PDB: 522 件ウェブページステータス検索Chemie searchBIRD

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7UD6	Designed Enzyme SH3-588 (Catechol O-methyltransferase catalytic domain and Src homology 3 binding domain fusion) 分子名称: POTASSIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Tyrosine-protein kinase Fyn,Catechol O-methyltransferase 著者 Ongpipattanakul, C, Nair, S.K. 登録日 2022-03-18 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Designer installation of a substrate recruitment domain to tailor enzyme specificity. Nat.Chem.Biol., 19, 2023
7CSP	Structure of Ephexin4 IDPSH 分子名称: Rho guanine nucleotide exchange factor 16 著者 Zhang, M, Lin, L, Wang, C, Zhu, J. 登録日 2020-08-15 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Double inhibition and activation mechanisms of Ephexin family RhoGEFs. Proc.Natl.Acad.Sci.USA, 118, 2021
7CSR	Structure of Ephexin4 R676L 分子名称: Rho guanine nucleotide exchange factor 16 著者 Zhang, M, Lin, L, Wang, C, Zhu, J. 登録日 2020-08-17 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Double inhibition and activation mechanisms of Ephexin family RhoGEFs. Proc.Natl.Acad.Sci.USA, 118, 2021
7CSO	Structure of Ephexin4 DH-PH-SH3 分子名称: Rho guanine nucleotide exchange factor 16, SULFATE ION 著者 Zhang, M, Lin, L, Wang, C, Zhu, J. 登録日 2020-08-15 公開日 2021-02-24 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Double inhibition and activation mechanisms of Ephexin family RhoGEFs. Proc.Natl.Acad.Sci.USA, 118, 2021
7D7S	HIV-1 SF2 Nef in complex with the Fyn SH3 R96I mutant 分子名称: Protein Nef, Tyrosine-protein kinase Fyn 著者 Aldehaiman, A, Shahul Hamed, U.F, Arold, S.T. 登録日 2020-10-05 公開日 2020-11-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.32 Å) 主引用文献 Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478, 2021
7DPA	Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex 分子名称: Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 著者 Kukimoto-Niino, M, Katsura, K, Kaushik, R, Ehara, H, Yokoyama, T, Uchikubo-Kamo, T, Mishima-Tsumagari, C, Yonemochi, M, Ikeda, M, Hanada, K, Zhang, K.Y.J, Shirouzu, M. 登録日 2020-12-18 公開日 2021-08-04 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex. Sci Adv, 7, 2021
8F2P	Nef SF2 dimerization mutant bound to Hck SH3 分子名称: C-terminal core protein, Tyrosine-protein kinase HCK 著者 Thomas, C.E, Alvarado, J.J, Smithgall, T.E. 登録日 2022-11-08 公開日 2023-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Neutron Reflectometry and Molecular Simulations Demonstrate HIV-1 Nef Homodimer Formation on Model Lipid Bilayers. J.Mol.Biol., 435, 2023
6UY7	Crystal structure of the STAC3 tandem SH3 domains - P269R 分子名称: 1,2-ETHANEDIOL, SH3 and cysteine-rich domain-containing protein 3 著者 Rufenach, B, Van Petegem, F. 登録日 2019-11-12 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.105 Å) 主引用文献 Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling. Structure, 28, 2020
6UY9	Crystal structure of the STAC3 tandem SH3 domains - P269R, W284S 分子名称: 1,2-ETHANEDIOL, SH3 and cysteine-rich domain-containing protein 3, SODIUM ION 著者 Rufenach, B, Van Petegem, F. 登録日 2019-11-12 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling. Structure, 28, 2020
6UY8	Crystal structure of the STAC3 tandem SH3 domains - P269R, K329N 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SH3 and cysteine-rich domain-containing protein 3 著者 Rufenach, B, Van Petegem, F. 登録日 2019-11-12 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.649 Å) 主引用文献 Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling. Structure, 28, 2020
6B25	Crystal structure of human STAC1 Tandem SH3 Domains (288-402) 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SH3 and cysteine-rich domain-containing protein 著者 Wong King Yuen, S.M, Van Petegem, F. 登録日 2017-09-19 公開日 2017-10-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4D8D	Crystal structure of HIV-1 NEF Fyn-SH3 R96W variant 分子名称: GLYCEROL, Protein Nef, Tyrosine-protein kinase Fyn 著者 Arold, S.T, Hoh, F, Dumas, C. 登録日 2012-01-10 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5201 Å) 主引用文献 Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478, 2021
3NMZ	Crystal structure of APC complexed with Asef 分子名称: APC variant protein, Rho guanine nucleotide exchange factor 4 著者 Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. 登録日 2010-06-23 公開日 2011-07-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Res., 22, 2012
3JV3	Structure of SH3E-DH unit of murine intersectin-1L 分子名称: Intersectin-1 著者 Ahmad, K.F. 登録日 2009-09-15 公開日 2010-07-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The minimal autoinhibited unit of the guanine nucleotide exchange factor intersectin. Plos One, 5, 2010
7SJ4	Human Trio residues 1284-1959 in complex with Rac1 分子名称: Ras-related C3 botulinum toxin substrate 1, Triple functional domain protein 著者 Chen, C.-L, Ravala, S.K, Bandekar, S.J, Cash, J, Tesmer, J.J.G. 登録日 2021-10-15 公開日 2022-07-06 最終更新日 2022-08-24 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1. J.Biol.Chem., 298, 2022
3REB	HIV-1 Nef protein in complex with engineered Hck-SH3 domain 分子名称: Protein Nef, Tyrosine-protein kinase HCK 著者 Schulte, A, Blankenfeldt, W, Geyer, M. 登録日 2011-04-04 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef. PLoS ONE, 6, 2011
3RBB	HIV-1 NEF protein in complex with engineered HCK SH3 domain 分子名称: 1,2-ETHANEDIOL, Protein Nef, Tyrosine-protein kinase HCK 著者 Horenkamp, F.A, Schulte, A, Weyand, M, Geyer, M. 登録日 2011-03-29 公開日 2011-04-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly. Traffic, 12, 2011
3REA	HIV-1 Nef protein in complex with engineered Hck-SH3 domain 分子名称: Protein Nef, Tyrosine-protein kinase HCK 著者 Schulte, A, Blankenfeldt, W, Geyer, M. 登録日 2011-04-04 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef. PLoS ONE, 6, 2011
2XKX	Single particle analysis of PSD-95 in negative stain 分子名称: DISKS LARGE HOMOLOG 4 著者 Fomina, S, Howard, T.D, Sleator, O.K, Golovanova, M, O'Ryan, L, Leyland, M.L, Grossmann, J.G, Collins, R.F, Prince, S.M. 登録日 2010-07-15 公開日 2011-07-20 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (22.9 Å), SOLUTION SCATTERING 主引用文献 Self-Directed Assembly and Clustering of the Cytoplasmic Domains of Inwardly Rectifying Kir2.1 Potassium Channels on Association with Psd-95 Biochim.Biophys.Acta, 1808, 2011
4N78	The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton 分子名称: Abl interactor 2, CHLORIDE ION, Cytoplasmic FMR1-interacting protein 1, ... 著者 Chen, Z.C. 登録日 2013-10-15 公開日 2014-02-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton. Cell(Cambridge,Mass.), 156, 2014
4ORZ	HIV-1 Nef protein in complex with single domain antibody sdAb19 and an engineered Hck SH3 domain 分子名称: Protein Nef, Tyrosine-protein kinase HCK, single domain antibody sdAb19 著者 Geyer, M, Lulf, S. 登録日 2014-02-12 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the inhibition of HIV-1 Nef by a high-affinity binding single-domain antibody. Retrovirology, 11, 2014
5NUH	Crystal structure of SIVmac239 Nef bound to an engineered Hck SH3 domain 分子名称: Protein Nef, Tyrosine-protein kinase HCK,Tyrosine-protein kinase HCK 著者 Horenkamp, F.A, Anand, K, Geyer, M. 登録日 2017-04-30 公開日 2017-08-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3. Nat Commun, 8, 2017
3EHQ	Crystal Structure of Human Osteoclast Stimulating Factor 分子名称: 1,2-ETHANEDIOL, Osteoclast-stimulating factor 1 著者 Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. 登録日 2008-09-14 公開日 2009-08-04 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Crystal structure of human osteoclast stimulating factor Proteins, 75, 2009
3EHR	Crystal Structure of Human Osteoclast Stimulating Factor 分子名称: Osteoclast-stimulating factor 1 著者 Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. 登録日 2008-09-14 公開日 2009-08-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of human osteoclast stimulating factor Proteins, 75, 2009
3UAT	Guanylate Kinase Domains of the MAGUK Family Scaffold Proteins as Specific Phospho-Protein Binding Modules 分子名称: Disks large homolog 1, phosphor-LGN peptide 著者 Shang, Y, Zhu, J, Wen, W, Zhang, M. 登録日 2011-10-22 公開日 2011-12-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules Embo J., 2011

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