1J4R
FK506 BINDING PROTEIN COMPLEXED WITH FKB-001
Summary for 1J4R
Entry DOI | 10.2210/pdb1j4r/pdb |
Descriptor | FK506-BINDING PROTEIN, 1-[2,2-DIFLUORO-2-(3,4,5-TRIMETHOXY-PHENYL)-ACETYL]-PIPERIDINE-2-CARBOXYLIC ACID 4-PHENYL-1-(3-PYRIDIN-3-YL-PROPYL)-BUTYL ESTER, GLYCEROL, ... (5 entities in total) |
Functional Keywords | rotamase, inhibitor, isomerase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol : P62942 |
Total number of polymer chains | 3 |
Total formula weight | 37667.89 |
Authors | Sheriff, S. (deposition date: 2001-10-29, release date: 2001-12-19, Last modification date: 2023-08-16) |
Primary citation | Dubowchik, G.M.,Vrudhula, V.M.,Dasgupta, B.,Ditta, J.,Chen, T.,Sheriff, S.,Sipman, K.,Witmer, M.,Tredup, J.,Vyas, D.M.,Verdoorn, T.A.,Bollini, S.,Vinitsky, A. 2-Aryl-2,2-difluoroacetamide FKBP12 ligands: synthesis and X-ray structural studies. Org.Lett., 3:3987-3990, 2001 Cited by PubMed: 11735566DOI: 10.1021/ol0166909 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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