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2NC1
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BU of 2nc1 by Molmil
Solution structure of the delta-J-delta-K domain of EMCV IRES
分子名称: IRES RNA (67-MER)
著者Imai, S, D'Souza, V, Wagner, G.
登録日2016-03-16
公開日2016-08-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献An accurately preorganized IRES RNA structure enables eIF4G capture for initiation of viral translation.
Nat. Struct. Mol. Biol., 23, 2016
7QCL
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BU of 7qcl by Molmil
Structure of the MUCIN-2 Cterminal domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-2, ...
著者Gallego, P, Hansson, G.C.
登録日2021-11-24
公開日2023-03-08
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins.
Nat Commun, 14, 2023
5LWB
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BU of 5lwb by Molmil
Crystal structure of human JARID1B in complex with S40650a
分子名称: 1,2-ETHANEDIOL, 5-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-7-oxidanylidene-6-propan-2-yl-6~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile, DIMETHYL SULFOXIDE, ...
著者Srikannathasan, V, Le Bihan, Y.V, Szykowska, A, Johansson, C, Gileadi, C, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Oppermann, U, Huber, K.
登録日2016-09-15
公開日2016-10-26
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal structure of human JARID1B in complex with S40650a
to be published
7E30
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BU of 7e30 by Molmil
Crystal structure of a novel alpha/beta hydrolase in apo form in complex with citrate
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CITRIC ACID, SULFATE ION, ...
著者Gao, J, Han, X, Zheng, Y.Y, Liu, W.D.
登録日2021-02-07
公開日2022-02-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
7E31
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BU of 7e31 by Molmil
Crystal structure of a novel alpha/beta hydrolase mutant in apo form
分子名称: TRIETHYLENE GLYCOL, alpha/beta hydrolase
著者Gao, J, Han, X, Zheng, Y.Y, Liu, W.D.
登録日2021-02-07
公開日2022-02-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase.
Acs Catalysis, 12, 2022
3SLA
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BU of 3sla by Molmil
X-ray structure of first four repeats of human beta-catenin
分子名称: Catenin beta-1, GLYCEROL, SODIUM ION
著者Gupta, D, Bienz, M.
登録日2011-06-24
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
3SL9
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BU of 3sl9 by Molmil
X-ray structure of Beta catenin in complex with Bcl9
分子名称: 1,2-ETHANEDIOL, B-cell CLL/lymphoma 9 protein, Catenin beta-1, ...
著者Gupta, D, Bienz, M.
登録日2011-06-24
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
6EKC
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BU of 6ekc by Molmil
Crystal structure of the BSD2 homolog of Arabidopsis thaliana bound to the octameric assembly of RbcL from Thermosynechococcus elongatus
分子名称: DnaJ/Hsp40 cysteine-rich domain superfamily protein, Ribulose bisphosphate carboxylase large chain, ZINC ION
著者Aigner, H, Wilson, R.H, Bracher, A, Calisse, L, Bhat, J.Y, Hartl, F.U, Hayer-Hartl, M.
登録日2017-09-26
公開日2017-12-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Plant RuBisCo assembly in E. coli with five chloroplast chaperones including BSD2.
Science, 358, 2017
3QHZ
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BU of 3qhz by Molmil
Crystal Structure of human anti-influenza Fab 2D1
分子名称: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
著者Ekiert, D.C, Wilson, I.A.
登録日2011-01-26
公開日2011-02-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
3QHF
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BU of 3qhf by Molmil
Crystal Structure of Fab del2D1, a deletion variant of anti-influenza antibody 2D1
分子名称: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
著者Ekiert, D.C, Wilson, I.A.
登録日2011-01-25
公開日2011-02-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.655 Å)
主引用文献An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
8EK6
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BU of 8ek6 by Molmil
UCA Y35N (unbound) Fab from CH65-CH67 lineage
分子名称: UCA Fab heavy chain, UCA Fab light chain
著者Maurer, D.P, Schmidt, A.G.
登録日2022-09-20
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.954 Å)
主引用文献Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody.
Elife, 12, 2023
8EKH
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BU of 8ekh by Molmil
I-2 Y35N H35N (unbound) Fab from CH65-CH67 lineage
分子名称: I-2 Fab heavy chain, I-2 Fab light chain
著者Maurer, D.P, Schmidt, A.G.
登録日2022-09-21
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody.
Elife, 12, 2023
8F38
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BU of 8f38 by Molmil
Cryo-EM structure of X6 COBRA (H1N1) hemagglutinin bound to CR6261 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-11-09
公開日2023-12-13
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6.
Structure, 2024
4PY5
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BU of 4py5 by Molmil
Thermovibrio ammonificans RNase H3 in complex with 19-mer RNA/DNA
分子名称: 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*C)-3', 5'-R(*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', GLYCEROL, ...
著者Figiel, M, Nowotny, M.
登録日2014-03-26
公開日2014-07-30
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of RNase H3-substrate complex reveals parallel evolution of RNA/DNA hybrid recognition.
Nucleic Acids Res., 42, 2014
8FQC
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BU of 8fqc by Molmil
Structure of baseplate with receptor binding complex of Agrobacterium phage Milano
分子名称: Baseplate Centerpiece, gp25, Baseplate Central Spike, ...
著者Sonani, R.R, Leiman, P.G, Wang, F, Kreutzberger, M.A.B, Sebastian, A, Esteves, N.C, Kelly, R.J, Scharf, B, Egelman, E.H.
登録日2023-01-05
公開日2024-01-31
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献An extensive disulfide bond network prevents tail contraction in Agrobacterium tumefaciens phage Milano.
Nat Commun, 15, 2024
5FUU
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BU of 5fuu by Molmil
Ectodomain of cleaved wild type JR-FL EnvdCT trimer in complex with PGT151 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lee, J.H, Ward, A.B.
登録日2016-01-29
公開日2016-03-09
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-Em Structure of a Native, Fully Glycosylated and Cleaved HIV-1 Envelope Trimer
Science, 351, 2016
6UR5
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BU of 6ur5 by Molmil
Resurfaced influenza hemagglutinin in complex with a broadly neutralizing antibody
分子名称: Antibody heavy chain, Antibody light chain, GLYCEROL, ...
著者Bajic, G, Schmidt, A.G.
登録日2019-10-22
公開日2020-06-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure-Guided Molecular Grafting of a Complex Broadly Neutralizing Viral Epitope.
Acs Infect Dis., 6, 2020
6OLP
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BU of 6olp by Molmil
Full length HIV-1 Env AMC011 in complex with PGT151 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rantalainen, K, Cottrell, C.A.
登録日2019-04-16
公開日2019-07-31
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics.
Plos Pathog., 15, 2019
6WCR
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BU of 6wcr by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule F0045(S)
分子名称: (2,4-dichlorophenyl)[(2S)-2-phenylmorpholin-4-yl]methanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者kadam, R.U, Wilson, I.A.
登録日2020-03-31
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
Proc.Natl.Acad.Sci.USA, 117, 2020
1UOR
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BU of 1uor by Molmil
X-RAY STUDY OF RECOMBINANT HUMAN SERUM ALBUMIN. PHASES DETERMINED BY MOLECULAR REPLACEMENT METHOD, USING LOW RESOLUTION STRUCTURE MODEL OF TETRAGONAL FORM OF HUMAN SERUM ALBUMIN
分子名称: SERUM ALBUMIN
著者Carter, D.C, Ho, J.X.
登録日1998-03-10
公開日1998-05-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Atomic structure and chemistry of human serum albumin.
Nature, 358, 1992
2RF6
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BU of 2rf6 by Molmil
Crystal Structure of the Vaccinia Virus Dual-Specificity Phosphatase VH1
分子名称: Dual specificity protein phosphatase, SULFATE ION
著者Koksal, A.C, Cingolani, G.
登録日2007-09-28
公開日2008-09-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of the Vaccinia Virus Dual-Specificity Phosphatase VH1
To be Published
2B8H
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BU of 2b8h by Molmil
A/NWS/whale/Maine/1/84 (H1N9) reassortant influenza virus neuraminidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Smith, B.J, Platis, D, Cox, M.M.J, Huyton, T, Joosten, R.P, McKimm-Breschkin, J.L, Zhang, J.-G, Luo, C.S, Lou, M.-Z, Garrett, T.P.J, Labrou, N.E.
登録日2005-10-07
公開日2006-09-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a calcium-deficient form of influenza virus neuraminidase: implications for substrate binding.
Acta Crystallogr.,Sect.D, 62, 2006
6BF4
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BU of 6bf4 by Molmil
Crystal Structure of HIV-1 Clade AE Strain CNE55 gp120 Core in Complex with Neutralizing Antibody VRC-PG05 that Targets the Center of the Silent Face on the Outer Domain of gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhou, T, Kwong, P.D.
登録日2017-10-25
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.382 Å)
主引用文献A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.
Immunity, 48, 2018
6B0N
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BU of 6b0n by Molmil
Crystal structure of the cleavage-independent prefusion HIV Env glycoprotein trimer of the clade A BG505 isolate (NFL construct) in complex with Fabs PGT122 and PGV19 at 3.39 A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp140, ...
著者Sarkar, A, Irimia, A, Wilson, I.A.
登録日2017-09-14
公開日2018-05-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
Nat Commun, 9, 2018
6CH7
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BU of 6ch7 by Molmil
XFEL crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2018-02-22
公開日2018-05-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018

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