8K5C
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8K5D
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8K5B
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8ODU
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![BU of 8odu by Molmil](/molmil-images/mine/8odu) | Chaetomium thermophilum Get1/Get2 heterotetramer in complex with a Get3 dimer (amphipol) | 分子名称: | ATPase GET3, Protein GET2,Protein GET1, ZINC ION | 著者 | McDowell, M.A, Wild, K, Sinning, I. | 登録日 | 2023-03-09 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | The GET insertase exhibits conformational plasticity and induces membrane thinning. Nat Commun, 14, 2023
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8K0B
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8ODV
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![BU of 8odv by Molmil](/molmil-images/mine/8odv) | Chaetomium thermophilum Get1/Get2 heterotetramer in complex with a Get3 dimer (nanodisc) | 分子名称: | ATPase GET3, Protein GET2,Protein GET1, ZINC ION | 著者 | McDowell, M.A, Wild, K, Sinning, I. | 登録日 | 2023-03-09 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | The GET insertase exhibits conformational plasticity and induces membrane thinning. Nat Commun, 14, 2023
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8HW1
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![BU of 8hw1 by Molmil](/molmil-images/mine/8hw1) | Far-red light-harvesting complex of Antarctic alga Prasiola crispa | 分子名称: | (1S)-4-[(1E,3Z,5E,7E,9E,11E,13E,15E,17E)-3-(hydroxymethyl)-7,12,16-trimethyl-18-[(1R,4S)-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethyl-cyclohex-3-en-1-ol, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, CHLOROPHYLL A, ... | 著者 | Kosugi, M, Kawasaki, M, Shibata, Y, Moriya, T, Adachi, N, Senda, T. | 登録日 | 2022-12-28 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Uphill energy transfer mechanism for photosynthesis in an Antarctic alga. Nat Commun, 14, 2023
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8HXS
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![BU of 8hxs by Molmil](/molmil-images/mine/8hxs) | Small_spotted catshark CD8alpha | 分子名称: | T-cell surface glycoprotein CD8 alpha chain | 著者 | Wang, J, Zou, J. | 登録日 | 2023-01-05 | 公開日 | 2023-02-22 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The first crystal structure of CD8 alpha alpha from a cartilaginous fish. Front Immunol, 14, 2023
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3ZOX
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![BU of 3zox by Molmil](/molmil-images/mine/3zox) | Crystal Structure of N64Del Mutant of Nitrosomonas europaea Cytochrome c552 (monoclinic space group) | 分子名称: | CYTOCHROME C-552, HEME C | 著者 | Hersleth, H.-P, Can, M, Krucinska, J, Zoppellaro, G, Andersen, N.H, Wedekind, J.E, Andersson, K.K, Bren, K.L. | 登録日 | 2013-02-26 | 公開日 | 2013-08-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Characterization of Nitrosomonas Europaea Cytochrome C-552 Variants with Marked Differences in Electronic Structure. Chembiochem, 14, 2013
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8HMF
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![BU of 8hmf by Molmil](/molmil-images/mine/8hmf) | head module state 2 of Tetrahymena IFT-A | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ... | 著者 | Ma, Y, Wu, J, Lei, M. | 登録日 | 2022-12-03 | 公開日 | 2023-06-14 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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7AYC
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![BU of 7ayc by Molmil](/molmil-images/mine/7ayc) | Crystal Structure of human mitochondrial 2-Enoyl Thioester Reductase (MECR) with single mutation G165Q | 分子名称: | CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase, mitochondrial | 著者 | Rahman, M.T, Koski, M.K, Autio, K.J, Kastaniotis, A.J, Wierenga, R.K, Hiltunen, J.K. | 登録日 | 2020-11-12 | 公開日 | 2022-06-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration. Nat Commun, 14, 2023
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7AYB
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![BU of 7ayb by Molmil](/molmil-images/mine/7ayb) | Crystal Structure of wild type human mitochondrial 2-Enoyl Thioester Reductase (MECR) | 分子名称: | ACETIC ACID, CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase, ... | 著者 | Rahman, M.T, Koski, M.K, Autio, K.J, Kastaniotis, A.J, Wierenga, R.K, Hiltunen, J.K. | 登録日 | 2020-11-12 | 公開日 | 2022-06-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration. Nat Commun, 14, 2023
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4AH7
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![BU of 4ah7 by Molmil](/molmil-images/mine/4ah7) | Structure of Wild Type Stapylococcus aureus N-acetylneuraminic acid lyase in complex with pyruvate | 分子名称: | N-ACETYLNEURAMINATE LYASE | 著者 | Timms, N, Poyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A. | 登録日 | 2012-02-03 | 公開日 | 2013-01-23 | 最終更新日 | 2013-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy. Chembiochem, 14, 2013
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8KI1
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![BU of 8ki1 by Molmil](/molmil-images/mine/8ki1) | Crystal structure of the holo form of the hemophore HasA from Pseudomonas protegens Pf-5 | 分子名称: | GLYCEROL, Heme acquisition protein HasAp, PHOSPHATE ION, ... | 著者 | Shisaka, Y, Inaba, H, Sugimoto, H, Shoji, O. | 登録日 | 2023-08-22 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom. Rsc Adv, 14, 2024
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8KI0
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![BU of 8ki0 by Molmil](/molmil-images/mine/8ki0) | Crystal structure of the hemophore HasA from Pseudomonas protegens Pf-5 capturing Fe-tetraphenylporphyrin | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Heme acquisition protein HasAp, ... | 著者 | Shisaka, Y, Inaba, H, Sugimoto, H, Shoji, O. | 登録日 | 2023-08-22 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom. Rsc Adv, 14, 2024
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8OEJ
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![BU of 8oej by Molmil](/molmil-images/mine/8oej) | Extended RPA-DNA nucleoprotein filament | 分子名称: | RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ... | 著者 | Madru, C, Martinez-Carranza, M, Sauguet, L. | 登録日 | 2023-03-10 | 公開日 | 2023-05-10 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (7.96 Å) | 主引用文献 | DNA-binding mechanism and evolution of replication protein A. Nat Commun, 14, 2023
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8OG5
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![BU of 8og5 by Molmil](/molmil-images/mine/8og5) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 1 | 分子名称: | 1,2-ETHANEDIOL, 5-(2-fluorophenyl)-2,3-dihydroimidazo[2,1-a]isoquinoline, ACETATE ION, ... | 著者 | Schroeder, M, Vulpetti, A, Renatus, M. | 登録日 | 2023-03-19 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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8OEL
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![BU of 8oel by Molmil](/molmil-images/mine/8oel) | Condensed RPA-DNA nucleoprotein filament | 分子名称: | RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ... | 著者 | Madru, C, Martinez-Carranza, M, Sauguet, L. | 登録日 | 2023-03-10 | 公開日 | 2023-06-14 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (8.24 Å) | 主引用文献 | DNA-binding mechanism and evolution of replication protein A. Nat Commun, 14, 2023
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8OG6
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![BU of 8og6 by Molmil](/molmil-images/mine/8og6) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 1 | 分子名称: | 5-(2-fluorophenyl)-2,3-dihydroimidazo[2,1-a]isoquinoline, ACETATE ION, DDB1- and CUL4-associated factor 1 | 著者 | Schroeder, M, Vulpetti, A, Renatus, M. | 登録日 | 2023-03-19 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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8OG8
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![BU of 8og8 by Molmil](/molmil-images/mine/8og8) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 3 | 分子名称: | 1,2-ETHANEDIOL, 5-(2-methyl-1-phenyl-propan-2-yl)imidazo[2,1-a]isoquinoline, ACETATE ION, ... | 著者 | Schroeder, M, Vulpetti, A, Renatus, M. | 登録日 | 2023-03-19 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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8OGC
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![BU of 8ogc by Molmil](/molmil-images/mine/8ogc) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 11 | 分子名称: | 1,2-ETHANEDIOL, 1-[4-[4-(2-azanylethylamino)-2-[1-(4-chlorophenyl)cyclopentyl]quinazolin-7-yl]piperazin-1-yl]ethanone, ACETATE ION, ... | 著者 | Schroeder, M, Vulpetti, A, Renatus, M. | 登録日 | 2023-03-19 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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8OG7
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![BU of 8og7 by Molmil](/molmil-images/mine/8og7) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 2 | 分子名称: | (4~{R})-4-[3-(4-chloranylphenoxy)phenyl]pyrrolidin-2-imine, 1,2-ETHANEDIOL, ACETATE ION, ... | 著者 | Schroeder, M, Vulpetti, A, Renatus, M. | 登録日 | 2023-03-19 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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8OGA
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![BU of 8oga by Molmil](/molmil-images/mine/8oga) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 6 | 分子名称: | 1,2-ETHANEDIOL, 5-[1-(4-methoxyphenyl)cyclopropyl]-8-(4-methylpiperazin-1-yl)-2,3-dihydroimidazo[2,1-a]isoquinoline, DDB1- and CUL4-associated factor 1, ... | 著者 | Schroeder, M, Vulpetti, A, Renatus, M. | 登録日 | 2023-03-19 | 公開日 | 2023-06-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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8OG9
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![BU of 8og9 by Molmil](/molmil-images/mine/8og9) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 4 | 分子名称: | 5-[1-(4-chlorophenyl)cyclopropyl]imidazo[2,1-a]isoquinoline, DDB1- and CUL4-associated factor 1 | 著者 | Schroeder, M, Vulpetti, A, Renatus, M. | 登録日 | 2023-03-19 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.945 Å) | 主引用文献 | Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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8OGB
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![BU of 8ogb by Molmil](/molmil-images/mine/8ogb) | Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 8 | 分子名称: | 1,2-ETHANEDIOL, DDB1- and CUL4-associated factor 1, DIMETHYL SULFOXIDE, ... | 著者 | Schroeder, M, Vulpetti, A, Renatus, M. | 登録日 | 2023-03-19 | 公開日 | 2023-06-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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