7XXR

Orf1 R342A-glycylthricin complex

Summary for 7XXR

• Entry DOI: 10.2210/pdb7xxr/pdb
• Descriptor: N-formimidoyl fortimicin A synthase, FLAVIN-ADENINE DINUCLEOTIDE, [(2~{R},3~{R},4~{S},5~{R},6~{R})-6-[(~{E})-[(3~{a}~{S},7~{R},7~{a}~{S})-7-oxidanyl-4-oxidanylidene-3,3~{a},5,6,7,7~{a}-hexahydro-1~{H}-imidazo[4,5-c]pyridin-2-ylidene]amino]-5-(2-azanylethanoylamino)-2-(hydroxymethyl)-4-oxidanyl-oxan-3-yl] carbamate, ... (4 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: Streptomyces luteocolor
• Total number of polymer chains: 8
• Total formula weight: 449470.02

Authors

Wang, Y.L.,Li, T.L. (deposition date: 2022-05-30, release date: 2023-05-31, Last modification date: 2023-11-29)

• Primary citation: Wang, Y.L.,Chang, C.Y.,Hsu, N.S.,Lo, I.W.,Lin, K.H.,Chen, C.L.,Chang, C.F.,Wang, Z.C.,Ogasawara, Y.,Dairi, T.,Maruyama, C.,Hamano, Y.,Li, T.L.; N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.; Nat Commun, 14:2528-2528, 2023; PubMed: 37137912; DOI: 10.1038/s41467-023-38218-w

Experimental method

X-RAY DIFFRACTION (2.4 Å)