2N3K
Human Brd4 ET domain in complex with MLV Integrase C-term
Summary for 2N3K
| Entry DOI | 10.2210/pdb2n3k/pdb |
| NMR Information | BMRB: 25649 |
| Descriptor | Bromodomain-containing protein 4, MLV integrase (2 entities in total) |
| Functional Keywords | brd4 et, mlv integrase, protein binding |
| Biological source | Homo sapiens (human) More |
| Cellular location | Nucleus: O60885 |
| Total number of polymer chains | 2 |
| Total formula weight | 12150.96 |
| Authors | Crowe, B.L.,Foster, M.P. (deposition date: 2015-06-03, release date: 2016-03-02, Last modification date: 2023-06-14) |
| Primary citation | Crowe, B.L.,Larue, R.C.,Yuan, C.,Hess, S.,Kvaratskhelia, M.,Foster, M.P. Structure of the Brd4 ET domain bound to a C-terminal motif from gamma-retroviral integrases reveals a conserved mechanism of interaction. Proc.Natl.Acad.Sci.USA, 113:2086-2091, 2016 Cited by PubMed: 26858406DOI: 10.1073/pnas.1516813113 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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