8W42

X-ray crystal structure of V30M-TTR in complex with resveratrol

Summary for 8W42

Entry DOI	10.2210/pdb8w42/pdb
Descriptor	Transthyretin, RESVERATROL, SODIUM ION, ... (4 entities in total)
Functional Keywords	amyloidogenesis, thyroid hormone inhibitor, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	35164.64
Authors	Yokoyama, T. (deposition date: 2023-08-23, release date: 2023-11-22, Last modification date: 2023-12-06)
Primary citation	Yokoyama, T.,Kusaka, K.,Mizuguchi, M.,Nabeshima, Y.,Fujiwara, S. Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin. J.Med.Chem., 66:15511-15523, 2023 Cited by PubMed: 37910439 DOI: 10.1021/acs.jmedchem.3c01698 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation