Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2NW4

Crystal Structure of the Rat Androgen Receptor Ligand Binding Domain Complex with BMS-564929

Summary for 2NW4
Entry DOI10.2210/pdb2nw4/pdb
DescriptorAndrogen receptor, 2-CHLORO-4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-3-METHYLBENZONITRILE (3 entities in total)
Functional Keywordsandrogen receptor, steroid receptor, nuclear receptor, transcription regulation, ligand-binding domain, hormone-growth factor complex, hormone/growth factor
Biological sourceRattus norvegicus (Norway rat)
Cellular locationNucleus: P15207
Total number of polymer chains1
Total formula weight30588.13
Authors
Primary citationOstrowski, J.,Kuhns, J.E.,Lupisella, J.A.,Manfredi, M.C.,Beehler, B.C.,Krystek, S.R.,Bi, Y.,Sun, C.,Seethala, R.,Golla, R.,Sleph, P.G.,Fura, A.,An, Y.,Kish, K.F.,Sack, J.S.,Mookhtiar, K.A.,Grover, G.J.,Hamann, L.G.
Pharmacological and x-ray structural characterization of a novel selective androgen receptor modulator: potent hyperanabolic stimulation of skeletal muscle with hypostimulation of prostate in rats.
Endocrinology, 148:4-12, 2007
Cited by
PubMed: 17008401
DOI: 10.1210/en.2006-0843
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon