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8T0Z
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Human liver-type glutaminase (K253A) with L-Gln, filamentous form
分子名称: GLUTAMINE, Glutaminase liver isoform, mitochondrial
著者Feng, S, Aplin, C, Nguyen, T.-T.T, Milano, S.K, Cerione, R.A.
登録日2023-06-01
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Filament formation drives catalysis by glutaminase enzymes important in cancer progression.
Nat Commun, 15, 2024
8T0Y
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BU of 8t0y by Molmil
TRPV1 in nanodisc bound with one LPA in one monomer
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, ...
著者Arnold, W.R, Cheng, Y.
登録日2023-06-01
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
8T0V
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Closed state of lysine 5,6-aminomutase from Thermoanaerobacter tengcongensis
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, D-lysine 5,6-aminomutase alpha subunit, ...
著者Tian, S, Voss, P, Pham, K, Klose, T.
登録日2023-06-01
公開日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Catalysis in Motion: Large-Scale Domain Shift Enables Co-C Bond Homolysis in Lysine 5,6-Aminomutase
To Be Published
8T0T
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Structure of Compound 4 bound to human ALDH1A1
分子名称: 1-(4-{6-fluoro-3-[4-(methanesulfonyl)piperazine-1-carbonyl]quinolin-4-yl}phenyl)cyclopropane-1-carbonitrile, Aldehyde dehydrogenase 1A1, CHLORIDE ION, ...
著者Hurley, T.D.
登録日2023-06-01
公開日2024-05-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Development of substituted benzimidazoles as inhibitors of human aldehyde dehydrogenase 1A isoenzymes.
Chem.Biol.Interact., 391, 2024
8T0S
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Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2
著者Wang, C, Shaw, G.X, Shi, G, Ji, X.
登録日2023-06-01
公開日2024-06-05
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position
To be published
8T0R
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Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state (full helix)
分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
登録日2023-06-01
公開日2024-05-01
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8T0Q
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Open state of lysine 5,6-aminomutase from Thermoanaerobacter tengcongensis
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, D-lysine 5,6-aminomutase alpha subunit, ...
著者Tian, S, Voss, P, Pham, K, Klose, T.
登録日2023-06-01
公開日2024-07-03
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Catalysis in Motion: Large-Scale Domain Shift Enables Co-C Bond Homolysis in Lysine 5,6-Aminomutase
To Be Published
8T0P
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BU of 8t0p by Molmil
Structure of Cse4 bound to Ame1 and Okp1
分子名称: Histone H3-like centromeric protein CSE4, Inner kinetochore subunit AME1, Inner kinetochore subunit OKP1, ...
著者Deng, S, Harrison, S.C.
登録日2023-06-01
公開日2023-09-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Recognition of centromere-specific histone Cse4 by the inner kinetochore Okp1-Ame1 complex.
Embo Rep., 24, 2023
8T0O
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Fab from mAb RB2AT_87
分子名称: CHLORIDE ION, RB2AT_87 Fab Heavy chain, RB2AT_87 Fab Light chain
著者Kreutzer, A.G, Malonis, R.J, Lai, J.R, Nowick, J.S.
登録日2023-06-01
公開日2024-03-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Generation and Study of Antibodies against Two Triangular Trimers Derived from A beta.
Pept Sci (Hoboken), 116, 2024
8T0N
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BU of 8t0n by Molmil
Structure of Compound 4 bound to human ALDH1A1
分子名称: 2-methoxy-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol, Aldehyde dehydrogenase 1A1, CHLORIDE ION, ...
著者Hurley, T.D.
登録日2023-06-01
公開日2024-05-01
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Development of substituted benzimidazoles as inhibitors of human aldehyde dehydrogenase 1A isoenzymes.
Chem.Biol.Interact., 391, 2024
8T0M
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BU of 8t0m by Molmil
Proteasome 20S core particle from Pre1-1 Pre4-1 Double mutant
分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
著者Walsh Jr, R.M, Rawson, S, Schnell, H, Velez, B, Hanna, J.
登録日2023-06-01
公開日2023-09-06
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structure of the preholoproteasome reveals late steps in proteasome core particle biogenesis.
Nat.Struct.Mol.Biol., 30, 2023
8T0K
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BU of 8t0k by Molmil
Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state
分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
登録日2023-06-01
公開日2024-05-01
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8T0J
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BU of 8t0j by Molmil
Salmonella Typhimurium ArnD
分子名称: Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD
著者Sousa, M.C, Munoz-Escudero, D, Lee, M.
登録日2023-06-01
公開日2023-10-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance.
Biochemistry, 62, 2023
8T0I
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Backbone Dialkylation in Peptide Hairpins: (R)-Ethylpropylglycine variant
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Horne, W.S, Lengyel, G.A.
登録日2023-06-01
公開日2023-08-16
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
8T0H
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BU of 8t0h by Molmil
Backbone Dialkylation in Peptide Hairpins: (S)-Ethylpropylglycine variant
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Horne, W.S, Lengyel, G.A.
登録日2023-06-01
公開日2023-08-16
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
8T0G
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BU of 8t0g by Molmil
Backbone Dialkylation in Peptide Hairpins: Natural Backbone Prototype
分子名称: Immunoglobulin G-binding protein G
著者Heath, S.L, Horne, W.S, Lengyel, G.A.
登録日2023-06-01
公開日2023-08-16
実験手法SOLUTION NMR
主引用文献Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability.
Org.Biomol.Chem., 21, 2023
8T0E
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BU of 8t0e by Molmil
TRPV1 in Nanodisc not bound with lysophosphatidic acid (apo)
分子名称: (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1
著者Arnold, W.R, Cheng, Y.
登録日2023-05-31
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
8T0D
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BU of 8t0d by Molmil
Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with E269A/Y270A/K306Q triple mutation
分子名称: Integrin beta-2,Talin-1
著者Wu, J, Gao, T.
登録日2023-05-31
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation
Biorxiv, 2024
8T0C
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BU of 8t0c by Molmil
TRPV1 in Nanodisc bound with lysophosphatidic acid in all four monomers
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1
著者Arnold, W.R, Cheng, Y.
登録日2023-05-31
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
8T0B
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BU of 8t0b by Molmil
Novel Domain of Unknown Function Solved with AlphaFold
分子名称: DUF1842 domain-containing protein
著者Miller, J.E, Cascio, D, Sawaya, M.R, Yeates, T.O.
登録日2023-05-31
公開日2024-01-17
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography.
Acta Crystallogr D Struct Biol, 80, 2024
8T09
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BU of 8t09 by Molmil
Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-ethynyl-2-hydroxy-1-naphthaldehyde)
分子名称: 6-ethynyl-2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
著者Bruystens, J.G.H.
登録日2023-05-31
公開日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Acs Pharmacol Transl Sci, 6, 2023
8T08
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Preholo-Proteasome from Pre1-1 Pre4-1 Double Mutant
分子名称: Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ...
著者Walsh Jr, R.M, Rawson, S, Schnell, H, Velez, B, Hanna, J.
登録日2023-05-31
公開日2023-09-06
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the preholoproteasome reveals late steps in proteasome core particle biogenesis.
Nat.Struct.Mol.Biol., 30, 2023
8T07
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Structure of mouse Myomaker mutant-Y118A bound to Fab18G7
分子名称: 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
8T06
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Structure of mouse Myomaker mutant-R107A bound to Fab18G7
分子名称: 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
8T05
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Structure of Ciona Myomaker bound to Fab1A1
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1A1 Fab heavy chain, 1A1 Fab light chain, ...
著者Long, T, Li, X.
登録日2023-05-31
公開日2023-09-27
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023

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件を2024-07-17に公開中

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