4PWK
| Crystal structure of V30M mutant human transthyretin complexed with dihydroguaiaretic acid | 分子名称: | 4,4'-[(2R,3R)-2,3-dimethylbutane-1,4-diyl]bis(2-methoxyphenol), Transthyretin | 著者 | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | 登録日 | 2014-03-20 | 公開日 | 2014-11-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin J.Med.Chem., 57, 2014
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8W42
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8W44
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8W46
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8W48
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8W43
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8W45
| X-ray crystal structure of V30M-TTR in complex with pinostilbene | 分子名称: | 3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxy-phenol, SODIUM ION, Transthyretin | 著者 | Yokoyama, T. | 登録日 | 2023-08-23 | 公開日 | 2023-11-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin. J.Med.Chem., 66, 2023
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8W47
| X-ray crystal structure of V30M-TTR in complex with isorhapontigenin | 分子名称: | 5-[(~{E})-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]benzene-1,3-diol, SODIUM ION, Transthyretin | 著者 | Yokoyama, T. | 登録日 | 2023-08-23 | 公開日 | 2023-11-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin. J.Med.Chem., 66, 2023
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1ETA
| THE X-RAY CRYSTAL STRUCTURE REFINEMENTS OF NORMAL HUMAN TRANSTHYRETIN AND THE AMYLOIDOGENIC VAL 30-->MET VARIANT TO 1.7 ANGSTROMS RESOLUTION | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, TRANSTHYRETIN | 著者 | Braden, B.C, Steinrauf, L.K, Hamilton, J.A. | 登録日 | 1993-05-12 | 公開日 | 1995-01-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The x-ray crystal structure refinements of normal human transthyretin and the amyloidogenic Val-30-->Met variant to 1.7-A resolution. J.Biol.Chem., 268, 1993
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1FHN
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1FH2
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1MA9
| Crystal structure of the complex of human vitamin D binding protein and rabbit muscle actin | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Alpha Skeletal Muscle, ... | 著者 | Verboven, C, Bogaerts, I, Waelkens, E, Rabijns, A, Van Baelen, H, Bouillon, R, De Ranter, C. | 登録日 | 2002-08-02 | 公開日 | 2003-02-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Actin-DBP: the perfect structural fit? Acta Crystallogr.,Sect.D, 59, 2003
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2MOV
| Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal Derived AGEs. | 分子名称: | Advanced glycosylation end product-specific receptor, N~5~-[(5R)-5-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl]-L-ornithine | 著者 | Shekhtman, A, Xue, J, Ray, R, Singer, D, Bohme, D, Burz, D.S, Rai, V, Hoffman, R. | 登録日 | 2014-05-05 | 公開日 | 2014-06-25 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs. Biochemistry, 53, 2014
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2WQA
| Complex of TTR and RBP4 and Oleic Acid | 分子名称: | OLEIC ACID, RETINOL-BINDING PROTEIN 4, SULFATE ION, ... | 著者 | Nanao, M, Mercer, D, Nguyen, L, Buckley, D, Stout, T.J. | 登録日 | 2009-08-14 | 公開日 | 2010-09-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal Structure of Rbp4 Bound to Linoleic Acid and Ttr To be Published
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2D3I
| Crystal Structure of Aluminum-Bound Ovotransferrin at 2.15 Angstrom Resolution | 分子名称: | ALUMINUM ION, BICARBONATE ION, Ovotransferrin | 著者 | Mizutani, K, Mikami, B, Aibara, S, Hirose, M. | 登録日 | 2005-09-28 | 公開日 | 2005-11-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure of aluminium-bound ovotransferrin at 2.15 Angstroms resolution. Acta Crystallogr.,Sect.D, 61, 2005
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1IE4
| RAT TRANSTHYRETIN COMPLEX WITH THYROXINE (T4) | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, TRANSTHYRETIN | 著者 | Wojtczak, A. | 登録日 | 2001-04-06 | 公開日 | 2002-04-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of rat transthyretin (rTTR) complex with thyroxine at 2.5 A resolution: first non-biased insight into thyroxine binding reveals different hormone orientation in two binding sites. Acta Crystallogr.,Sect.D, 57, 2001
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8I00
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8I0O
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4PMF
| Human transthyretin (TTR) complexed with curcumin | 分子名称: | (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one, 1,2-ETHANEDIOL, SODIUM ION, ... | 著者 | Stura, E.A, Ciccone, L. | 登録日 | 2014-05-21 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Transthyretin complexes with curcumin and bromo-estradiol: evaluation of solubilizing multicomponent mixtures. N Biotechnol, 32, 2014
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4PVM
| Neutron structure of human transthyretin (TTR) at room temperature to 2.0A resolution (Laue) | 分子名称: | Transthyretin | 著者 | Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T. | 登録日 | 2014-03-18 | 公開日 | 2014-11-12 | 最終更新日 | 2024-03-20 | 実験手法 | NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION | 主引用文献 | Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein IUCrJ, 1, 2014
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4PVL
| X-ray structure of human transthyretin (TTR) at room temperature to 1.9A resolution | 分子名称: | Transthyretin | 著者 | Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T. | 登録日 | 2014-03-18 | 公開日 | 2014-11-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | 主引用文献 | Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein IUCrJ, 1, 2014
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4PVN
| Neutron structure of human transthyretin (TTR) at room temperature to 2.3A resolution (monochromatic) | 分子名称: | Transthyretin | 著者 | Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T. | 登録日 | 2014-03-18 | 公開日 | 2014-11-12 | 最終更新日 | 2024-03-20 | 実験手法 | NEUTRON DIFFRACTION (2.3 Å), X-RAY DIFFRACTION | 主引用文献 | Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein IUCrJ, 1, 2014
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1RVS
| STRUCTURE OF TRANSTHYRETIN IN AMYLOID FIBRILS DETERMINED BY SOLID-STATE MAGIC ANGLE SPINNING NMR | 分子名称: | Transthyretin | 著者 | Jaroniec, C.P, Macphee, C.E, Bajaj, V.S, Mcmahon, M.T, Dobson, C.M, Griffin, R.G. | 登録日 | 2003-12-14 | 公開日 | 2004-01-20 | 最終更新日 | 2024-05-01 | 実験手法 | SOLID-STATE NMR | 主引用文献 | High-resolution molecular structure of a peptide in an amyloid fibril determined by magic angle spinning NMR spectroscopy Proc.Natl.Acad.Sci.USA, 101, 2004
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1JL4
| CRYSTAL STRUCTURE OF THE HUMAN CD4 N-TERMINAL TWO DOMAIN FRAGMENT COMPLEXED TO A CLASS II MHC MOLECULE | 分子名称: | H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-K ALPHA CHAIN, A-K BETA CHAIN, ... | 著者 | Wang, J.-H, Meijers, R, Reinherz, E.L. | 登録日 | 2001-07-15 | 公開日 | 2001-09-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule. Proc.Natl.Acad.Sci.USA, 98, 2001
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