PDB: 594 件ウェブページステータス検索Chemie searchBIRD

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2L3T	Solution structure of tandem SH2 domain from Spt6 分子名称: Transcription elongation factor SPT6 著者 Liu, J, Zhang, J, Wu, J, Shi, Y. 登録日 2010-09-22 公開日 2011-06-15 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of the tandem SH2 domains from Spt6 and their binding to the phosphorylated RNA polymerase II C-terminal domain To be Published
2KNO	NMR Solution Structure of SH2 Domain of the Human Tensin Like C1 Domain Containing Phosphatase (TENC1) 分子名称: Tensin-like C1 domain-containing phosphatase 著者 Chen, L, Feng, R, Liu, C, Zhu, G. 登録日 2009-08-27 公開日 2010-09-01 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 NMR Solution Structure of SH2 Domain of the Human Tensin Like C1 Domain Containing Phosphatase (TENC1) To be Published
2KK6	Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d 分子名称: Proto-oncogene tyrosine-protein kinase FER 著者 Tang, Y, Wang, D, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2009-06-15 公開日 2009-08-11 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d To be Published
2K7A	Ensemble Structures of the binary complex between the SH3 and SH2 domain of interleukin-2 tyrosine kinase. 分子名称: SH2 domain of Tyrosine-protein kinase ITK/TSK, SH3 domain of Tyrosine-protein kinase ITK/TSK 著者 Andreotti, A.H, Severin, A.J, Fulton, D.B. 登録日 2008-08-08 公開日 2009-03-10 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain. J.Mol.Biol., 387, 2009
2K79	Solution Structure of the binary complex between the SH3 and SH2 domain of interleukin-2 tyrosine kinase 分子名称: SH2 domain of Tyrosine-protein kinase ITK/TSK, SH3 domain of Tyrosine-protein kinase ITK/TSK 著者 Andreotti, A.H, Severin, A.J, Fulton, D.B. 登録日 2008-08-08 公開日 2009-03-10 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain. J.Mol.Biol., 387, 2009
2JYQ	NMR structure of the apo v-Src SH2 domain 分子名称: Tyrosine-protein kinase transforming protein Src 著者 Taylor, J.D, Ababou, A, Williams, M.A, Ladbury, J.E. 登録日 2007-12-17 公開日 2008-06-24 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure, dynamics, and binding thermodynamics of the v-Src SH2 domain: Implications for drug design Proteins, 73, 2008
2IZV	CRYSTAL STRUCTURE OF SOCS-4 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 2.55A RESOLUTION 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... 著者 Debreczeni, J.E, Bullock, A, Papagrigoriou, E, Turnbull, A, Pike, A.C.W, Gorrec, F, von Delft, F, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Knapp, S. 登録日 2006-07-26 公開日 2006-08-02 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation. Structure, 15, 2007
2IUI	Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with PDGFR phosphotyrosyl peptide 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Platelet-derived growth factor receptor beta 著者 Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. 登録日 2006-06-03 公開日 2006-06-06 最終更新日 2021-04-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Pi 3-Kinase P85 Amino- Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
2IUH	Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with c-Kit phosphotyrosyl peptide 分子名称: C-KIT PHOSPHOTYROSYL PEPTIDE, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT 著者 Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. 登録日 2006-06-03 公開日 2006-06-06 最終更新日 2021-04-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
2IUG	Crystal structure of the PI3-kinase p85 N-terminal SH2 domain 分子名称: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT 著者 Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. 登録日 2006-06-03 公開日 2006-06-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
2HUW	X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand 分子名称: Growth factor receptor-bound protein 2, N-({(1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropyl}carbonyl)-L-valyl-L-aspartamide, PHOSPHATE ION 著者 Benfield, A.P, Martin, S.F. 登録日 2006-07-27 公開日 2006-08-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ligand Preorganization May Be Accompanied by Entropic Penalties in Protein-Ligand Interactions. Angew.Chem.Int.Ed.Engl., 45, 2006
2HMH	Crystal structure of SOCS3 in complex with gp130(pTyr757) phosphopeptide. 分子名称: Interleukin-6 receptor beta chain, Suppressor of cytokine signaling 3 著者 Bergamin, E, Wu, J, Hubbard, S.R. 登録日 2006-07-11 公開日 2006-08-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3. Structure, 14, 2006
2HDX	Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide 分子名称: Jak2 protein, SH2-B PH domain containing signaling mediator 1 gamma isoform 著者 Hu, J, Hubbard, S.R. 登録日 2006-06-21 公開日 2006-08-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS. J.Mol.Biol., 361, 2006
2HDV	Crystal structure of the Src Homology-2 domain of the adapter protein SH2-B 分子名称: SH2-B PH domain containing signaling mediator 1 gamma isoform 著者 Hu, J, Hubbard, S.R. 登録日 2006-06-20 公開日 2006-08-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS. J.Mol.Biol., 361, 2006
2HCK	SRC FAMILY KINASE HCK-QUERCETIN COMPLEX 分子名称: 3,5,7,3',4'-PENTAHYDROXYFLAVONE, CALCIUM ION, HEMATOPOETIC CELL KINASE HCK 著者 Sicheri, F, Moarefi, I, Kuriyan, J. 登録日 1997-02-25 公開日 1997-08-20 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the Src family tyrosine kinase Hck. Nature, 385, 1997
2H8H	Src kinase in complex with a quinazoline inhibitor 分子名称: N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE, Proto-oncogene tyrosine-protein kinase Src 著者 Otterbein, L.R, Norman, R, Pauptit, R.A, Rowsell, S, Breed, J. 登録日 2006-06-07 公開日 2006-11-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor. J.Med.Chem., 49, 2006
2H5K	Crystal Structure of Complex Between the Domain-Swapped Dimeric Grb2 SH2 Domain and Shc-Derived Ligand, Ac-NH-pTyr-Val-Asn-NH2 分子名称: CACODYLATE ION, Growth factor receptor-bound protein 2, Shc-Derived Ligand 著者 Benfield, A.P, Whiddon, B.B, Martin, S.F. 登録日 2006-05-26 公開日 2006-08-15 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structural and energetic aspects of Grb2-SH2 domain-swapping. Arch.Biochem.Biophys., 462, 2007
2H46	Native domain-swapped dimer crystal structure of the Grb2 SH2 domain 分子名称: GLYCEROL, Growth Receptor Binding Protein 2 著者 Benfield, A.P, Martin, S.F, Whiddon, B.B. 登録日 2006-05-23 公開日 2006-06-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and energetic aspects of Grb2-SH2 domain-swapping. Arch.Biochem.Biophys., 462, 2007
2GSB	Solution structure of the second SH2 domain of human Ras GTPase-activating protein 1 分子名称: Ras GTPase-activating protein 1 著者 Kurosaki, C, Suetake, T, Yoshida, M, Hayashi, F, Yokoyma, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-26 公開日 2007-05-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the second SH2 domain of human Ras GTPase-activating protein 1 To be Published
2GE9	Solution Structures of the SH2 domain of Bruton's Tyrosine Kinase 分子名称: Tyrosine-protein kinase BTK 著者 Cheng, J.-W, Huang, K.-C. 登録日 2006-03-18 公開日 2006-10-24 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase J.Biomol.Nmr, 36, 2006
2FO0	Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase 分子名称: 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... 著者 Nagar, B, Hantschel, O, Seeliger, M, Davies, J.M, Weis, W.I, Superti-Furga, G, Kuriyan, J. 登録日 2006-01-12 公開日 2006-03-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase. Mol.Cell, 21, 2006
2FCI	Structural basis for the requirement of two phosphotyrosines in signaling mediated by Syk tyrosine kinase 分子名称: C-termainl SH2 domain from phospholipase C-gamma-1 comprising residues 663-759, Doubly phosphorylated peptide derived from Syk kinase comprising residues 338-350 著者 Groesch, T.D, Zhou, F, Mattila, S, Geahlen, R.L, Post, C.B. 登録日 2005-12-12 公開日 2006-01-31 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by syk tyrosine kinase J.Mol.Biol., 356, 2006
2EYZ	CT10-Regulated Kinase isoform II 分子名称: v-crk sarcoma virus CT10 oncogene homolog isoform a 著者 Kobashigawa, Y, Tanaka, S, Inagaki, F. 登録日 2005-11-10 公開日 2006-11-10 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007
2EYY	CT10-Regulated Kinase isoform I 分子名称: v-crk sarcoma virus CT10 oncogene homolog isoform a 著者 Kobashigawa, Y, Tanaka, S, Inagaki, F. 登録日 2005-11-10 公開日 2006-11-10 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007
2EYV	SH2 domain of CT10-Regulated Kinase 分子名称: v-crk sarcoma virus CT10 oncogene homolog isoform a 著者 Kobashigawa, Y, Tanaka, S, Inagaki, F. 登録日 2005-11-10 公開日 2006-11-10 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007

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