PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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4NNO	Crystal Structure of Manganese ABC transporter substrate-binding protein MntC from Staphylococcus Aureus bound to a Zinc ion 分子名称: Lipoprotein, ZINC ION 著者 Rouge, L, Ahuja, S, Sudhamsu, J. 登録日 2013-11-18 公開日 2014-11-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.174 Å) 主引用文献 Structural analysis of bacterial ABC transporter inhibition by an antibody fragment. Structure, 23, 2015
6AXK	Crystal structure of Fab311 complex 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACE-ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-ASN-PRO-ASN, Fab311 heavy chain, ... 著者 Oyen, D, Wilson, I.A. 登録日 2017-09-07 公開日 2017-11-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.103 Å) 主引用文献 Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8U5B	Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain and sFab COP-1 分子名称: COP-1 sFab Heavy Chain, COP-1 sFab Light Chain, Claudin-4, ... 著者 Vecchio, A.J. 登録日 2023-09-12 公開日 2023-09-27 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (5.3 Å) 主引用文献 Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. Commun Biol, 7, 2024
4NWU	Crystal structure of APE1551, an anti-human NGF Fab with a nine amino acid insertion in CDR H1 分子名称: APE1551 Ab Fab heavy chain, APE1551 Ab Fab light chain 著者 Verdino, P, Stanfield, R.L, Wilson, I.A. 登録日 2013-12-06 公開日 2014-10-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.602 Å) 主引用文献 Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. J.Biol.Chem., 289, 2014
8QH1	Crystal structure of the SARS-CoV-2 RBD from the Omicron BA4 variant with the antibody Cv2.3194 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cv2.3194 heavy chain, IGK@ protein, ... 著者 Fernandez, I, Rey, F.A. 登録日 2023-09-06 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Pan-neutralizing antibody isolated from a COVID patient To Be Published
8QH0	Crystal structure of the SARS-CoV-2 RBD with the antibody Cv2.3194 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cv2.3194 Heavy chain, GLYCEROL, ... 著者 Fernandez, I, Rey, F.A. 登録日 2023-09-06 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 A broadly neutralizing antibody against SARS-CoV-2 Omicron variants To Be Published
3NZH	Crystal structure of anti-emmprin antibody 5F6 FAB 分子名称: 5F6 HEAVY CHAIN, 5F6 LIGHT CHAIN, COBALT (II) ION, ... 著者 Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. 登録日 2010-07-16 公開日 2011-07-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of anti-emmprin antibody 5F6 FAB To be Published
4NWT	Crystal structure of the anti-human NGF Fab APE1531 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, APE1531 Ab Fab heavy chain, ... 著者 Verdino, P, Stanfield, R.L, Wilson, I.A. 登録日 2013-12-06 公開日 2014-10-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. J.Biol.Chem., 289, 2014
8U4V	Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-1, and Nanobody 分子名称: Anti-fab nanobody, COP-1 sFab Heavy Chain, COP-1 sFab Light Chain, ... 著者 Vecchio, A.J. 登録日 2023-09-11 公開日 2023-10-25 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.99 Å) 主引用文献 Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. Commun Biol, 7, 2024
7SN0	Crystal structure of spike protein receptor binding domain of escape mutant SARS-CoV-2 from immunocompromised patient (d146*) in complex with human receptor ACE2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Pan, J, Abraham, J, Clark, S. 登録日 2021-10-27 公開日 2021-12-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain. Science, 375, 2022
6GKS	X-ray structure determined from recombinant Charcot-Leyden crystal 分子名称: GLYCEROL, Galectin-10 著者 Verstraete, K, Verschueren, K, Savvides, S.N. 登録日 2018-05-21 公開日 2019-06-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019
6GKQ	X-ray structure determined from ex vivo Charcot-Leyden crystal 分子名称: GLYCEROL, Galectin-10 著者 Verstraete, K, Verschueren, K, Savvides, S.N. 登録日 2018-05-21 公開日 2019-06-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019
6FGB	Human FcRn extra-cellular domain complexed with Fab fragment of Rozanolixizumab 分子名称: 1519.g57- Heavy chain, 1519.g57- Light chain, Beta-2-microglobulin, ... 著者 Sarkar, K, Ceska, T, Meier, C. 登録日 2018-01-10 公開日 2018-08-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration. MAbs, 10, 2018
7MLH	Crystal structure of human IgE (2F10) in complex with Der p 2.0103 分子名称: CHLORIDE ION, Der p 2 variant 3, IgE Heavy chain, ... 著者 Khatri, K, Kapingidza, A.B, Richardson, C.M, Vailes, L.D, Wunschmann, S, Dolamore, C, Chapman, M.D, Smith, S.A, Pomes, A, Chruszcz, M. 登録日 2021-04-28 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo. Pnas Nexus, 1, 2022
4KTD	Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE136, from non-human primate 分子名称: GE136 Heavy Chain Fab, GE136 Light Chain Fab, GLYCEROL, ... 著者 Poulsen, C, Tran, K, Standfield, R, Wyatt, R.T. 登録日 2013-05-20 公開日 2014-02-05 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc.Natl.Acad.Sci.USA, 111, 2014
4KTE	Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE148, from non-human primate 分子名称: GE148 Heavy Chain Fab, GE148 Light Chain Fab, GLYCEROL, ... 著者 Poulsen, C, Tran, K, Stanfield, R, Wyatt, R.T. 登録日 2013-05-20 公開日 2014-02-05 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc.Natl.Acad.Sci.USA, 111, 2014
4OKV	Crystal structure of anopheline anti-platelet protein with Fab antibody 分子名称: Anti-platelet aggregation protein, heavy chain of 8H7 mAb, light chain of 8H7 mAb 著者 Park, S.Y, Sugiyama, K. 登録日 2014-01-23 公開日 2014-04-30 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 The crystal structure of anopheles anti-platelet protein, a powerful anti-coagulant, in complex with an antibody To be Published
4R90	Anti CD70 Llama glama Fab 27B3 分子名称: Anti CD70 Llama glama Fab 27B3 Heavy chain, Anti CD70 Llama glama Fab 27B3 Light chain, CALCIUM ION, ... 著者 Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. 登録日 2014-09-03 公開日 2015-06-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.746 Å) 主引用文献 Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
4R96	Structure of a Llama Glama Fab 48A2 against human cMet 分子名称: Llama glama Fab 48A2 against human cMet H chain, Llama glama Fab 48A2 against human cMet L chain 著者 Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. 登録日 2014-09-03 公開日 2015-06-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
4HXB	Crystal structure of 6B9 FAB 分子名称: 6B9 FAB HEAVY CHAIN, 6B9 FAB LIGHT CHAIN, CALCIUM ION 著者 Johal, A.R, Jarrell, H.C, Khieu, N.H, Letts, J.A, Landry, R.C, Jachymek, W, Yang, Q, Jennings, H.J, Brisson, J.R, Evans, S.V. 登録日 2012-11-09 公開日 2013-07-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The antigen-binding site of an N-propionylated polysialic acid-specific antibody protective against group B meningococci is consistent with extended epitopes. Glycobiology, 23, 2013
4HXA	Crystal structure of 13D9 FAB 分子名称: 13D9 FAB HEAVY CHAIN, 13D9 FAB LIGHT CHAIN 著者 Johal, A.R, Jarrell, H.C, Khieu, N.H, Letts, J.A, Landry, R.C, Jachymek, W, Yang, Q, Jennings, H.J, Brisson, J.R, Evans, S.V. 登録日 2012-11-09 公開日 2013-07-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 The antigen-binding site of an N-propionylated polysialic acid-specific antibody protective against group B meningococci is consistent with extended epitopes. Glycobiology, 23, 2013
8R1D	SD1-3 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SD1-3 Fab Heavy Chain, SD1-3 Fab Light Chain, ... 著者 Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. 登録日 2023-11-01 公開日 2024-03-13 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (2.37 Å) 主引用文献 The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86. Nat Commun, 15, 2024
6WHK	Minimally mutated anti-influenza broadly neutralizing antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Fab Heavy Chain, ... 著者 Bajic, G, Schmidt, A.G. 登録日 2020-04-08 公開日 2021-04-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Minimally mutated anti-influenza broadly neutralizing antibody To Be Published
6WJU	Fab Fragment of Anti-human LAG3 antibody (4A10) 分子名称: 4A10 Fab Heavy Chain, 4A10 Fab Light Chain 著者 Agnihotri, P, Mishra, A.K, Mariuzza, R.A. 登録日 2020-04-14 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Fab Fragment of Anti-human LAG3 antibody To Be Published
6WK4	Fab Fragment of Anti-human LAG3 antibody (13E2) 分子名称: 13E2 Fab Heavy Chain, 13E2 Fab Light Chain, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL 著者 Agnihotri, P, Mishra, A.K, Mariuzza, R.A. 登録日 2020-04-15 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Fab Fragment of Anti-human LAG3 antibody To Be Published

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