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4PWK
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BU of 4pwk by Molmil
Crystal structure of V30M mutant human transthyretin complexed with dihydroguaiaretic acid
分子名称: 4,4'-[(2R,3R)-2,3-dimethylbutane-1,4-diyl]bis(2-methoxyphenol), Transthyretin
著者Yokoyama, T, Kosaka, Y, Mizuguchi, M.
登録日2014-03-20
公開日2014-11-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
8W42
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BU of 8w42 by Molmil
X-ray crystal structure of V30M-TTR in complex with resveratrol
分子名称: RESVERATROL, SODIUM ION, Transthyretin
著者Yokoyama, T.
登録日2023-08-23
公開日2023-11-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
J.Med.Chem., 66, 2023
8W44
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BU of 8w44 by Molmil
X-ray crystal structure of V30M-TTR in complex with oxyresveratrol
分子名称: SODIUM ION, Transthyretin, trans-oxyresveratrol
著者Yokoyama, T.
登録日2023-08-23
公開日2023-11-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.399 Å)
主引用文献Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
J.Med.Chem., 66, 2023
8W46
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BU of 8w46 by Molmil
X-ray crystal structure of V30M-TTR in complex with pterostilbene
分子名称: Pterostilbene, SODIUM ION, Transthyretin
著者Yokoyama, T.
登録日2023-08-23
公開日2023-11-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
J.Med.Chem., 66, 2023
8W48
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BU of 8w48 by Molmil
Neutron and X-ray joint structure of WT-TTR in complex with piceatannol
分子名称: PICEATANNOL, Transthyretin
著者Yokoyama, T, Kusaka, K, Fujiwara, S.
登録日2023-08-23
公開日2023-11-22
最終更新日2023-12-06
実験手法NEUTRON DIFFRACTION (1.19 Å), X-RAY DIFFRACTION
主引用文献Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
J.Med.Chem., 66, 2023
8W43
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X-ray crystal structure of V30M-TTR in complex with piceatannol
分子名称: PICEATANNOL, SODIUM ION, Transthyretin
著者Yokoyama, T.
登録日2023-08-23
公開日2023-11-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.302 Å)
主引用文献Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
J.Med.Chem., 66, 2023
8W45
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BU of 8w45 by Molmil
X-ray crystal structure of V30M-TTR in complex with pinostilbene
分子名称: 3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxy-phenol, SODIUM ION, Transthyretin
著者Yokoyama, T.
登録日2023-08-23
公開日2023-11-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
J.Med.Chem., 66, 2023
8W47
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BU of 8w47 by Molmil
X-ray crystal structure of V30M-TTR in complex with isorhapontigenin
分子名称: 5-[(~{E})-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]benzene-1,3-diol, SODIUM ION, Transthyretin
著者Yokoyama, T.
登録日2023-08-23
公開日2023-11-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.
J.Med.Chem., 66, 2023
1ETA
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BU of 1eta by Molmil
THE X-RAY CRYSTAL STRUCTURE REFINEMENTS OF NORMAL HUMAN TRANSTHYRETIN AND THE AMYLOIDOGENIC VAL 30-->MET VARIANT TO 1.7 ANGSTROMS RESOLUTION
分子名称: 3,5,3',5'-TETRAIODO-L-THYRONINE, TRANSTHYRETIN
著者Braden, B.C, Steinrauf, L.K, Hamilton, J.A.
登録日1993-05-12
公開日1995-01-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The x-ray crystal structure refinements of normal human transthyretin and the amyloidogenic Val-30-->Met variant to 1.7-A resolution.
J.Biol.Chem., 268, 1993
1FHN
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BU of 1fhn by Molmil
TRANSTHYRETIN STABILITY AS A KEY FACTOR IN AMYLOIDOGENESIS
分子名称: Transthyretin
著者Sebastiao, M.P.
登録日2000-08-02
公開日2001-07-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Transthyretin stability as a key factor in amyloidogenesis: X-ray analysis at atomic resolution.
J.Mol.Biol., 306, 2001
1FH2
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TRANSTHYRETIN STABILITY AS A KEY FACTOR IN AMYLOIDOGENESIS
分子名称: TRANSTHYRETIN
著者Sebastiao, M.P.
登録日2000-07-31
公開日2001-07-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Transthyretin stability as a key factor in amyloidogenesis: X-ray analysis at atomic resolution.
J.Mol.Biol., 306, 2001
1MA9
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BU of 1ma9 by Molmil
Crystal structure of the complex of human vitamin D binding protein and rabbit muscle actin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Alpha Skeletal Muscle, ...
著者Verboven, C, Bogaerts, I, Waelkens, E, Rabijns, A, Van Baelen, H, Bouillon, R, De Ranter, C.
登録日2002-08-02
公開日2003-02-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Actin-DBP: the perfect structural fit?
Acta Crystallogr.,Sect.D, 59, 2003
2MOV
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BU of 2mov by Molmil
Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal Derived AGEs.
分子名称: Advanced glycosylation end product-specific receptor, N~5~-[(5R)-5-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl]-L-ornithine
著者Shekhtman, A, Xue, J, Ray, R, Singer, D, Bohme, D, Burz, D.S, Rai, V, Hoffman, R.
登録日2014-05-05
公開日2014-06-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs.
Biochemistry, 53, 2014
2WQA
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BU of 2wqa by Molmil
Complex of TTR and RBP4 and Oleic Acid
分子名称: OLEIC ACID, RETINOL-BINDING PROTEIN 4, SULFATE ION, ...
著者Nanao, M, Mercer, D, Nguyen, L, Buckley, D, Stout, T.J.
登録日2009-08-14
公開日2010-09-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal Structure of Rbp4 Bound to Linoleic Acid and Ttr
To be Published
2D3I
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BU of 2d3i by Molmil
Crystal Structure of Aluminum-Bound Ovotransferrin at 2.15 Angstrom Resolution
分子名称: ALUMINUM ION, BICARBONATE ION, Ovotransferrin
著者Mizutani, K, Mikami, B, Aibara, S, Hirose, M.
登録日2005-09-28
公開日2005-11-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of aluminium-bound ovotransferrin at 2.15 Angstroms resolution.
Acta Crystallogr.,Sect.D, 61, 2005
1IE4
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BU of 1ie4 by Molmil
RAT TRANSTHYRETIN COMPLEX WITH THYROXINE (T4)
分子名称: 3,5,3',5'-TETRAIODO-L-THYRONINE, TRANSTHYRETIN
著者Wojtczak, A.
登録日2001-04-06
公開日2002-04-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of rat transthyretin (rTTR) complex with thyroxine at 2.5 A resolution: first non-biased insight into thyroxine binding reveals different hormone orientation in two binding sites.
Acta Crystallogr.,Sect.D, 57, 2001
8I00
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BU of 8i00 by Molmil
Crystal structure of A97S transthyretin
分子名称: Transthyretin
著者Agrawal, S, Yu, T.-Y.
登録日2023-01-10
公開日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and dynamics of pathogenic transthyretin variant A97S
To Be Published
8I0O
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BU of 8i0o by Molmil
Crystal structure of Transthyretin variant A97S in monomeric form
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Transthyretin
著者Agrawal, S, Yu, T.-Y.
登録日2023-01-11
公開日2024-01-17
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structure and dynamics of Transthyretin pathogenic variant A97S
To Be Published
4PMF
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BU of 4pmf by Molmil
Human transthyretin (TTR) complexed with curcumin
分子名称: (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one, 1,2-ETHANEDIOL, SODIUM ION, ...
著者Stura, E.A, Ciccone, L.
登録日2014-05-21
公開日2014-10-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Transthyretin complexes with curcumin and bromo-estradiol: evaluation of solubilizing multicomponent mixtures.
N Biotechnol, 32, 2014
4PVM
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BU of 4pvm by Molmil
Neutron structure of human transthyretin (TTR) at room temperature to 2.0A resolution (Laue)
分子名称: Transthyretin
著者Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T.
登録日2014-03-18
公開日2014-11-12
最終更新日2024-03-20
実験手法NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION
主引用文献Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein
IUCrJ, 1, 2014
4PVL
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BU of 4pvl by Molmil
X-ray structure of human transthyretin (TTR) at room temperature to 1.9A resolution
分子名称: Transthyretin
著者Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T.
登録日2014-03-18
公開日2014-11-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein
IUCrJ, 1, 2014
4PVN
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BU of 4pvn by Molmil
Neutron structure of human transthyretin (TTR) at room temperature to 2.3A resolution (monochromatic)
分子名称: Transthyretin
著者Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T.
登録日2014-03-18
公開日2014-11-12
最終更新日2024-03-20
実験手法NEUTRON DIFFRACTION (2.3 Å), X-RAY DIFFRACTION
主引用文献Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein
IUCrJ, 1, 2014
1RVS
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BU of 1rvs by Molmil
STRUCTURE OF TRANSTHYRETIN IN AMYLOID FIBRILS DETERMINED BY SOLID-STATE MAGIC ANGLE SPINNING NMR
分子名称: Transthyretin
著者Jaroniec, C.P, Macphee, C.E, Bajaj, V.S, Mcmahon, M.T, Dobson, C.M, Griffin, R.G.
登録日2003-12-14
公開日2004-01-20
最終更新日2024-05-01
実験手法SOLID-STATE NMR
主引用文献High-resolution molecular structure of a peptide in an amyloid fibril determined by magic angle spinning NMR spectroscopy
Proc.Natl.Acad.Sci.USA, 101, 2004
1JL4
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BU of 1jl4 by Molmil
CRYSTAL STRUCTURE OF THE HUMAN CD4 N-TERMINAL TWO DOMAIN FRAGMENT COMPLEXED TO A CLASS II MHC MOLECULE
分子名称: H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-K ALPHA CHAIN, A-K BETA CHAIN, ...
著者Wang, J.-H, Meijers, R, Reinherz, E.L.
登録日2001-07-15
公開日2001-09-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule.
Proc.Natl.Acad.Sci.USA, 98, 2001

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