-08-24 公開日 2023-02-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Miniaturization process reloaded - structural and functional insights from a miniaturized rubredoxin To be published
5SBJ	The crystal structure of METP in complex with Cd at a resolution of 1.29 A. 分子名称: CADMIUM ION, METP, miniaturized rubredoxin 著者 Di Costanzo, L, La Gatta, S, Pavone, V. 登録日 2021-08-24 公開日 2023-02-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Miniaturization process reloaded - structural and functional insights from a miniaturized rubredoxin To be published
7L6C	Crystal Structure of Enoyl-[acyl-carrier-protein] reductase InhA from Mycobacterium abscessus in complex with NAD 分子名称: 1,2-ETHANEDIOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-12-23 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Efficacy and Mode of Action of a Direct Inhibitor of Mycobacterium abscessus InhA. Acs Infect Dis., 8, 2022
4LFT	Structure of alpha-elapitoxin-Dpp2d isolated from Black Mamba (Dendroaspis polylepis) venom 分子名称: Alpha-elapitoxin-Dpp2a 著者 Wang, C.I.A, Reeks, T, Lewis, R.J, Alewood, P.F, Durek, T. 登録日 2013-06-27 公開日 2014-06-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Isolation and Structural and Pharmacological Characterization of alpha-Elapitoxin-Dpp2d, an Amidated Three Finger Toxin from Black Mamba Venom. Biochemistry, 53, 2014
4L5C	Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with adenine in space group P212121 分子名称: ADENINE, GLYCEROL, S-methyl-5'-thioadenosine phosphorylase 著者 Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M. 登録日 2013-06-10 公開日 2014-06-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.075 Å) 主引用文献 Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway. Plos Negl Trop Dis, 10, 2016
5TKY	Crystal structure of the co-translational Hsp70 chaperone Ssb in the ATP-bound, open conformation 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative uncharacterized protein 著者 Gumiero, A, Gese, G.V, Weyer, F.A, Lapouge, K, Sinning, I. 登録日 2016-10-10 公開日 2016-11-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain. Nat Commun, 7, 2016
8S51	RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. 登録日 2024-02-22 公開日 2024-04-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
4L8D	Crystal structure of the H2Db in complex with the NP-N5D peptide 分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... 著者 Rossjohn, J, Gras, S. 登録日 2013-06-16 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Acute emergence and reversion of influenza A virus quasispecies within CD8(+) T cell antigenic peptides. Nat Commun, 4, 2013
7KSL	Substrate-free human mitochondrial LONP1 分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial 著者 Shin, M, Watson, E.R, Song, A.S, Mindrebo, J.T, Novick, S.R, Griffin, P, Wiseman, R.L, Lander, G.C. 登録日 2020-11-23 公開日 2020-12-09 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structures of the human LONP1 protease reveal regulatory steps involved in protease activation. Nat Commun, 12, 2021
8S52	RNA polymerase II core initially transcribing complex with an ordered RNA of 10 nt 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. 登録日 2024-02-22 公開日 2024-04-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
5JGP	Crystal structure of the nitrate/nitrite sensor NarQ fragment bound with iodide ions 分子名称: IODIDE ION, NITRATE ION, Nitrate/nitrite sensor protein NarQ 著者 Melnikov, I, Polovinkin, V, Popov, A, Gordeliy, V. 登録日 2016-04-20 公開日 2017-05-31 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Fast iodide-SAD phasing for high-throughput membrane protein structure determination. Sci Adv, 3, 2017
7KSM	Human mitochondrial LONP1 with endogenous substrate 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ... 著者 Shin, M, Watson, E.R, Song, A.S, Mindrebo, J.T, Novick, S.R, Griffin, P, Wiseman, R.L, Lander, G.C. 登録日 2020-11-23 公開日 2020-12-02 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structures of the human LONP1 protease reveal regulatory steps involved in protease activation. Nat Commun, 12, 2021
8S54	RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state b (composite structure) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Zhan, Y, Grabber, F, Oberbeckmann, E, Dienemann, C, Cramer, P. 登録日 2024-02-22 公開日 2024-04-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024

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