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6S1N
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Human polymerase delta holoenzyme Conformer 2
分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
著者Lancey, C, Hamdan, S.M, De Biasio, A.
登録日2019-06-19
公開日2019-12-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.86 Å)
主引用文献Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
7OYD
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BU of 7oyd by Molmil
Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
著者Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A.
登録日2021-06-24
公開日2022-07-20
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献A molecular network of conserved factors keeps ribosomes dormant in the egg.
Nature, 613, 2023
2J0Q
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BU of 2j0q by Molmil
The crystal structure of the Exon Junction Complex at 3.2 A resolution
分子名称: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ...
著者Bono, F, Ebert, J, Lorentzen, E, Conti, E.
登録日2006-08-04
公開日2006-08-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on Mrna.
Cell(Cambridge,Mass.), 126, 2006
6S1O
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BU of 6s1o by Molmil
Human polymerase delta holoenzyme Conformer 3
分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
著者Lancey, C, Hamdan, S.M, De Biasio, A.
登録日2019-06-19
公開日2019-12-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
7PY2
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BU of 7py2 by Molmil
Structure of pathological TDP-43 filaments from ALS with FTLD
分子名称: TAR DNA-binding protein 43
著者Arseni, D, Hasegawa, H, Murzin, A.G, Kametani, F, Arai, M, Yoshida, M, Falcon, B.
登録日2021-10-08
公開日2021-12-15
最終更新日2022-01-19
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structure of pathological TDP-43 filaments from ALS with FTLD.
Nature, 601, 2022
7UV9
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BU of 7uv9 by Molmil
KDM2A-nucleosome structure stabilized by H3K36C-UNC8015 covalent conjugate
分子名称: DNA (185-MER), FE (III) ION, Histone H2A type 1, ...
著者Spangler, C.J, Skrajna, A, Foley, C.A, Budziszewski, G.R, Azzam, D.N, James, L.I, Frye, S.V, McGinty, R.K.
登録日2022-04-29
公開日2023-02-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of paralog-specific KDM2A/B nucleosome recognition.
Nat.Chem.Biol., 19, 2023
1NH3
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BU of 1nh3 by Molmil
Human Topoisomerase I Ara-C Complex
分子名称: 5'-D(*(GNG)P*GP*AP*AP*AP*AP*AP*UP*UP*UP*UP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*UP*(UBB))-3', 5'-D(*AP*AP*AP*AP*AP*TP*UP*UP*UP*UP*CP*(CAR)P*AP*AP*GP*UP*CP*UP*UP*UP*UP*T)-3', ...
著者Chrencik, J.E, Burgin, A.B, Pommier, Y, Stewart, L, Redinbo, M.R.
登録日2002-12-18
公開日2003-03-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Impact of the Leukemia Drug 1-beta-D-Arabinofuranosylcytosine (Ara-C) on the Covalent Human Topoisomerase I-DNA Complex
J.Biol.Chem., 278, 2003
7WTW
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BU of 7wtw by Molmil
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3
分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R.
登録日2022-02-05
公開日2022-10-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The nucleoplasmic phase of pre-40S formation prior to nuclear export.
Nucleic Acids Res., 50, 2022
7WTT
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BU of 7wtt by Molmil
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1)
分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R.
登録日2022-02-05
公開日2022-10-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The nucleoplasmic phase of pre-40S formation prior to nuclear export.
Nucleic Acids Res., 50, 2022
7WTU
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BU of 7wtu by Molmil
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (without CK1)
分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R.
登録日2022-02-05
公開日2022-10-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The nucleoplasmic phase of pre-40S formation prior to nuclear export.
Nucleic Acids Res., 50, 2022
7TUT
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BU of 7tut by Molmil
Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the multipass translocon
分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S.
登録日2022-02-03
公開日2022-10-19
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献Mechanism of an intramembrane chaperone for multipass membrane proteins.
Nature, 611, 2022
6SE6
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BU of 6se6 by Molmil
Class2 : CENP-A nucleosome in complex with CENP-C central region
分子名称: Centromere protein C, DNA (145-MER), Histone H2A type 2-A, ...
著者Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N.
登録日2019-07-29
公開日2019-08-14
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
Embo Rep., 20, 2019
6SEE
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BU of 6see by Molmil
Class2A : CENP-A nucleosome in complex with CENP-C central region
分子名称: Centromere protein C, DNA (145-MER), Histone H2A type 2-A, ...
著者Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N.
登録日2019-07-29
公開日2019-08-14
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
Embo Rep., 20, 2019
6SEF
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BU of 6sef by Molmil
Class2C : CENP-A nucleosome in complex with CENP-C central region
分子名称: Centromere protein C, DNA (145-MER), Histone H2A type 2-A, ...
著者Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N.
登録日2019-07-29
公開日2019-08-14
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
Embo Rep., 20, 2019
1PO6
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BU of 1po6 by Molmil
Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
分子名称: 5'-D(*T*AP*GP*GP*(6MI)P*TP*TP*AP*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
著者Myers, J.C, Moore, S.A, Shamoo, Y.
登録日2003-06-13
公開日2003-11-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
J.BIOL.CHEM., 278, 2003
6R8Z
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BU of 6r8z by Molmil
Cryo-EM structure of NCP_THF2(-1)-UV-DDB
分子名称: DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ...
著者Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H.
登録日2019-04-02
公開日2019-06-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
6R6G
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BU of 6r6g by Molmil
Structure of XBP1u-paused ribosome nascent chain complex with SRP.
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
著者Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R.
登録日2019-03-27
公開日2019-07-10
最終更新日2019-10-30
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8, 2019
6R92
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BU of 6r92 by Molmil
Cryo-EM structure of NCP-THF2(+1)-UV-DDB class B
分子名称: DNA damage-binding protein 1,DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ...
著者Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H.
登録日2019-04-02
公開日2019-06-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
1PKM
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BU of 1pkm by Molmil
THE REFINED THREE-DIMENSIONAL STRUCTURE OF CAT MUSCLE (M1) PYRUVATE KINASE, AT A RESOLUTION OF 2.6 ANGSTROMS
分子名称: M1 PYRUVATE KINASE
著者Allen, S.C, Muirhead, H.
登録日1995-07-13
公開日1995-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Refined three-dimensional structure of cat-muscle (M1) pyruvate kinase at a resolution of 2.6 A.
Acta Crystallogr.,Sect.D, 52, 1996
6SYF
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BU of 6syf by Molmil
Human Ubc9 with covalent isopeptide ligand
分子名称: ACE-ILE-LYS-GLN-GLU, ACE-LEU-ARG-LEU-ARG-GLY-CYS, SUMO-conjugating enzyme UBC9
著者Hofmann, R, Akimoto, G, Wucherpfennig, T.G, Zeymer, C, Bode, J.W.
登録日2019-09-27
公開日2020-08-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins.
Nat.Chem., 12, 2020
6R5Q
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BU of 6r5q by Molmil
Structure of XBP1u-paused ribosome nascent chain complex (post-state)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
著者Shanmuganathan, V, Cheng, J, Berninghausen, O, Beckmann, R.
登録日2019-03-25
公開日2019-07-10
最終更新日2019-10-30
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8, 2019
2GRR
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BU of 2grr by Molmil
Crystal Structure of human RanGAP1-Ubc9-D127S
分子名称: Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I
著者Yunus, A.A, Lima, C.D.
登録日2006-04-24
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
7V9A
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BU of 7v9a by Molmil
biogenesis module of human telomerase holoenzyme
分子名称: H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ...
著者Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M.
登録日2021-08-24
公開日2022-03-30
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.94 Å)
主引用文献Zipper head mechanism of telomere synthesis by human telomerase.
Cell Res., 31, 2021
6S1M
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BU of 6s1m by Molmil
Human polymerase delta holoenzyme Conformer 1
分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
著者Lancey, C, Hamdan, S.M, De Biasio, A.
登録日2019-06-19
公開日2019-12-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.27 Å)
主引用文献Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
1PKN
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BU of 1pkn by Molmil
STRUCTURE OF RABBIT MUSCLE PYRUVATE KINASE COMPLEXED WITH MN2+, K+, AND PYRUVATE
分子名称: MANGANESE (II) ION, POTASSIUM ION, PYRUVATE KINASE, ...
著者Larsen, T.M, Laughlin, L.T, Holden, H.M, Rayment, I, Reed, G.H.
登録日1994-03-25
公開日1995-01-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of rabbit muscle pyruvate kinase complexed with Mn2+, K+, and pyruvate.
Biochemistry, 33, 1994

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