PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

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5AAA	Structure of L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib 分子名称: 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, ALK TYROSINE KINASE RECEPTOR 著者 McTigue, M, Deng, Y, Liu, W, Brooun, A, Stewart, A. 登録日 2015-07-23 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Resensitization to Crizotinib by the Lorlatinib Alk Resistance Mutation L1198F. N.Engl.J.Med., 374, 2016
7XXD	Orf1-sarcosine complex 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, N-formimidoyl fortimicin A synthase, SARCOSINE 著者 Wang, Y.L, Li, T.L. 登録日 2022-05-29 公開日 2023-05-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.982 Å) 主引用文献 N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nat Commun, 14, 2023
7Y0X	Orf1-glycine complex 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCINE, N-formimidoyl fortimicin A synthase, ... 著者 Wang, Y.L, Li, T.L. 登録日 2022-06-06 公開日 2023-05-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nat Commun, 14, 2023
7XXR	Orf1 R342A-glycylthricin complex 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, N-formimidoyl fortimicin A synthase, [(2~{R},3~{R},4~{S},5~{R},6~{R})-6-[(~{E})-[(3~{a}~{S},7~{R},7~{a}~{S})-7-oxidanyl-4-oxidanylidene-3,3~{a},5,6,7,7~{a}-hexahydro-1~{H}-imidazo[4,5-c]pyridin-2-ylidene]amino]-5-(2-azanylethanoylamino)-2-(hydroxymethyl)-4-oxidanyl-oxan-3-yl] carbamate 著者 Wang, Y.L, Li, T.L. 登録日 2022-05-30 公開日 2023-05-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nat Commun, 14, 2023
4ZY1	X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10r 分子名称: CARBONATE ION, GLYCEROL, N-{(1R)-2-(hydroxyamino)-1-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-2-oxoethyl}-2,2-dimethylpropanamide, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-21 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
7XXP	F316A-glycine-streptothricin F complex 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCINE, N-formimidoyl fortimicin A synthase, ... 著者 Wang, Y.L, Li, T.L. 登録日 2022-05-30 公開日 2023-05-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.052 Å) 主引用文献 N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. Nat Commun, 14, 2023
5DPN	Engineered CBM X-2 L110F in complex with branched carbohydrate XXXG. 分子名称: CALCIUM ION, Xylanase, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-beta-D-glucopyranose 著者 Ohlin, M. 登録日 2015-09-13 公開日 2015-10-28 最終更新日 2024-05-01 実験手法 NEUTRON DIFFRACTION (1.6 Å), X-RAY DIFFRACTION 主引用文献 Neutron Crystallographic Studies Reveal Hydrogen Bond and Water-Mediated Interactions between a Carbohydrate-Binding Module and Its Bound Carbohydrate Ligand. Biochemistry, 54, 2015
5DRX	Crystal structure of the BCR Fab fragment from subset #4 case CLL240 分子名称: CLL240 BCR light chain, CLL240 heavy chain (VH and CH1 domains), GLYCEROL 著者 Minici, C, Degano, M. 登録日 2015-09-16 公開日 2016-09-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.104 Å) 主引用文献 Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia. Nat Commun, 8, 2017
3LRS	Structure of PG16, an antibody with broad and potent neutralization of HIV-1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PG-16 Heavy Chain Fab, PG-16 Light Chain Fab 著者 Pancera, M, Kwong, P.D. 登録日 2010-02-11 公開日 2010-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1. J.Virol., 84, 2010
5DRW	Crystal structure of the BCR Fab fragment from subset #4 case CLL183 分子名称: CLL183 BCR antibody heavy chain, CLL183 BCR antibody light chain 著者 Minici, C, Degano, M. 登録日 2015-09-16 公開日 2016-09-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia. Nat Commun, 8, 2017
5AYF	Crystal structure of SET7/9 in complex with cyproheptadine 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(dibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-1-methyl-piperidine, Histone-lysine N-methyltransferase SETD7, ... 著者 Niwa, H, Handa, N, Takemoto, Y, Ito, A, Tomabechi, Y, Umehara, T, Shirouzu, M, Yoshida, M, Yokoyama, S. 登録日 2015-08-20 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.005 Å) 主引用文献 Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription J.Med.Chem., 59, 2016
5B1M	The mouse nucleosome structure containing H3.1 分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B type 3-A, ... 著者 Urahama, T, Machida, S, Horikoshi, N, Osakabe, A, Tachiwana, H, Taguchi, H, Kurumizaka, H. 登録日 2015-12-08 公開日 2017-02-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis Cell Rep, 18, 2017
3KO9	DTD from Plasmodium falciparum in complex with D-Arginine 分子名称: D-ARGININE, D-tyrosyl-tRNA(Tyr) deacylase 著者 Manickam, Y, Bhatt, T.K, Sharma, A. 登録日 2009-11-13 公開日 2009-12-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
5AX9	Crystal structure of the kinase domain of human TRAF2 and NCK-interacting protein kinase in complex with compund 9 分子名称: 4-methoxy-3-[2-[(3-methoxy-4-morpholin-4-yl-phenyl)amino]pyridin-4-yl]benzenecarbonitrile, SULFATE ION, TRAF2 and NCK-interacting protein kinase 著者 Ohbayashi, N, Kukimoto-Niino, M, Yamada, T, Shirouzu, M. 登録日 2015-07-21 公開日 2016-07-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 TNIK inhibition abrogates colorectal cancer stemness Nat Commun, 7, 2016
5B1L	The mouse nucleosome structure containing H3t 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1, ... 著者 Urahama, T, Machida, S, Horikoshi, N, Osakabe, A, Tachiwana, H, Taguchi, H, Kurumizaka, H. 登録日 2015-12-08 公開日 2017-02-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis Cell Rep, 18, 2017
3KOB	DTD from Plasmodium falciparum in complex with D-Glutamic acid 分子名称: D-GLUTAMIC ACID, D-tyrosyl-tRNA(Tyr) deacylase 著者 Manickam, Y, Bhatt, T.K, Sharma, A. 登録日 2009-11-13 公開日 2009-12-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
7XAR	Crystal structure of 3C-like protease from SARS-CoV-2 in complex with covalent inhibitor 分子名称: 3C-like proteinase, 4-fluoranyl-~{N}-[(2~{S})-1-[2-(2-fluoranylethanoyl)-2-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]hydrazinyl]-4-methyl-1-oxidanylidene-pentan-2-yl]-1~{H}-indole-2-carboxamide, CHLORIDE ION, ... 著者 Caaveiro, J.M.M, Ochi, J, Takahashi, D, Ueda, T, Ojida, A. 登録日 2022-03-18 公開日 2022-11-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease. J.Med.Chem., 65, 2022
3KO4	Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, D-tyrosyl-tRNA(Tyr) deacylase 著者 Manickam, Y, Bhatt, T.K, Sharma, A. 登録日 2009-11-13 公開日 2009-12-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
3KOC	DTD from Plasmodium falciparum in complex with D-Histidine 分子名称: D-HISTIDINE, D-tyrosyl-tRNA(Tyr) deacylase 著者 Manickam, Y, Bhatt, T.K, Sharma, A. 登録日 2009-11-13 公開日 2009-12-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
3KNF	Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum 分子名称: D-tyrosyl-tRNA(Tyr) deacylase 著者 Manickam, Y, Bhatt, T.K, Sharma, A. 登録日 2009-11-12 公開日 2009-12-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
7YZV	Ryegrass mottle virus serine protease domain S159A mutant 分子名称: RNA-directed RNA polymerase 著者 Kalnins, G. 登録日 2022-02-21 公開日 2022-03-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 VPg Impact on Ryegrass Mottle Virus Serine-like 3C Protease Proteolysis and Structure. Int J Mol Sci, 24, 2023
7Z09	Crystal structure of the ground state of bacteriorhodopsin at 1.05 Angstrom resolution 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Bacteriorhodopsin, EICOSANE, ... 著者 Borshchevskiy, V, Kovalev, K, Round, E, Efremov, R, Bourenkov, G, Gordeliy, V. 登録日 2022-02-22 公開日 2022-05-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 True-atomic-resolution insights into the structure and functional role of linear chains and low-barrier hydrogen bonds in proteins. Nat.Struct.Mol.Biol., 29, 2022
7Z0A	Crystal structure of the ground state of bacteriorhodopsin at 1.22 Angstrom resolution 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Bacteriorhodopsin, EICOSANE, ... 著者 Borshchevskiy, V, Kovalev, K, Round, E, Efremov, R, Bourenkov, G, Gordeliy, V. 登録日 2022-02-22 公開日 2022-05-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 True-atomic-resolution insights into the structure and functional role of linear chains and low-barrier hydrogen bonds in proteins. Nat.Struct.Mol.Biol., 29, 2022
7Z0D	Crystal structure of the L state of bacteriorhodopsin at 1.20 Angstrom resolution 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Bacteriorhodopsin, EICOSANE, ... 著者 Borshchevskiy, V, Kovalev, K, Round, E, Efremov, R, Bourenkov, G, Gordeliy, V. 登録日 2022-02-22 公開日 2022-05-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 True-atomic-resolution insights into the structure and functional role of linear chains and low-barrier hydrogen bonds in proteins. Nat.Struct.Mol.Biol., 29, 2022
7Z0C	Crystal structure of the K state of bacteriorhodopsin at 1.53 Angstrom resolution 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Bacteriorhodopsin, EICOSANE, ... 著者 Borshchevskiy, V, Kovalev, K, Round, E, Efremov, R, Bourenkov, G, Gordeliy, V. 登録日 2022-02-22 公開日 2022-05-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 True-atomic-resolution insights into the structure and functional role of linear chains and low-barrier hydrogen bonds in proteins. Nat.Struct.Mol.Biol., 29, 2022

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