PDB: 11109 件ウェブページステータス検索Chemie searchBIRD

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6QOB	Crystal structure of ribonucleotide reductase NrdF from Bacillus anthracis with partially oxidised di-iron metallocofactor 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (III) ION, Ribonucleoside-diphosphate reductase subunit beta, ... 著者 Grave, K, Hogbom, M. 登録日 2019-02-12 公開日 2019-08-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.457 Å) 主引用文献 Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access. J.Biol.Inorg.Chem., 24, 2019
6M5Y	Structure of human galectin-1 tandem-repeat mutant with lactose 分子名称: Galectin-1,Galectin-1, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose 著者 Nonaka, Y, Kamitori, S, Nakamura, T. 登録日 2020-03-12 公開日 2021-03-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Crystal structure and conformational stability of a galectin-1 tandem-repeat mutant with a short linker. Glycobiology, 2021
6T0G	Crystal structure of CYP124 in complex with vitamin D3 分子名称: (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLI DENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL, MAGNESIUM ION, Methyl-branched lipid omega-hydroxylase, ... 著者 Bukhdruker, S, Marin, E, Varaksa, T, Gilep, A, Strushkevich, N, Borshchevskiy, V. 登録日 2019-10-03 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Metabolic Fate of Human Immunoactive Sterols in Mycobacterium tuberculosis. J.Mol.Biol., 433, 2021
6SU4	Crystal structure of the 48C12 heliorhodopsin in the blue form at pH 4.3 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 48C12 heliorhodopsin, ACETATE ION, ... 著者 Kovalev, K, Volkov, D, Astashkin, R, Alekseev, A, Gushchin, I, Gordeliy, V. 登録日 2019-09-12 公開日 2019-12-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High-resolution structural insights into the heliorhodopsin family. Proc.Natl.Acad.Sci.USA, 117, 2020
6T0H	Crystal structure of CYP124 in complex with 1-alpha-hydroxy-vitamin D3 分子名称: 1-alpha-hydroxy-vitamin D3, CHLORIDE ION, CYP124 in complex with inhibitor carbethoxyhexyl imidazole, ... 著者 Bukhdruker, S, Marin, E, Varaksa, T, Gilep, A, Strushkevich, N, Borshchevskiy, V. 登録日 2019-10-03 公開日 2020-10-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 Metabolic Fate of Human Immunoactive Sterols in Mycobacterium tuberculosis. J.Mol.Biol., 433, 2021
1GD6	STRUCTURE OF THE BOMBYX MORI LYSOZYME 分子名称: LYSOZYME 著者 Matsuura, A, Aizawa, T, Yao, M, Kawano, K, Tanaka, I, Nitta, K. 登録日 2000-09-19 公開日 2001-03-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural analysis of an insect lysozyme exhibiting catalytic efficiency at low temperatures. Biochemistry, 41, 2002
6IO0	Human IDH1 R132C mutant complexed with compound A. 分子名称: (2E)-3-{3-[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazole-4-carbonyl]-1-methyl-1H-indol-7-yl}prop-2-enoic acid, CITRIC ACID, GLYCEROL, ... 著者 Suzuki, M, Baba, D, Hanzawa, H. 登録日 2018-10-29 公開日 2019-10-30 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model. Mol.Cancer Ther., 19, 2020
6T0K	Crystal structure of CYP124 in complex with inhibitor carbethoxyhexyl imidazole 分子名称: CHLORIDE ION, CYP124 in complex with inhibitor carbethoxyhexyl imidazole, GLYCEROL, ... 著者 Bukhdruker, S, Marin, E, Varaksa, T, Gilep, A, Strushkevich, N, Borshchevskiy, V. 登録日 2019-10-03 公開日 2020-10-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 Metabolic Fate of Human Immunoactive Sterols in Mycobacterium tuberculosis. J.Mol.Biol., 433, 2021
8C8J	Long Interspersed Nuclear Element 1 (LINE-1) reverse transcriptase ternary complex with hybrid duplex and dTTP 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, CHLORIDE ION, ... 著者 Nichols, C.E, Walpole, T.B, Baldwin, E. 登録日 2023-01-20 公開日 2023-12-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626, 2024
8DS6	Structure of the PEAK3 pseudokinase homodimer 分子名称: Protein PEAK3 著者 Torosyan, H, Paul, M, Jura, N, Verba, K.A. 登録日 2022-07-21 公開日 2023-06-28 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3. Nat Commun, 14, 2023
6T0L	Crystal structure of CYP124 in complex with inhibitor compound 5' 分子名称: CHLORIDE ION, CYP124 in complex with inhibitor compound 5', DI(HYDROXYETHYL)ETHER, ... 著者 Bukhdruker, S, Marin, E, Varaksa, T, Gilep, A, Strushkevich, N, Borshchevskiy, V. 登録日 2019-10-03 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Metabolic Fate of Human Immunoactive Sterols in Mycobacterium tuberculosis. J.Mol.Biol., 433, 2021
6SB0	cryo-EM structure of mTORC1 bound to PRAS40-fused active RagA/C GTPases 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Proline-rich AKT1 substrate 1, ... 著者 Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L. 登録日 2019-07-18 公開日 2019-10-16 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (5.5 Å) 主引用文献 Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
6MPV	Cryo-electron microscopy structure of Plasmodium falciparum Rh5/CyRPA/Ripr invasion complex 分子名称: Cysteine-rich protective antigen, PfRipr, Reticulocyte binding protein 5 著者 Wilson, W, Zhiheng, Y, Cowman, A.F. 登録日 2018-10-08 公開日 2018-12-12 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (7.17 Å) 主引用文献 Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex. Nature, 565, 2019
6IPA	C-terminal EMAP II-like domain of p43 refined against twinned data 分子名称: aminoacyl-tRNA synthetase-interacting multifunctional protein p43 著者 Manickam, Y, Harlos, K, Gupta, S, Sharma, A. 登録日 2018-11-02 公開日 2019-11-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Crystal structures of the two domains that constitute the Plasmodium vivax p43 protein. Acta Crystallogr D Struct Biol, 76, 2020
8EW6	Anti-human CD8 VHH complex with CD8 alpha 分子名称: Anti-CD8 alpha VHH, T-cell surface glycoprotein CD8 alpha chain 著者 Kiefer, J.R, Williams, S, Davies, C.W, Koerber, J.T, Sriraman, S.K, Yin, Y.P. 登録日 2022-10-21 公開日 2022-11-23 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.904 Å) 主引用文献 Development of an 18 F-labeled anti-human CD8 VHH for same-day immunoPET imaging. Eur J Nucl Med Mol Imaging, 50, 2023
6IZN	Crystal structure of the PPARgamma-LBD complexed with compound 3g 分子名称: 3-[[6-(2,6-dimethylpyridin-3-yl)oxy-7-fluoranyl-1-methyl-benzimidazol-2-yl]methoxy]benzoic acid, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, Peroxisome proliferator-activated receptor gamma 著者 Matsui, Y, Hanzawa, H. 登録日 2018-12-20 公開日 2019-03-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-Activity Relationship Studies of 3- or 4-Pyridine Derivatives of DS-6930. Acs Med.Chem.Lett., 10, 2019
6M26	Sirohydrochlorin nickelochelatase CfbA in P212121 space group 分子名称: Sirohydrochlorin cobaltochelatase 著者 Fujishiro, T. 登録日 2020-02-26 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 The nickel-sirohydrochlorin formation mechanism of the ancestral class II chelatase CfbA in coenzyme F430 biosynthesis. Chem Sci, 12, 2021
6M29	Sirohydrochlorin nickelochelatase CfbA in complex with Co2+ and formate 分子名称: COBALT (II) ION, FORMIC ACID, Sirohydrochlorin cobaltochelatase 著者 Fujishiro, T. 登録日 2020-02-26 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The nickel-sirohydrochlorin formation mechanism of the ancestral class II chelatase CfbA in coenzyme F430 biosynthesis. Chem Sci, 12, 2021
6SU3	Crystal structure of the 48C12 heliorhodopsin in the violet form at pH 8.8 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 48C12 heliorhodopsin, EICOSANE, ... 著者 Kovalev, K, Volkov, D, Astashkin, R, Alekseev, A, Gushchin, I, Gordeliy, V. 登録日 2019-09-12 公開日 2019-12-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High-resolution structural insights into the heliorhodopsin family. Proc.Natl.Acad.Sci.USA, 117, 2020
8CQO	Crystal structure of Borrelia burgdorferi paralogous family 12 outer surface protein BBK01 (Se-Met data) 分子名称: Lipoprotein, putative 著者 Brangulis, K, Drunka, L, Matisone, S, Akopjana, I, Tars, K. 登録日 2023-03-06 公開日 2024-03-13 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Members of the paralogous gene family 12 from the Lyme disease agent Borrelia burgdorferi are non-specific DNA-binding proteins. Plos One, 19, 2024
8CQN	Crystal structure of Borrelia burgdorferi paralogous family 12 outer surface protein BBK01 分子名称: Lipoprotein, putative 著者 Brangulis, K, Drunka, L, Matisone, S, Akopjana, I, Tars, K. 登録日 2023-03-06 公開日 2024-03-13 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Members of the paralogous gene family 12 from the Lyme disease agent Borrelia burgdorferi are non-specific DNA-binding proteins. Plos One, 19, 2024
6MFP	Crystal Structure of the RV305 C1-C2 specific ADCC potent antibody DH677.3 Fab in complex with HIV-1 clade A/E gp120 and M48U1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 Tolbert, W.D, Young, B, Pazgier, M. 登録日 2018-09-11 公開日 2019-09-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency. J.Virol., 94, 2020
6T0F	Crystal structure of CYP124 in complex with cholest-4-en-3-one 分子名称: (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, ... 著者 Bukhdruker, S, Marin, E, Varaksa, T, Gilep, A, Strushkevich, N, Borshchevskiy, V. 登録日 2019-10-03 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Metabolic Fate of Human Immunoactive Sterols in Mycobacterium tuberculosis. J.Mol.Biol., 433, 2021
6HGC	Structure of Calypso in complex with DEUBAD of ASX 分子名称: Polycomb protein Asx, Ubiquitin carboxyl-terminal hydrolase calypso,Ubiquitin carboxyl-terminal hydrolase calypso 著者 De, I, Chittock, E.C, Groetsch, H, Miller, T.C.R, McCarthy, A.A, Mueller, C.W. 登録日 2018-08-23 公開日 2019-01-23 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Structural Basis for the Activation of the Deubiquitinase Calypso by the Polycomb Protein ASX. Structure, 27, 2019
6HI9	PI3 Kinase Delta in complex with 3[6(oxan4yl)pyridin2yl]phenol 分子名称: 3-[6-(oxan-4-yl)pyridin-2-yl]phenol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 著者 Convery, M.A, Summers, D, Peace, S. 登録日 2018-08-29 公開日 2019-09-11 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 A theoretical and experimental investigation into the conformational bias of aryl cyclopropylpyrans, novel bioisosteres for N-aryl morpholines. To be published

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