PDB: 5470 件ウェブページステータス検索Chemie searchBIRD

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7EIC	Crystal structure of AF9 YEATS domain in complex with H4K5acK8ac peptide 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Histone H4, ... 著者 Kikuchi, M, Umehara, T. 登録日 2021-03-30 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Elucidation of binding preferences of YEATS domains to site-specific acetylated nucleosome core particles. J.Biol.Chem., 298, 2022
7EID	Crystal structure of AF9 YEATS domain in complex with H4K8acK12ac peptide 分子名称: GLYCEROL, Histone H4, Protein AF-9 著者 Kikuchi, M, Umehara, T. 登録日 2021-03-30 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Elucidation of binding preferences of YEATS domains to site-specific acetylated nucleosome core particles. J.Biol.Chem., 298, 2022
7EIK	RD4-BD1 in complex with LT-872-297 分子名称: 1-[2-methyl-5-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-4-(1-methylpyrazol-4-yl)-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4 著者 Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y. 登録日 2021-03-31 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 RD4-BD1 in complex with LT-872-297 To Be Published
7EIL	BRD4-BD1 in complex with LT-909-110 分子名称: Bromodomain-containing protein 4, N-[4-[4-ethanoyl-5-methyl-2-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-pyrrol-3-yl]phenyl]ethanamide 著者 Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y. 登録日 2021-03-31 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of 1-(5-(1H-benzo[d]imidazole-2-yl)-2,4-dimethyl-1H-pyrrol-3-yl)ethan-1-one derivatives as novel and potent bromodomain and extra-terminal (BET) inhibitors with anticancer efficacy Eur.J.Med.Chem., 227, 2022
2OWB	Structure of the Catalytic Domain of Human Polo-like Kinase 1 分子名称: 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE, ACETATE ION, Serine/threonine-protein kinase PLK1, ... 著者 Ding, Y.-H, Kothe, M, Kohls, D, Low, S. 登録日 2007-02-15 公開日 2007-04-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the catalytic domain of human polo-like kinase 1. Biochemistry, 46, 2007
7EIF	Crystal structure of GAS41 YEATS domain 分子名称: GLYCEROL, YEATS domain-containing protein 4 著者 Kikuchi, M, Umehara, T. 登録日 2021-03-30 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proc.Natl.Acad.Sci.USA, 120, 2023
2N0T	Structural ensemble of the enzyme cyclophilin reveals an orchestrated mode of action at atomic resolution 分子名称: Peptidyl-prolyl cis-trans isomerase A 著者 Chi, C.N, Voegeli, B, Bibow, S, Strotz, D, Orts, J, Guntert, P, Riek, R. 登録日 2015-03-13 公開日 2015-08-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 A Structural Ensemble for the Enzyme Cyclophilin Reveals an Orchestrated Mode of Action at Atomic Resolution. Angew.Chem.Int.Ed.Engl., 54, 2015
2MS4	Cyclophilin a complexed with a fragment of crk-ii 分子名称: Peptide, Peptidyl-prolyl cis-trans isomerase A 著者 Jankowski, W, Saleh, T, Rossi, P, Kalodimos, C. 登録日 2014-07-22 公開日 2015-09-09 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway. Nat.Chem.Biol., 12, 2016
2MQ6	Solution structure of Y125F mutant of eRF1 N-domain 分子名称: Eukaryotic peptide chain release factor subunit 1 著者 Pillay, S, Li, Y, Wong, L, Pervushin, K. 登録日 2014-06-12 公開日 2015-06-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural insights of eRF1 mutants and their correlation with stop codon recognition To be Published
2N3O	Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from viral internal ribosomal entry site RNA 分子名称: Polypyrimidine tract-binding protein 1, RNA (5'-R(*GP*GP*GP*AP*CP*CP*UP*GP*GP*UP*CP*UP*UP*UP*CP*CP*AP*GP*GP*UP*CP*CP*C)-3') 著者 Maris, C, Jayne, S.F, Damberger, F.F, Ravindranathan, S, Allain, F.H.-T. 登録日 2015-06-08 公開日 2016-08-10 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 C-terminal helix folding upon pyrimidine-rich hairpin binding to PTB RRM1. Implications for PTB function in Encephalomyocarditis virus IRES activity. To be Published
2NLU	Domain-Swapped Dimer of the PWWP Module of Human Hepatoma-derived Growth Factor 分子名称: Hepatoma-derived growth factor 著者 Sue, S.C, Lee, W.T, Huang, T.H. 登録日 2006-10-20 公開日 2007-09-04 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 PWWP module of human hepatoma-derived growth factor forms a domain-swapped dimer with much higher affinity for heparin J.Mol.Biol., 367, 2007
2N3K	Human Brd4 ET domain in complex with MLV Integrase C-term 分子名称: Bromodomain-containing protein 4, MLV integrase 著者 Crowe, B.L, Foster, M.P. 登録日 2015-06-03 公開日 2016-03-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of the Brd4 ET domain bound to a C-terminal motif from gamma-retroviral integrases reveals a conserved mechanism of interaction. Proc.Natl.Acad.Sci.USA, 113, 2016
2P2R	Crystal structure of the third KH domain of human Poly(C)-Binding Protein-2 in complex with C-rich strand of human telomeric DNA 分子名称: 6-AMINOPYRIMIDIN-2(1H)-ONE, C-rich strand of human telomeric DNA, Poly(rC)-binding protein 2 著者 James, T.L, Stroud, R.M, Du, Z, Fenn, S, Tjhen, R, Lee, J.K. 登録日 2007-03-07 公開日 2007-06-12 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res., 35, 2007
2PA2	Crystal structure of human Ribosomal protein L10 core domain 分子名称: 60S ribosomal protein L10, POTASSIUM ION 著者 Nishimura, M, Kaminishi, T, Takemoto, C, Kawazoe, M, Yoshida, T, Tanaka, A, Sugano, S, Shirouzu, M, Ohkubo, T, Yokoyama, S, Kobayashi, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-27 公開日 2008-03-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of Human Ribosomal Protein L10 Core Domain Reveals Eukaryote-Specific Motifs in Addition to the Conserved Fold J.Mol.Biol., 377, 2008
2P6N	Human DEAD-box RNA helicase DDX41, helicase domain 分子名称: ATP-dependent RNA helicase DDX41 著者 Karlberg, T, Ogg, D, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) 登録日 2007-03-19 公開日 2007-04-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Comparative Structural Analysis of Human DEAD-Box RNA Helicases. Plos One, 5, 2010
2P9I	Crystal Structure of bovine Arp2/3 Complex co-crystallized with ADP and crosslinked with gluteraldehyde 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein 2, Actin-like protein 3, ... 著者 Nolen, B.J, Pollard, T.D. 登録日 2007-03-26 公開日 2007-05-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex. Mol.Cell, 26, 2007
2LBD	LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO ALL-TRANS RETINOIC ACID 分子名称: RETINOIC ACID, RETINOIC ACID RECEPTOR GAMMA 著者 Renaud, J.-P, Rochel, N, Ruff, M, Moras, D, Structural Proteomics in Europe (SPINE) 登録日 1997-08-19 公開日 1997-11-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. Nature, 378, 1995
2LEH	Solution structure of the core SMN-Gemin2 complex 分子名称: Survival motor neuron protein, Survival of motor neuron protein-interacting protein 1 著者 Sarachan, K.L, Valentine, K, Gupta, K, Moorman, V, Gledhill, J, Bernens, M, Tommos, C, Wand, A.J, Van Duyne, G. 登録日 2011-06-15 公開日 2012-06-27 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of the core SMN-Gemin2 complex. Biochem.J., 445, 2012
2P9K	Crystal structure of bovine Arp2/3 complex co-crystallized with ATP and crosslinked with glutaraldehyde 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-like protein 2, Actin-like protein 3, ... 著者 Nolen, B.J, Pollard, T.D. 登録日 2007-03-26 公開日 2007-05-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex. Mol.Cell, 26, 2007
2PSN	Crystal structure of enolase1 分子名称: Alpha-enolase, MAGNESIUM ION, PHOSPHATE ION 著者 Hyo, J.K, Seung, J.K, Sang, J.C. 登録日 2007-05-07 公開日 2008-05-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Enolase1 alpha To be Published
2L2L	Solution structure of the coiled-coil complex between MBD2 and p66alpha 分子名称: Methyl-CpG-binding domain protein 2, Transcriptional repressor p66-alpha 著者 Williams Jr, D.C, Scarsdale Jr, N. 登録日 2010-08-20 公開日 2011-05-04 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 p66Alpha-MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2-NuRD complex. Proc.Natl.Acad.Sci.USA, 108, 2011
2LF7	Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to Q436 分子名称: Transcription factor ETV6 著者 Coyne III, H, Green, S.M, Graves, B.J, Mcintosh, L.P. 登録日 2011-06-28 公開日 2012-05-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain. J.Mol.Biol., 421, 2012
2KZU	DAXX helical bundle (DHB) domain / Rassf1C complex 分子名称: Death-associated protein 6, Ras association (RalGDS/AF-6) domain family 1 著者 Escobar-Cabrera, E, Lau, D.K.W, Giovinazzi, S, Ishov, A.M, McIntosh, L.P. 登録日 2010-06-25 公開日 2010-12-15 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Characterization of the DAXX N-Terminal Helical Bundle Domain and Its Complex with Rassf1C. Structure, 18, 2010
2LGT	Backbone 1H, 13C, and 15N Chemical Shift Assignments for QFM(Y)F 分子名称: Eukaryotic peptide chain release factor subunit 1 著者 Wong, L.E, Li, Y, Pillay, S, Pervushin, K. 登録日 2011-08-02 公開日 2012-03-14 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Selectivity of stop codon recognition in translation termination is modulated by multiple conformations of GTS loop in eRF1 Nucleic Acids Res., 2012
2PHE	Model for VP16 binding to PC4 分子名称: Alpha trans-inducing protein, TRANSCRIPTIONAL COACTIVATOR PC4 著者 Jonker, H.R.A, Wechselberger, R.W, Boelens, R, Folkers, G.E, Kaptein, R. 登録日 2007-04-11 公開日 2007-04-24 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural Properties of the Promiscuous VP16 Activation Domain Biochemistry, 44, 2005

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