8ZJM

Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 5)

Summary for 8ZJM

Entry DOI	10.2210/pdb8zjm/pdb
Related	8JHK 8XM7 8ZJ2 8ZJI 8ZJJ 8ZJK 8ZJL
EMDB information	60146 60147 60148 60149 60150
Descriptor	Engulfment and cell motility protein 1, Dedicator of cytokinesis protein 5, Ras-related C3 botulinum toxin substrate 1 (3 entities in total)
Functional Keywords	elmo, dock, gef, gtpase, rho, rac, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	592148.20
Authors	Kukimoto-Niino, M.,Katsura, K.,Ishizuka-Katsura, Y.,Mishima-Tsumagari, C.,Yonemochi, M.,Inoue, M.,Nakagawa, R.,Kaushik, R.,Zhang, K.Y.J.,Shirouzu, M. (deposition date: 2024-05-15, release date: 2024-06-26, Last modification date: 2024-07-17)
Primary citation	Kukimoto-Niino, M.,Katsura, K.,Ishizuka-Katsura, Y.,Mishima-Tsumagari, C.,Yonemochi, M.,Inoue, M.,Nakagawa, R.,Kaushik, R.,Zhang, K.Y.J.,Shirouzu, M. RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300:107459-107459, 2024 Cited by PubMed: 38857861 DOI: 10.1016/j.jbc.2024.107459 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.52 Å)

Structure validation