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7E6A
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BU of 7e6a by Molmil
Crystal structure of cysteine desulfurase SufS C361A from Bacillus subtilis
分子名称: 1,2-ETHANEDIOL, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ...
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2021-02-22
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
7E6C
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Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS C361A from Bacillus subtilis
分子名称: (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, 1,2-ETHANEDIOL, Cysteine desulfurase SufS, ...
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2021-02-22
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
7E6B
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BU of 7e6b by Molmil
Crystal structure of PMP-bound form of cysteine desulfurase SufS C361A from Bacillus subtilis
分子名称: 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Cysteine desulfurase SufS, ...
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2021-02-22
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
7E6D
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BU of 7e6d by Molmil
Crystal structure of cysteine desulfurase SufS R376A from Bacillus subtilis
分子名称: Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2021-02-22
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
7E6F
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BU of 7e6f by Molmil
Crystal structure of PMP-bound form of cysteine desulfurase SufS R376A from Bacillus subtilis in L-cycloserine-inhibition
分子名称: 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Cysteine desulfurase SufS, ...
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2021-02-22
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
6P4V
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BU of 6p4v by Molmil
1.65 Angstrom ternary complex of Deoxyhypusine synthase with cofactor NAD and spermidine mimic inhibitor GC7
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-GUANIDINIUM-7-AMINOHEPTANE, Deoxyhypusine synthase, ...
著者Klein, M.G, Ambrus-Aikelin, G.
登録日2019-05-28
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase.
J.Med.Chem., 63, 2020
7SSB
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BU of 7ssb by Molmil
Co-structure of PKG1 regulatory domain with compound 33
分子名称: 4-({(2S,3S)-3-[(1S)-1-(3,5-dichlorophenyl)-2-hydroxyethoxy]-2-phenylpiperidin-1-yl}methyl)-3-nitrobenzoic acid, cGMP-dependent protein kinase 1
著者Fischmann, T.O.
登録日2021-11-10
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Optimization and Mechanistic Investigations of Novel Allosteric Activators of PKG1 alpha.
J.Med.Chem., 65, 2022
5JH9
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BU of 5jh9 by Molmil
Crystal structure of prApe1
分子名称: CACODYLATE ION, Vacuolar aminopeptidase 1, ZINC ION
著者Noda, N.N, Adachi, W, Inagaki, F.
登録日2016-04-20
公開日2016-06-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates
Cell Rep, 16, 2016
3OH6
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BU of 3oh6 by Molmil
AlkA Undamaged DNA Complex: Interrogation of a C:G base pair
分子名称: 5'-D(*GP*AP*CP*AP*(BRU)P*GP*AP*AP*(BRU)P*GP*CP*C)-3', 5'-D(*GP*CP*AP*TP*TP*CP*AP*TP*GP*TP*C)-3', DNA-3-methyladenine glycosylase 2
著者Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
登録日2010-08-17
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.894 Å)
主引用文献Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
J.Biol.Chem., 285, 2010
7SRS
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BU of 7srs by Molmil
5-HT2B receptor bound to LSD in complex with beta-arrestin1 obtained by cryo-electron microscopy (cryoEM)
分子名称: (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 2B, ...
著者Barros-Alvarez, X, Cao, C, Panova, O, Roth, B.L, Skiniotis, G.
登録日2021-11-08
公開日2022-09-21
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.
Neuron, 110, 2022
7SRQ
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5-HT2B receptor bound to LSD obtained by cryo-electron microscopy (cryoEM)
分子名称: (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 2B
著者Barros-Alvarez, X, Cao, C, Panova, O, Roth, B.L, Skiniotis, G.
登録日2021-11-08
公開日2022-09-21
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.
Neuron, 110, 2022
3NRK
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BU of 3nrk by Molmil
The crystal structure of the leptospiral hypothetical protein LIC12922
分子名称: LIC12922
著者Giuseppe, P.O, Atzingen, M.V, Nascimento, A.L.T.O, Zanchin, N.I.T, Guimaraes, B.G.
登録日2010-06-30
公開日2010-11-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The crystal structure of the leptospiral hypothetical protein LIC12922 reveals homology with the periplasmic chaperone SurA.
J.Struct.Biol., 173, 2011
7SZU
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BU of 7szu by Molmil
Crystal structure of Pepper RNA aptamer in complex with HBC ligand and Fab BL3-6
分子名称: 4-[(~{Z})-1-cyano-2-[4-[2-hydroxyethyl(methyl)amino]phenyl]ethenyl]benzenecarbonitrile, BL3-6 Fab heavy chain, BL3-6 Fab light chain, ...
著者Rees, H.C, Piccirilli, J.A.
登録日2021-11-29
公開日2022-07-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural Basis for Fluorescence Activation by Pepper RNA.
Acs Chem.Biol., 17, 2022
7SRR
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BU of 7srr by Molmil
5-HT2B receptor bound to LSD in complex with heterotrimeric mini-Gq protein obtained by cryo-electron microscopy (cryoEM)
分子名称: (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 5-hydroxytryptamine receptor 2B, G protein subunit q (Gi2-mini-Gq chimera), ...
著者Barros-Alvarez, X, Kim, K, Panova, O, Cao, C, Roth, B.L, Skiniotis, G.
登録日2021-11-08
公開日2022-09-21
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.
Neuron, 110, 2022
5JGE
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BU of 5jge by Molmil
Crystal structure of Atg19 coiled-coil complexed with Ape1 propeptide
分子名称: Ape1 propeptide, Autophagy-related protein 19
著者Watanabe, Y, Noda, N.N.
登録日2016-04-20
公開日2016-06-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates
Cell Rep, 16, 2016
5JLD
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BU of 5jld by Molmil
Crystal Structure of Arginyl-tRNA Synthetase from Plasmodium falciparum (PfRRS)
分子名称: Arginyl-tRNA synthetase, putative
著者Jain, V, Manickam, Y, Sharma, A.
登録日2016-04-27
公開日2016-08-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dimerization of Arginyl-tRNA Synthetase by Free Heme Drives Its Inactivation in Plasmodium falciparum
Structure, 24, 2016
5J75
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BU of 5j75 by Molmil
Fluorogen Activating Protein AM2.2 in complex with ML342
分子名称: N,4-dimethyl-N-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}benzene-1-sulfonamide, PHOSPHATE ION, scFv AM2.2
著者Stanfield, R.L, Wilson, I.A, Wu, Y.
登録日2016-04-05
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair.
J Biomol Screen, 21, 2016
3OH9
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BU of 3oh9 by Molmil
AlkA Undamaged DNA Complex: Interrogation of a T:A base pair
分子名称: 5'-D(*AP*CP*AP*(BRU)P*GP*AP*AP*(BRU)P*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*TP*TP*CP*AP*TP*GP*T)-3', DNA-3-methyladenine glycosylase 2
著者Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
登録日2010-08-17
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
J.Biol.Chem., 285, 2010
6VBP
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BU of 6vbp by Molmil
Crystal structure of anti-HIV-1 antibody DH815 bound to gp120 V2 peptide
分子名称: CHLORIDE ION, DH815 heavy chain, DH815 light chain, ...
著者Janus, B.M, Ofek, G.
登録日2019-12-19
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
JCI Insight, 5, 2020
5JGF
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BU of 5jgf by Molmil
Crystal structure of mApe1
分子名称: Vacuolar aminopeptidase 1, ZINC ION
著者Noda, N.N, Adachi, W, Inagaki, F.
登録日2016-04-20
公開日2016-06-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates
Cell Rep, 16, 2016
5XYV
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BU of 5xyv by Molmil
Crystal structure of drosophila melanogaster Rhino chromoshadow domain in complex with Deadlock N-terminal domain
分子名称: Protein deadlock, RHINO
著者Yu, B.W, Huang, Y.
登録日2017-07-10
公開日2018-06-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into Rhino-Deadlock complex for germline piRNA cluster specification
EMBO Rep., 19, 2018
5JHC
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BU of 5jhc by Molmil
Crystal structure of the self-assembled propeptides from Ape1
分子名称: Vacuolar aminopeptidase 1
著者Yamasaki, A, Noda, N.N.
登録日2016-04-20
公開日2016-06-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates
Cell Rep, 16, 2016
6P07
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BU of 6p07 by Molmil
Spastin hexamer in complex with substrate
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Sandate, C.R, Szyk, A, Zehr, E, Roll-Mecak, A, Lander, G.C.
登録日2019-05-16
公開日2019-06-12
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献An allosteric network in spastin couples multiple activities required for microtubule severing.
Nat.Struct.Mol.Biol., 26, 2019
3OMW
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BU of 3omw by Molmil
Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II
分子名称: CG14216
著者Zhang, Y, Zhang, M, Zhang, Y.
登録日2010-08-27
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8701 Å)
主引用文献Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue.
Biochem.J., 434, 2011
6VBQ
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BU of 6vbq by Molmil
Crystal structure of anti-HIV-1 antibody DH822 bound to gp120 V2 peptide
分子名称: DH822 heavy chain, DH822 light chain, Envelope glycoprotein gp160
著者Janus, B.M, Ofek, G.
登録日2019-12-19
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.116 Å)
主引用文献HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
JCI Insight, 5, 2020

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