4M20
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7YWS
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![BU of 7yws by Molmil](/molmil-images/mine/7yws) | Modified oligopeptidase B from S. proteomaculans in intermediate conformation with 3 spermine molecules at 1.7 A resolution | 分子名称: | Oligopeptidase B, SPERMINE | 著者 | Petrenko, D.E, Boyko, K.M, Nikolaeva, A.Y, Vlaskina, A.V, Mikhailova, A.G, Timofeev, V.I, Rakitina, T.V. | 登録日 | 2022-02-14 | 公開日 | 2023-01-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Elucidation of the Conformational Transition of Oligopeptidase B by an Integrative Approach Based on the Combination of X-ray, SAXS, and Essential Dynamics Sampling Simulation Crystals, 12, 2022
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7K7J
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![BU of 7k7j by Molmil](/molmil-images/mine/7k7j) | EphB6 receptor ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 6 | 著者 | Goldgur, Y, Himanen, J. | 登録日 | 2020-09-22 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.004 Å) | 主引用文献 | Structure of the EphB6 receptor ectodomain. Plos One, 16, 2021
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7YX7
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![BU of 7yx7 by Molmil](/molmil-images/mine/7yx7) | Modified oligopeptidase B from S. proteomaculans in intermediate conformation with 1 spermine molecule at 1.72 A resolution | 分子名称: | Oligopeptidase B, SPERMINE | 著者 | Petrenko, D.E, Boyko, K.M, Nikolaeva, A.Y, Vlaskina, A.V, Mikhailova, A.G, Timofeev, V.I, Rakitina, T.V. | 登録日 | 2022-02-15 | 公開日 | 2023-01-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Elucidation of the Conformational Transition of Oligopeptidase B by an Integrative Approach Based on the Combination of X-ray, SAXS, and Essential Dynamics Sampling Simulation Crystals, 12, 2022
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6U2M
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![BU of 6u2m by Molmil](/molmil-images/mine/6u2m) | Crystal structure of a HaloTag-based calcium indicator, HaloCaMP V2, bound to JF635 | 分子名称: | (1E,3S)-1-{10-[2-carboxy-5-({2-[2-(hexyloxy)ethoxy]ethyl}carbamoyl)phenyl]-7-(3-fluoroazetidin-1-yl)-5,5-dimethyldibenz o[b,e]silin-3(5H)-ylidene}-3-fluoroazetidin-1-ium, CALCIUM ION, CHLORIDE ION, ... | 著者 | Deo, C, Schreiter, E.R. | 登録日 | 2019-08-20 | 公開日 | 2020-09-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The HaloTag as a general scaffold for far-red tunable chemigenetic indicators. Nat.Chem.Biol., 17, 2021
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6EBQ
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7V61
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![BU of 7v61 by Molmil](/molmil-images/mine/7v61) | ACE2 -Targeting Monoclonal Antibody as Potent and Broad-Spectrum Coronavirus Blocker | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3E8, ... | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | 登録日 | 2021-08-18 | 公開日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker. Signal Transduct Target Ther, 6, 2021
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7Z0V
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![BU of 7z0v by Molmil](/molmil-images/mine/7z0v) | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability | 分子名称: | CHLORIDE ION, COBALT (II) ION, Nitrile hydratase, ... | 著者 | Van Wyk, J.C, Cowan, D.A, Danson, M.J, Tsekoa, T.L, Sayed, M.F, Sewell, B.T. | 登録日 | 2022-02-23 | 公開日 | 2023-03-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Engineering enhanced thermostability into the Geobacillus pallidus nitrile hydratase. Curr Res Struct Biol, 4, 2022
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6UJX
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8HXQ
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![BU of 8hxq by Molmil](/molmil-images/mine/8hxq) | Nanobody1 in complex with human BCMA ECD | 分子名称: | Nanobody1, Tumor necrosis factor receptor superfamily member 17 | 著者 | Sun, Y, Zhang, B. | 登録日 | 2023-01-05 | 公開日 | 2024-01-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity. Signal Transduct Target Ther, 8, 2023
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8HXR
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![BU of 8hxr by Molmil](/molmil-images/mine/8hxr) | Nanobody2 in complex with human BCMA ECD | 分子名称: | Nanobody2, Tumor necrosis factor receptor superfamily member 17 | 著者 | Sun, Y, Zhang, B. | 登録日 | 2023-01-05 | 公開日 | 2024-01-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity. Signal Transduct Target Ther, 8, 2023
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5UDT
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![BU of 5udt by Molmil](/molmil-images/mine/5udt) | LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, in complex with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Lactate racemization operon protein LarE, PHOSPHATE ION | 著者 | Fellner, M, Desguin, B, Hausinger, R.P, Hu, J. | 登録日 | 2016-12-28 | 公開日 | 2017-08-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.188 Å) | 主引用文献 | Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6UJY
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4M0E
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![BU of 4m0e by Molmil](/molmil-images/mine/4m0e) | Structure of human acetylcholinesterase in complex with dihydrotanshinone I | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Cheung, J, Gary, E.N, Shiomi, K, Rosenberry, T.L. | 登録日 | 2013-08-01 | 公開日 | 2013-10-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility. ACS Med Chem Lett, 4, 2013
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6UJZ
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![BU of 6ujz by Molmil](/molmil-images/mine/6ujz) | HIV-1 wild-type reverse transcriptase-DNA complex with (+)-FTC-TP | 分子名称: | MAGNESIUM ION, SULFATE ION, [[(2~{S},5~{R})-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate, ... | 著者 | Lansdon, E.B. | 登録日 | 2019-10-03 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.55642557 Å) | 主引用文献 | Elucidating molecular interactions ofL-nucleotides with HIV-1 reverse transcriptase and mechanism of M184V-caused drug resistance. Commun Biol, 2, 2019
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5UDX
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![BU of 5udx by Molmil](/molmil-images/mine/5udx) | LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, in complex with zinc | 分子名称: | Lactate racemization operon protein LarE, PHOSPHATE ION, SULFATE ION, ... | 著者 | Fellner, M, Desguin, B, Hausinger, R.P, Hu, J. | 登録日 | 2016-12-28 | 公開日 | 2017-08-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.784 Å) | 主引用文献 | Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6UK0
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![BU of 6uk0 by Molmil](/molmil-images/mine/6uk0) | HIV-1 M184V reverse transcriptase-DNA complex | 分子名称: | MAGNESIUM ION, Primer DNA, SULFATE ION, ... | 著者 | Lansdon, E.B. | 登録日 | 2019-10-03 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.75695229 Å) | 主引用文献 | Elucidating molecular interactions ofL-nucleotides with HIV-1 reverse transcriptase and mechanism of M184V-caused drug resistance. Commun Biol, 2, 2019
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3NMS
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6S5M
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![BU of 6s5m by Molmil](/molmil-images/mine/6s5m) | Strictosidine Synthase from Ophiorrhiza pumila in complex with (S)-1-n-propyl-2,3,4,9-tetrahydro-1H-beta-carboline | 分子名称: | (1~{S})-1-propyl-2,3,4,9-tetrahydro-1~{H}-pyrido[3,4-b]indole, Strictosidine synthase | 著者 | Eger, E, Sharma, M, Kroutil, W, Grogan, G. | 登録日 | 2019-07-02 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions. J.Am.Chem.Soc., 142, 2020
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6IZ5
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6S5J
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![BU of 6s5j by Molmil](/molmil-images/mine/6s5j) | Strictosidine Synthase from Ophiorrhiza pumila in complex with (S)-1-Ethyl-2,3,4,9-tetrahydro-1H-beta-carboline | 分子名称: | (1~{S})-1-ethyl-2,3,4,9-tetrahydro-1~{H}-pyrido[3,4-b]indole, Strictosidine synthase | 著者 | Eger, E, Sharma, M, Kroutil, W, Grogan, G. | 登録日 | 2019-07-01 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions. J.Am.Chem.Soc., 142, 2020
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6S5Q
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![BU of 6s5q by Molmil](/molmil-images/mine/6s5q) | Strictosidine Synthase from Ophiorrhiza pumila in complex with (S)-1-isobutyl-2,3,4,9-tetrahydro-1H-beta-carboline | 分子名称: | (1~{S})-1-(2-methylpropyl)-2,3,4,9-tetrahydro-1~{H}-pyrido[3,4-b]indole, Strictosidine synthase | 著者 | Eger, E, Sharma, M, Kroutil, W, Grogan, G. | 登録日 | 2019-07-02 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions. J.Am.Chem.Soc., 142, 2020
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6IZ6
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![BU of 6iz6 by Molmil](/molmil-images/mine/6iz6) | Crystal Structure Analysis of TRIC counter-ion channels in calcium release | 分子名称: | CALCIUM ION, Trimeric intracellular cation channel type B-B | 著者 | Liu, X.L, Wang, X.H, Su, M, Hendrickson, W.A, Chen, Y.H. | 登録日 | 2018-12-18 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.293 Å) | 主引用文献 | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
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3NU8
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4MNB
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![BU of 4mnb by Molmil](/molmil-images/mine/4mnb) | Crystal Structure of a complex between the marine anticancer drug Variolin B and DNA | 分子名称: | 5'-D(*CP*GP*TP*AP*CP*G)-3', 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol, COBALT (II) ION, ... | 著者 | Canals, A, Arribas-Bosacoma, R, Alvarez, M, Albericio, F, Aymami, J, Coll, M. | 登録日 | 2013-09-10 | 公開日 | 2015-03-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Intercalative DNA binding of the marine anticancer drug variolin B. Sci Rep, 7, 2017
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