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2NVC
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Human Aldose Reductase complexed with novel naphtho[1,2-d]isothiazole acetic acid derivative (3)
分子名称: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID
著者Steuber, H, Heine, A, Klebe, G.
登録日2006-11-12
公開日2007-04-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Evidence for a novel binding site conformer of aldose reductase in ligand-bound state
J.Mol.Biol., 369, 2007
2NVD
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Human Aldose Reductase complexed with novel naphtho[1,2-d]isothiazole acetic acid derivative (2)
分子名称: 2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Steuber, H, Heine, A, Klebe, G.
登録日2006-11-12
公開日2007-04-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Evidence for a novel binding site conformer of aldose reductase in ligand-bound state
J.Mol.Biol., 369, 2007
2NVE
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Soluble domain of Rieske Iron Sulfur Protein
分子名称: FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, Ubiquinol-cytochrome c reductase iron-sulfur subunit
著者Kolling, D.K, Brunzelle, J.S, Lhee, S, Crofts, A.R, Nair, S.K.
登録日2006-11-12
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Atomic resolution structures of rieske iron-sulfur protein: role of hydrogen bonds in tuning the redox potential of iron-sulfur clusters.
Structure, 15, 2007
2NVF
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Soluble domain of Rieske Iron-Sulfur protein.
分子名称: FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, Ubiquinol-cytochrome c reductase iron-sulfur subunit
著者Kolling, D, Brunzelle, J, Lhee, S, Crofts, A.R, Nair, S.K.
登録日2006-11-12
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Atomic resolution structures of rieske iron-sulfur protein: role of hydrogen bonds in tuning the redox potential of iron-sulfur clusters.
Structure, 15, 2007
2NVG
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Soluble domain of Rieske Iron Sulfur protein.
分子名称: FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, Ubiquinol-cytochrome c reductase iron-sulfur subunit
著者Kolling, D, Brunzelle, J, Lhee, S, Crofts, A.R, Nair, S.K.
登録日2006-11-12
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Atomic resolution structures of rieske iron-sulfur protein: role of hydrogen bonds in tuning the redox potential of iron-sulfur clusters.
Structure, 15, 2007
2NVH
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Determination of Solvent Content in Cavities in Interleukin-1 Using Experimentally-Phased Electron Density
分子名称: Interleukin-1 beta, SULFATE ION
著者Quillin, M.L, Matthews, B.W.
登録日2006-11-12
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Determination of solvent content in cavities in IL-1beta using experimentally phased electron density
Proc.Natl.Acad.Sci.Usa, 103, 2006
2NVJ
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NMR structures of transmembrane segment from subunit a from the yeast proton V-ATPase
分子名称: 25mer peptide from Vacuolar ATP synthase subunit a, vacuolar isoform
著者Hemminga, M.A, van Mierlo, C.P, Wechselberger, R, de Jong, E.R, Duarte, A.M.
登録日2006-11-13
公開日2007-10-02
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Segment TM7 from the cytoplasmic hemi-channel from V(O)-H(+)-V-ATPase includes a flexible region that has a potential role in proton translocation
Biochim.Biophys.Acta, 1768, 2007
2NVK
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Crystal Structure of Thioredoxin Reductase from Drosophila melanogaster
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin Reductase
著者Eckenroth, B.E, Rould, M.A, Hondal, R.J, Everse, S.J.
登録日2006-11-13
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Biochemical Studies Reveal Differences in the Catalytic Mechanisms of Mammalian and Drosophila melanogaster Thioredoxin Reductases.
Biochemistry, 46, 2007
2NVL
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Crystal structure of archaeal peroxiredoxin, thioredoxin peroxidase from Aeropyrum pernix K1 (sulfonic acid form)
分子名称: Probable peroxiredoxin
著者Nakamura, T, Yamamoto, T, Abe, M, Matsumura, H, Hagihara, Y, Goto, T, Yamaguchi, T, Inoue, T.
登録日2006-11-13
公開日2007-11-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
Proc.Natl.Acad.Sci.Usa, 105, 2008
2NVM
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Crystal structure of fdxN element excision controlling factor XisI (YP_321976.1) from Anabaena Variabilis ATCC 29413 at 2.19 A resolution
分子名称: FdxN element excision controlling factor XisI
著者Joint Center for Structural Genomics (JCSG)
登録日2006-11-13
公開日2006-12-12
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Site-specific recombination of nitrogen-fixation genes in cyanobacteria by XisF-XisH-XisI complex: Structures and models.
Proteins, 2014
2NVN
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Crystal structure of a protein with a cupin-like fold and unknown function (YP_400729.1) from Synechococcus SP. PCC 7942 (Elongatus) at 2.50 A resolution
分子名称: GLYCEROL, Hypothetical protein
著者Joint Center for Structural Genomics (JCSG)
登録日2006-11-13
公開日2006-12-12
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of hypothetical protein (YP_400729.1) from Synechococcus SP. PCC 7942 (Elongatus) at 2.50 A resolution
To be published
2NVO
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Crystal structure of Deinococcus radiodurans RO (RSR) protein
分子名称: CALCIUM ION, Ro sixty-related protein, RSR
著者Ramesh, A, Sacchettini, J.C.
登録日2006-11-13
公開日2007-03-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal structure of Rsr, an ortholog of the antigenic Ro protein, links conformational flexibility to RNA binding activity.
J.Biol.Chem., 282, 2007
2NVP
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X-Ray Crystal Structure of Protein CPF_0428 from Clostridium perfringens. Northeast Structural Genomics Consortium Target CpR63.
分子名称: Hypothetical protein
著者Forouhar, F, Chen, Y, Seetharaman, J, Cunningham, K, Ma, L.-C, Fang, Y, Baran, M.C, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2006-11-13
公開日2006-11-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Hypothetical Protein CPF_0428 from Clostridium perfringens, Northeast Structural Genomics Target CpR63.
TO BE PUBLISHED
2NVQ
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RNA Polymerase II Elongation Complex in 150 mM Mg+2 with 2'dUTP
分子名称: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
著者Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
登録日2006-11-13
公開日2006-12-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2NVT
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RNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPP
分子名称: 5'-D(*GP*TP*AP*CP*TP*TP*G)-3', 5'-D(P*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ...
著者Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
登録日2006-11-13
公開日2006-12-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2NVU
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Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltose binding protein/NEDD8-activating enzyme E1 catalytic subunit chimera, ...
著者Huang, D.T, Hunt, H.W, Zhuang, M, Ohi, M.D, Holton, J.M, Schulman, B.A.
登録日2006-11-13
公開日2007-01-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
Nature, 445, 2007
2NVV
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Crystal Structure of the Putative Acetyl-CoA hydrolase/transferase PG1013 from Porphyromonas gingivalis, Northeast Structural Genomics Target PgR16.
分子名称: Acetyl-CoA hydrolase/transferase family protein, ZINC ION
著者Forouhar, F, Neely, H, Seetharaman, J, Yong, W, Ho, C.K, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2006-11-13
公開日2007-01-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of the Putative Acetyl-CoA hydrolase/transferase PG1013 from Porphyromonas gingivalis, Northeast Structural Genomics Target PgR16
To be Published
2NVW
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Crystal sctucture of transcriptional regulator Gal80p from kluyveromymes lactis
分子名称: Galactose/lactose metabolism regulatory protein GAL80
著者Thoden, J.B, Sellick, C.A, Reece, R.J, Holden, H.M.
登録日2006-11-13
公開日2006-11-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Understanding a transcriptional paradigm at the molecular level. The structure of yeast Gal80p.
J.Biol.Chem., 282, 2007
2NVX
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RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP
分子名称: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
著者Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
登録日2006-11-13
公開日2006-12-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2NVY
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RNA Polymerase II form II in 150 mM Mn+2
分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 45 kDa polypeptide, ...
著者Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
登録日2006-11-13
公開日2006-12-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2NVZ
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RNA Polymerase II elongation complex with UTP, updated 11/2006
分子名称: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
著者Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
登録日2006-11-14
公開日2006-12-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2NW0
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Crystal structure of a lysin
分子名称: ACETATE ION, PlyB
著者Porter, C.J, Buckle, A.M, Whisstock, J.C.
登録日2006-11-14
公開日2006-12-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The 1.6 A Crystal Structure of the Catalytic Domain of PlyB, a Bacteriophage Lysin Active Against Bacillus anthracis.
J.Mol.Biol., 366, 2007
2NW2
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Crystal structure of ELS4 TCR at 1.4A
分子名称: ELS4 TCR alpha chain, ELS4 TCR beta chain
著者Tynan, F.E, Reid, H.H, Rossjohn, J.
登録日2006-11-14
公開日2007-02-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Nat.Immunol., 8, 2007
2NW3
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Crystal structure of HLA-B*3508 presenting EBV peptide EPLPQGQLTAY at 1.7A
分子名称: Beta-2-microglobulin, EBV peptide EPLPQGQLTAY, HLA class I histocompatibility antigen, ...
著者Tynan, F.E, Reid, H.H, Rossjohn, J.
登録日2006-11-14
公開日2007-02-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Nat.Immunol., 8, 2007
2NW4
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Crystal Structure of the Rat Androgen Receptor Ligand Binding Domain Complex with BMS-564929
分子名称: 2-CHLORO-4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-3-METHYLBENZONITRILE, Androgen receptor
著者Ostrowski, J, Kuhns, J.E, Lupisella, J.A, Manfredi, M.C, Beehler, B.C, Krystek, S.R, Bi, Y, Sun, C, Seethala, R, Golla, R, Sleph, P.G, Fura, A, An, Y, Kish, K.F, Sack, J.S, Mookhtiar, K.A, Grover, G.J, Hamann, L.G.
登録日2006-11-14
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Pharmacological and x-ray structural characterization of a novel selective androgen receptor modulator: potent hyperanabolic stimulation of skeletal muscle with hypostimulation of prostate in rats.
Endocrinology, 148, 2007

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