6YLA
| Crystal structure of the SARS-CoV-2 receptor binding domain in complex with CR3022 Fab | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Huo, J, Zhao, Y, Ren, J, Zhou, D, Ginn, H.M, Fry, E.E, Owens, R, Stuart, D.I. | 登録日 | 2020-04-06 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike. Cell Host Microbe, 28, 2020
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6Z06
| Crystal structure of Puumala virus Gc in complex with Fab 4G2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, Fab 4G2 Heavy chain, ... | 著者 | Rissanen, I.R, Stass, R, Krumm, S.A, Seow, J, Hulswit, R.J.G, Paesen, G.C, Hepojoki, J, Vapalahti, O, Lundkvist, A, Reynard, O, Volchkov, V, Doores, K.J, Huiskonen, J.T, Bowden, T.A. | 登録日 | 2020-05-07 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein. Elife, 9, 2020
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7ABG
| Human pre-Bact-1 spliceosome | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | 登録日 | 2020-09-07 | 公開日 | 2020-12-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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7ABI
| Human pre-Bact-2 spliceosome | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ... | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | 登録日 | 2020-09-07 | 公開日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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7ABH
| Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | 分子名称: | Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ... | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | 登録日 | 2020-09-07 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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7AAQ
| sugar/H+ symporter STP10 in outward occluded conformation | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, ACETATE ION, ... | 著者 | Bavnhoej, L, Paulsen, P.A, Pedersen, B.P. | 登録日 | 2020-09-04 | 公開日 | 2021-08-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Molecular mechanism of sugar transport in plants unveiled by structures of glucose/H + symporter STP10. Nat.Plants, 7, 2021
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7AAR
| sugar/H+ symporter STP10 in inward open conformation | 分子名称: | CHLORIDE ION, Octyl Glucose Neopentyl Glycol, Sugar transport protein 10, ... | 著者 | Bavnhoej, L, Paulsen, P.A, Pedersen, B.P. | 登録日 | 2020-09-04 | 公開日 | 2021-08-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Molecular mechanism of sugar transport in plants unveiled by structures of glucose/H + symporter STP10. Nat.Plants, 7, 2021
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7AFV
| Crystal structure of tetrameric beta-2-microglobulin deltaN6 S52C stabilized by a covalent ligand | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-oxidanylidene-~{N}-(2-sulfanylethyl)-2,3-dihydro-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide, Beta-2-microglobulin | 著者 | Guthertz, N, Cawood, E, Karamanos, T. | 登録日 | 2020-09-20 | 公開日 | 2020-12-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules. J.Am.Chem.Soc., 142, 2020
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7B09
| Puumala virus glycoprotein (Gc) in complex with fab fragment P-4G2. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, ... | 著者 | Rissanen, I, Stass, R, Huiskonen, J.T, Bowden, T.A. | 登録日 | 2020-11-19 | 公開日 | 2020-12-16 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (13.4 Å) | 主引用文献 | Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein. Elife, 9, 2020
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7B0Y
| Structure of a transcribing RNA polymerase II-U1 snRNP complex | 分子名称: | 145-nt RNA, DNA-directed RNA polymerase II subunit D, DNA-directed RNA polymerase II subunit E, ... | 著者 | Zhang, S, Aibara, S, Vos, S.M, Agafonov, D.E, Luehrmann, R, Cramer, P. | 登録日 | 2020-11-23 | 公開日 | 2021-01-13 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of a transcribing RNA polymerase II-U1 snRNP complex. Science, 371, 2021
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5IFJ
| Crystal structure of anti-gliadin 1002-1E01 Fab fragment in complex of peptide PLQPEQPFP | 分子名称: | 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, SULFATE ION, ... | 著者 | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | 登録日 | 2016-02-26 | 公開日 | 2017-03-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease. JCI Insight, 2, 2017
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6NMV
| Non-Blocking Fab 218 anti-SIRP-alpha antibody in complex with SIRP-alpha Variant 1 | 分子名称: | Fab 218 anti-SIRP-alpha antibody Variable Heavy Chain, Fab 218 anti-SIRP-alpha antibody Variable Light Chain, Tyrosine-protein phosphatase non-receptor type substrate 1 | 著者 | Wibowo, A.S, Carter, J.J, Sim, J. | 登録日 | 2019-01-11 | 公開日 | 2019-08-07 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRP alpha. Mabs, 11, 2019
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6NN3
| Structure of parvovirus B19 decorated with Fab molecules from a human antibody | 分子名称: | Fab monoclonal antibody 860-55D, heavy chain, light chain, ... | 著者 | Rossmann, M.G, Sun, Y, Klose, T, Liu, Y. | 登録日 | 2019-01-14 | 公開日 | 2019-02-13 | 最終更新日 | 2020-03-04 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Structure of Parvovirus B19 Decorated by Fabs from a Human Antibody. J. Virol., 93, 2019
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6NMR
| Blocking Fab 119 anti-SIRP-alpha antibody in complex with SIRP-alpha Variant 1 | 分子名称: | Fab 119 anti-SIRP-alpha antibody Variable Heavy Chain, Fab 119 anti-SIRP-alpha antibody Variable Light Chain, Tyrosine-protein phosphatase non-receptor type substrate 1 | 著者 | Wibowo, A.S, Carter, J.J, Sim, J. | 登録日 | 2019-01-11 | 公開日 | 2019-08-07 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRP alpha. Mabs, 11, 2019
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7MXE
| Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ... | 著者 | Abernathy, M.E, Bjorkman, P.J. | 登録日 | 2021-05-19 | 公開日 | 2021-10-27 | 最終更新日 | 2021-11-03 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope. Npj Vaccines, 6, 2021
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7M7H
| 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1' | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | 登録日 | 2021-03-28 | 公開日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7F
| 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1 | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | 登録日 | 2021-03-28 | 公開日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7I
| 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2 (TE-free) | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), EryAI, ... | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | 登録日 | 2021-03-28 | 公開日 | 2021-11-17 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7G
| 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 2 | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | 登録日 | 2021-03-28 | 公開日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7E
| 6-Deoxyerythronolide B synthase (DEBS) hybrid module (M3/1) in complex with antibody fragment 1B2 | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), 6-deoxyerythronolide-B synthase EryA2, ... | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | 登録日 | 2021-03-28 | 公開日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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7M7J
| 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: "turnstile closed" state (TE-free) | 分子名称: | 1B2 (heavy chain), 1B2 (light chain), EryAI | 著者 | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | 登録日 | 2021-03-28 | 公開日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
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6NMT
| Non-Blocking Fab 3 anti-SIRP-alpha antibody in complex with SIRP-alpha Variant 1 | 分子名称: | Fab 3 anti-SIRP-alpha antibody Variable Heavy Chain, Fab 3 anti-SIRP-alpha antibody Variable Light Chain, Tyrosine-protein phosphatase non-receptor type substrate 1 | 著者 | Wibowo, A.S, Carter, J.J, Sim, J. | 登録日 | 2019-01-11 | 公開日 | 2019-08-07 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRP alpha. Mabs, 11, 2019
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7MW6
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7MW4
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7MW5
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