PDB: 452 件ウェブページステータス検索Chemie searchBIRD

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1QPF	FK506 BINDING PROTEIN (12 KDA, HUMAN) COMPLEX WITH L-709,858 分子名称: C32-O-(1-ETHYL-INDOL-5-YL)ASCOMYCIN, PROTEIN (FK506-BINDING PROTEIN), heptyl beta-D-glucopyranoside 著者 Becker, J.W, Rotonda, J. 登録日 1999-05-24 公開日 1999-08-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein. J.Med.Chem., 42, 1999
1QPL	FK506 BINDING PROTEIN (12 KDA, HUMAN) COMPLEX WITH L-707,587 分子名称: C32-O-(1-METHYL-INDOL-5-YL) 18-HYDROXY-ASCOMYCIN, PROTEIN (FK506-BINDING PROTEIN) 著者 Becker, J.W, Rotonda, J. 登録日 1999-05-25 公開日 1999-08-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein. J.Med.Chem., 42, 1999
1B6C	CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF THE TYPE I TGF-BETA RECEPTOR IN COMPLEX WITH FKBP12 分子名称: FK506-BINDING PROTEIN, SULFATE ION, TGF-B SUPERFAMILY RECEPTOR TYPE I 著者 Huse, M, Chen, Y.-G, Massague, J, Kuriyan, J. 登録日 1999-01-13 公開日 1999-06-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12. Cell(Cambridge,Mass.), 96, 1999
2FAP	THE STRUCTURE OF THE IMMUNOPHILIN-IMMUNOSUPPRESSANT FKBP12-(C16)-ETHOXY RAPAMYCIN COMPLEX INTERACTING WITH HUMA 分子名称: C49-METHYL RAPAMYCIN, FK506-BINDING PROTEIN, FRAP 著者 Liang, J, Choi, J, Clardy, J. 登録日 1998-09-22 公開日 1999-05-18 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution. Acta Crystallogr.,Sect.D, 55, 1999
1BL4	FKBP MUTANT F36V COMPLEXED WITH REMODELED SYNTHETIC LIGAND 分子名称: PROTEIN (FK506 BINDING PROTEIN), {3-[3-(3,4-DIMETHOXY-PHENYL)-1-(1-{1-[2-(3,4,5-TRIMETHOXY-PHENYL)-BUTYRYL]-PIPERIDIN-2YL}-VINYLOXY)-PROPYL]-PHENOXY}-ACETIC ACID 著者 Hatada, M.H, Clackson, T, Yang, W, Rozamus, L.W, Amara, J, Rollins, C.T, Stevenson, L.F, Magari, S.R, Wood, S.A, Courage, N.L, Lu, X, Cerasoli Junior, F, Gilman, M, Holt, D. 登録日 1998-07-23 公開日 1998-09-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity. Proc.Natl.Acad.Sci.USA, 95, 1998
1A7X	FKBP12-FK1012 COMPLEX 分子名称: BENZYL-CARBAMIC ACID [8-DEETHYL-ASCOMYCIN-8-YL]ETHYL ESTER, FKBP12 著者 Schultz, L.W, Clardy, J. 登録日 1998-03-18 公開日 1998-06-17 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Chemical inducers of dimerization: the atomic structure of FKBP12-FK1012A-FKBP12. Bioorg.Med.Chem.Lett., 8, 1998
1NSG	THE STRUCTURE OF THE IMMUNOPHILIN-IMMUNOSUPPRESSANT FKBP12-RAPAMYCIN COMPLEX INTERACTING WITH HUMAN FRAP 分子名称: C49-METHYL RAPAMYCIN, FK506-BINDING PROTEIN, FKBP-RAPAMYCIN ASSOCIATED PROTEIN (FRAP) 著者 Liang, J, Choi, J, Clardy, J. 登録日 1997-07-01 公開日 1998-03-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution. Acta Crystallogr.,Sect.D, 55, 1999
1FAP	THE STRUCTURE OF THE IMMUNOPHILIN-IMMUNOSUPPRESSANT FKBP12-RAPAMYCIN COMPLEX INTERACTING WITH HUMAN FRAP 分子名称: FK506-BINDING PROTEIN, FRAP, RAPAMYCIN IMMUNOSUPPRESSANT DRUG 著者 Choi, J, Chen, J, Schreiber, S.L, Clardy, J. 登録日 1996-03-15 公開日 1997-07-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP. Science, 273, 1996
1TCO	TERNARY COMPLEX OF A CALCINEURIN A FRAGMENT, CALCINEURIN B, FKBP12 AND THE IMMUNOSUPPRESSANT DRUG FK506 (TACROLIMUS) 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, FE (III) ION, ... 著者 Griffith, J.P, Kim, J.L, Kim, E.E, Sintchak, M.D, Thomson, J.A, Fitzgibbon, M.J, Fleming, M.A, Caron, P.R, Hsiao, K, Navia, M.A. 登録日 1996-08-21 公開日 1997-02-12 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex. Cell(Cambridge,Mass.), 82, 1995
1ROT	STRUCTURE OF FKBP59-I, THE N-TERMINAL DOMAIN OF A 59 KDA FK506-BINDING PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: FKBP59-I 著者 Craescu, C.T, Rouviere, N, Popescu, A, Cerpolini, E, Lebeau, M.-C, Baulieu, E.-E, Mispelter, J. 登録日 1996-06-14 公開日 1996-12-07 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Three-dimensional structure of the immunophilin-like domain of FKBP59 in solution. Biochemistry, 35, 1996
1ROU	STRUCTURE OF FKBP59-I, THE N-TERMINAL DOMAIN OF A 59 KDA FK506-BINDING PROTEIN, NMR, 22 STRUCTURES 分子名称: FKBP59-I 著者 Craescu, C.T, Rouviere, N, Popescu, A, Cerpolini, E, Lebeau, M.-C, Baulieu, E.-E, Mispelter, J. 登録日 1996-06-14 公開日 1996-12-07 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Three-dimensional structure of the immunophilin-like domain of FKBP59 in solution. Biochemistry, 35, 1996
1PBK	HOMOLOGOUS DOMAIN OF HUMAN FKBP25 分子名称: FKBP25, RAPAMYCIN IMMUNOSUPPRESSANT DRUG 著者 Liang, J, Hung, D.T, Schreiber, S.L, Clardy, J. 登録日 1995-09-01 公開日 1996-10-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the human 25 kDa FK506 binding protein complexed with rapamycin. J.Am.Chem.Soc., 118, 1996
1BKF	FK506 BINDING PROTEIN FKBP MUTANT R42K/H87V COMPLEX WITH IMMUNOSUPPRESSANT FK506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506 BINDING PROTEIN 著者 Itoh, S, Decenzo, M.T, Livingston, D.J, Pearlman, D.A, Navia, M.A. 登録日 1995-10-18 公開日 1996-08-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Conformation of Fk506 in X-Ray Structures of its Complexes with Human Recombinant Fkbp12 Mutants Bioorg.Med.Chem.Lett., 5, 1995
1FKJ	ATOMIC STRUCTURE OF FKBP12-FK506, AN IMMUNOPHILIN IMMUNOSUPPRESSANT COMPLEX 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506 BINDING PROTEIN 著者 Wilson, K.P, Sintchak, M.D, Thomson, J.A, Navia, M.A. 登録日 1995-08-18 公開日 1995-12-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comparative X-ray structures of the major binding protein for the immunosuppressant FK506 (tacrolimus) in unliganded form and in complex with FK506 and rapamycin. Acta Crystallogr.,Sect.D, 51, 1995
1FKL	ATOMIC STRUCTURE OF FKBP12-RAPAYMYCIN, AN IMMUNOPHILIN-IMMUNOSUPPRESSANT COMPLEX 分子名称: FK506 BINDING PROTEIN, RAPAMYCIN IMMUNOSUPPRESSANT DRUG 著者 Wilson, K.P, Sintchak, M.D, Thomson, J.A, Navia, M.A. 登録日 1995-08-18 公開日 1995-12-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comparative X-ray structures of the major binding protein for the immunosuppressant FK506 (tacrolimus) in unliganded form and in complex with FK506 and rapamycin. Acta Crystallogr.,Sect.D, 51, 1995
1FKK	ATOMIC STRUCTURE OF FKBP12, AN IMMUNOPHILIN BINDING PROTEIN 分子名称: FK506 BINDING PROTEIN, SULFATE ION 著者 Wilson, K.P, Sintchak, M.D, Thomson, J.A, Navia, M.A. 登録日 1995-08-18 公開日 1995-12-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Comparative X-ray structures of the major binding protein for the immunosuppressant FK506 (tacrolimus) in unliganded form and in complex with FK506 and rapamycin. Acta Crystallogr.,Sect.D, 51, 1995
1FKG	DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS, AND THE X-RAY CRYSTAL STRUCTURES OF THEIR COMPLEXES WITH FKBP12 分子名称: 1,3-DIPHENYL-1-PROPYL-1-(3,3-DIMETHYL-1,2-DIOXYPENTYL)-2-PIPERIDINE CARBOXYLATE, FK506 BINDING PROTEIN 著者 Holt, D.A, Luengo, J.I, Yamashita, D.S, Oh, H.-J, Konialian, A.L, Yen, H.-K, Rozamus, L.W, Brandt, M, Bossard, M.J, Levy, M.A, Eggleston, D.S, Stout, T.J, Liang, J, Schultz, L.W, Clardy, J. 登録日 1993-08-05 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS AND THE X-RAY CRYSTAL-STRUCTURES OF THEIR COMPLEXES WITH FKBP12. J.Am.Chem.Soc., 115, 1993
1FKS	SOLUTION STRUCTURE OF FKBP, A ROTAMASE ENZYME AND RECEPTOR FOR FK506 AND RAPAMYCIN 分子名称: FK506 AND RAPAMYCIN-BINDING PROTEIN 著者 Michnick, S.W, Rosen, M.K, Wandless, T.J, Karplus, M, Schreiber, S.L. 登録日 1992-03-05 公開日 1994-01-31 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin. Science, 252, 1991
1FKH	DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS, AND THE X-RAY CRYSTAL STRUCTURES OF THEIR COMPLEXES WITH FKBP12 分子名称: 1-CYCLOHEXYL-3-PHENYL-1-PROPYL-1-(3,3-DIMETHYL-1,2-DIOXYPENTYL)-2-PIPERIDINE CARBOXYLATE, FK506 BINDING PROTEIN 著者 Holt, D.A, Luengo, J.I, Yamashita, D.S, Oh, H.-J, Konialian, A.L, Yen, H.-K, Rozamus, L.W, Brandt, M, Bossard, M.J, Levy, M.A, Eggleston, D.S, Stout, T.J, Liang, J, Schultz, L.W, Clardy, J. 登録日 1993-08-05 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS AND THE X-RAY CRYSTAL-STRUCTURES OF THEIR COMPLEXES WITH FKBP12. J.Am.Chem.Soc., 115, 1993
1FKI	DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS, AND THE X-RAY CRYSTAL STRUCTURES OF THEIR COMPLEXES WITH FKBP12 分子名称: (21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE, FK506 BINDING PROTEIN 著者 Holt, D.A, Luengo, J.I, Yamashita, D.S, Oh, H.-J, Konialian, A.L, Yen, H.-K, Rozamus, L.W, Brandt, M, Bossard, M.J, Levy, M.A, Eggleston, D.S, Stout, T.J, Liang, J, Schultz, L.W, Clardy, J. 登録日 1993-08-05 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS AND THE X-RAY CRYSTAL-STRUCTURES OF THEIR COMPLEXES WITH FKBP12. J.Am.Chem.Soc., 115, 1993
1FKT	SOLUTION STRUCTURE OF FKBP, A ROTAMASE ENZYME AND RECEPTOR FOR FK506 AND RAPAMYCIN 分子名称: FK506 AND RAPAMYCIN-BINDING PROTEIN 著者 Michnick, S.W, Rosen, M.K, Wandless, T.J, Karplus, M, Schreiber, S.L. 登録日 1992-03-05 公開日 1994-01-31 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin. Science, 252, 1991
1FKR	SOLUTION STRUCTURE OF FKBP, A ROTAMASE ENZYME AND RECEPTOR FOR FK506 AND RAPAMYCIN 分子名称: FK506 AND RAPAMYCIN-BINDING PROTEIN 著者 Michnick, S.W, Rosen, M.K, Wandless, T.J, Karplus, M, Schreiber, S.L. 登録日 1992-03-05 公開日 1994-01-31 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin. Science, 252, 1991
1FKD	FK-506 BINDING PROTEIN: THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX WITH THE ANTAGONIST L-685,818 分子名称: 18-HYDROXYASCOMYCIN, FK506 BINDING PROTEIN 著者 Becker, J.W, Rotonda, J, Mckeever, B.M. 登録日 1992-12-02 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818. J.Biol.Chem., 268, 1993
2FKE	FK-506-BINDING PROTEIN: THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX WITH THE ANTAGONIST L-685,818 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506 BINDING PROTEIN 著者 Becker, J.W, Mckeever, B.M, Rotonda, J. 登録日 1993-01-27 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818. J.Biol.Chem., 268, 1993
1FKB	ATOMIC STRUCTURE OF THE RAPAMYCIN HUMAN IMMUNOPHILIN FKBP-12 COMPLEX 分子名称: FK506 BINDING PROTEIN, RAPAMYCIN IMMUNOSUPPRESSANT DRUG 著者 Van Duyne, G.D, Standaert, R.F, Schreiber, S.L, Clardy, J.C. 登録日 1992-07-02 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Atomic Structure of the Rapamycin Human Immunophilin Fkbp-12 Complex J.Am.Chem.Soc., 113, 1991

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