PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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6G5O	The structure of a carbohydrate active P450 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Robb, C.S, Hehemann, J.H. 登録日 2018-03-29 公開日 2018-11-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Specificity and mechanism of carbohydrate demethylation by cytochrome P450 monooxygenases. Biochem. J., 475, 2018
6G5T	Myoglobin H64V/V68A in the resting state, 1.5 Angstrom resolution 分子名称: 1,2-ETHANEDIOL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE 著者 Tinzl, M, Hayashi, T, Mori, T, Hilvert, D. 登録日 2018-03-30 公開日 2018-08-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Capture and characterization of a reactive haem-carbenoid complex in an artificial metalloenzyme Nat Catal, 1, 2018
5DDQ	L-glutamine riboswitch bound with L-glutamine soaked with Mn2+ 分子名称: GLUTAMINE, L-glutamine riboswitch RNA (61-MER), MAGNESIUM ION, ... 著者 Ren, A, Patel, D.J. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
6G5V	The X-ray structure of the adduct formed in the reaction between lysozyme and a platinum(II) terpyridine compound (pH 7.0) 分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... 著者 Merlino, A, Ferraro, G. 登録日 2018-03-30 公開日 2018-07-04 最終更新日 2018-07-11 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 A case of extensive protein platination: the reaction of lysozyme with a Pt(ii)-terpyridine complex. Dalton Trans, 47, 2018
5DF6	Crystal structure of PTPN11 tandem SH2 domains in complex with a TXNIP peptide 分子名称: Tyrosine-protein phosphatase non-receptor type 11, UNKNOWN ATOM OR ION, txnip 著者 Dong, A, Li, W, Tempel, W, Liu, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2015-08-26 公開日 2015-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP. Biochem.J., 473, 2016
3DY7	X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a complex with ligand and MgATP 分子名称: (5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ... 著者 Ohren, J.F, Pavlovsky, A, Zhang, E. 登録日 2008-07-25 公開日 2009-06-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Beyond the MEK-pocket: can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK? Bioorg.Med.Chem.Lett., 19, 2009
5DIA	PIM1 in complex with Cpd36 ((1S,3S)-N1-(6-(5-(pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridin-3-yl)pyridin-2-yl)cyclohexane-1,3-diamine) 分子名称: (1S,3S)-N-{6-[5-(pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridin-3-yl]pyridin-2-yl}cyclohexane-1,3-diamine, Serine/threonine-protein kinase pim-1 著者 Murray, J.M, Wallweber, H. 登録日 2015-08-31 公開日 2015-10-28 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.964 Å) 主引用文献 Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
8A2T	Cryo-EM structure of F-actin in the Mg2+-ADP nucleotide state. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. 登録日 2022-06-06 公開日 2022-08-10 最終更新日 2022-11-23 実験手法 ELECTRON MICROSCOPY (2.24 Å) 主引用文献 Structural basis of actin filament assembly and aging. Nature, 611, 2022
8A2Z	Cryo-EM structure of F-actin in the Ca2+-ADP nucleotide state. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. 登録日 2022-06-06 公開日 2022-08-10 最終更新日 2022-11-23 実験手法 ELECTRON MICROSCOPY (2.15 Å) 主引用文献 Structural basis of actin filament assembly and aging. Nature, 611, 2022
8A2U	Cryo-EM structure of F-actin in the Ca2+-ADP-BeF3- nucleotide state. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. 登録日 2022-06-06 公開日 2022-08-10 最終更新日 2022-11-23 実験手法 ELECTRON MICROSCOPY (2.21 Å) 主引用文献 Structural basis of actin filament assembly and aging. Nature, 611, 2022
6TVY	Structure of hen egg white lysozyme crystallized in the presence of Tb-Xo4 crystallophore in the XtalController device 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION, ... 著者 de Wijn, R, Rollet, K, Coudray, L, McEwen, A.G, Lorber, B, Sauter, C. 登録日 2020-01-10 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Monitoring the Production of High Diffraction-Quality Crystals of Two Enzymes in Real Time Using In Situ Dynamic Light Scattering Crystals, 2020
3DTQ	Engineered human lipocalin 2 with specificity for Y-DTPA, apo-form 分子名称: Neutrophil gelatinase-associated lipocalin 著者 Eichinger, A, Skerra, A. 登録日 2008-07-15 公開日 2009-05-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 High-affinity recognition of lanthanide(III) chelate complexes by a reprogrammed human lipocalin 2. J.Am.Chem.Soc., 131, 2009
8A3Q	Human Plasma Kallekrein in complex with 14W 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasma kallikrein, ... 著者 McEwan, P.A. 登録日 2022-06-08 公開日 2022-11-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema. J.Med.Chem., 65, 2022
8A2Y	Cryo-EM structure of F-actin in the Ca2+-ADP-Pi nucleotide state. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. 登録日 2022-06-06 公開日 2022-08-10 最終更新日 2022-11-23 実験手法 ELECTRON MICROSCOPY (2.15 Å) 主引用文献 Structural basis of actin filament assembly and aging. Nature, 611, 2022
5DFP	Crystal structure of PAK1 in complex with an inhibitor compound FRAX1036 分子名称: 6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, DIMETHYL SULFOXIDE, Serine/threonine-protein kinase PAK 1 著者 Maksimoska, J, Marmorstein, R, Wang, W. 登録日 2015-08-27 公開日 2016-01-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety. Acs Med.Chem.Lett., 6, 2015
3DV5	Crystal structure of human beta-secretase in complex with NVP-BAV544 分子名称: (3S,14R,16S)-16-[(1R)-1-hydroxy-2-{[3-(1-methylethyl)benzyl]amino}ethyl]-3,4,14-trimethyl-1,4-diazacyclohexadecane-2,5- dione, Beta-secretase 1 著者 Rondeau, J.-M. 登録日 2008-07-18 公開日 2009-02-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo. Bioorg.Med.Chem.Lett., 19, 2009
8A2S	Cryo-EM structure of F-actin in the Mg2+-ADP-Pi nucleotide state. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. 登録日 2022-06-06 公開日 2022-08-10 最終更新日 2022-11-23 実験手法 ELECTRON MICROSCOPY (2.22 Å) 主引用文献 Structural basis of actin filament assembly and aging. Nature, 611, 2022
6U3K	The crystal structure of 4-(pyridin-2-yl)benzoate-bound CYP199A4 分子名称: 4-(pyridin-2-yl)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bruning, J.B, Bell, S.G. 登録日 2019-08-21 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biophysical Techniques for Distinguishing Ligand Binding Modes in Cytochrome P450 Monooxygenases. Biochemistry, 59, 2020
5DGU	Crystal Structure of HIV-1 Protease Inhibitors Containing Substituted fused-Tetrahydropyranyl Tetrahydrofuran as P2-Ligand GRL-004-11A 分子名称: (3R,3aR,4S,7aS)-3-methoxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ... 著者 Agniswamy, J, Wang, Y.-F, Weber, I.T. 登録日 2015-08-28 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligands. Org.Biomol.Chem., 13, 2015
6TYH	Four-Disulfide Insulin Analog A22/B22 分子名称: ACETONE, CHLORIDE ION, GLYCEROL, ... 著者 Blakely, A.D, Xiong, X. 登録日 2019-08-08 公開日 2019-11-13 最終更新日 2020-03-11 実験手法 X-RAY DIFFRACTION (1.600019 Å) 主引用文献 Novel four-disulfide insulin analog with high aggregation stability and potency. Chem Sci, 11, 2020
5DDR	L-glutamine riboswitch bound with L-glutamine soaked with Cs+ 分子名称: CESIUM ION, GLUTAMINE, L-glutamine riboswitch RNA (61-MER), ... 著者 Ren, A, Patel, D.J. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.605 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
8A2R	Cryo-EM structure of F-actin in the Mg2+-ADP-BeF3- nucleotide state. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. 登録日 2022-06-06 公開日 2022-08-10 最終更新日 2022-11-23 実験手法 ELECTRON MICROSCOPY (2.17 Å) 主引用文献 Structural basis of actin filament assembly and aging. Nature, 611, 2022
3DY0	Crystal Structure of Cleaved PCI Bound to Heparin 分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-terminus Plasma serine protease inhibitor, GLYCEROL, ... 著者 Li, W, Huntington, J.A. 登録日 2008-07-25 公開日 2008-10-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The heparin binding site of protein C inhibitor is protease-dependent. J.Biol.Chem., 283, 2008
5DE3	The Crystal structure of Chlamydomonas reinhardtii Arl3 bound to GppNHp 分子名称: ADP-ribosylation factor-like protein 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER 著者 Gotthardt, K, Lokaj, M, Wittinghofer, A. 登録日 2015-08-25 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.417 Å) 主引用文献 The Crystal structure of Chlamydomonas reinhardtii Arl3 bound to GppNHp To Be Published
6TVL	Hen Egg White Lysozyme in complex with a "half sandwich"-type Ru(II) coordination compound 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION, ... 著者 Chiniadis, L, Giastas, P, Bratsos, I, Papakyriakou, A. 登録日 2020-01-10 公開日 2020-04-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.395 Å) 主引用文献 High-resolution crystal structures of a "half sandwich"-type Ru(II) coordination compound bound to hen egg-white lysozyme and proteinase K. J.Biol.Inorg.Chem., 25, 2020

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