7ZT6
 
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7ZWA
 | | CryoEM structure of Ku heterodimer bound to DNA and PAXX | | 分子名称: | DNA (5'-D(P*CP*GP*AP*TP*AP*TP*CP*TP*AP*GP*AP*GP*GP*GP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*CP*TP*CP*TP*AP*GP*AP*TP*AP*T)-3'), PHOSPHATE ION, ... | | 著者 | Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K. | | 登録日 | 2022-05-19 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
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7ZYG
 | | CryoEM structure of Ku heterodimer bound to DNA, PAXX and XLF | | 分子名称: | DNA, Non-homologous end-joining factor 1, PHOSPHATE ION, ... | | 著者 | Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K. | | 登録日 | 2022-05-24 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
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3A4S
 | | The crystal structure of the SLD2:Ubc9 complex | | 分子名称: | NFATC2-interacting protein, SUMO-conjugating enzyme UBC9 | | 著者 | Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M. | | 登録日 | 2009-07-14 | | 公開日 | 2010-02-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45
Proteins, 78, 2009
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8AG5
 | | Vaccinia C16 protein bound to Ku70/Ku80 | | 分子名称: | Ku70-Xrcc6, Protein C10, X-ray repair cross-complementing protein 5 | | 著者 | Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O. | | 登録日 | 2022-07-19 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
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8AG4
 | | Vaccinia C16 protein bound to Ku70/Ku80 | | 分子名称: | Protein C10, X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6 | | 著者 | Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O. | | 登録日 | 2022-07-19 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (2.46 Å) | | 主引用文献 | Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
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8BOT
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8BPO
 | | Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER) | | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Hopfler, M, Absmeier, E, Passmore, L.A, Hegde, R.S. | | 登録日 | 2022-11-17 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation.
Mol.Cell, 83, 2023
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2XWU
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8BHV
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8BHF
 | | Cryo-EM structure of stalled rabbit 80S ribosomes in complex with human CCR4-NOT and CNOT4 | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S11, ... | | 著者 | Absmeier, E, Chandrasekaran, V, O'Reilly, F.J, Stowell, J.A.W, Rappsilber, J, Passmore, L.A. | | 登録日 | 2022-10-31 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
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3AN2
 | | The structure of the centromeric nucleosome containing CENP-A | | 分子名称: | 147 mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Tachiwana, H, Kagawa, W, Shiga, T, Saito, K, Osakabe, A, Hayashi-Takanaka, Y, Park, S.-Y, Kimura, H, Kurumizaka, H. | | 登録日 | 2010-08-27 | | 公開日 | 2011-07-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Crystal structure of the human centromeric nucleosome containing CENP-A
Nature, 476, 2011
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1A3S
 | | HUMAN UBC9 | | 分子名称: | UBC9 | | 著者 | Naismith, J.H, Giraud, M. | | 登録日 | 1998-01-23 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of ubiquitin-conjugating enzyme 9 displays significant differences with other ubiquitin-conjugating enzymes which may reflect its specificity for sumo rather than ubiquitin.
Acta Crystallogr.,Sect.D, 54, 1998
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5EN1
 | | Crystal structure of hnRNPA2B1 in complex with RNA | | 分子名称: | Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*AP*CP*UP*G)-3') | | 著者 | Wu, B.X, Su, S.C, Ma, J.B. | | 登録日 | 2015-11-09 | | 公開日 | 2016-11-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1
Nat Commun, 2018
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4RPP
 | | crystal structure of PKM2-K422R mutant bound with FBP | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, Pyruvate kinase PKM | | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | | 登録日 | 2014-10-31 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.585 Å) | | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2.
Protein Cell, 6, 2015
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7OYD
 | | Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | | 登録日 | 2021-06-24 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | A molecular network of conserved factors keeps ribosomes dormant in the egg.
Nature, 613, 2023
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3EX7
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7PY2
 | | Structure of pathological TDP-43 filaments from ALS with FTLD | | 分子名称: | TAR DNA-binding protein 43 | | 著者 | Arseni, D, Hasegawa, H, Murzin, A.G, Kametani, F, Arai, M, Yoshida, M, Falcon, B. | | 登録日 | 2021-10-08 | | 公開日 | 2021-12-15 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structure of pathological TDP-43 filaments from ALS with FTLD.
Nature, 601, 2022
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4BS2
 | | NMR structure of human TDP-43 tandem RRMs in complex with UG-rich RNA | | 分子名称: | 5'-R(*GP*UP*GP*UP*GP*AP*AP*UP*GP*AP*AP*UP)-3', TAR DNA-BINDING PROTEIN 43 | | 著者 | Lukavsky, P.J, Daujotyte, D, Tollervey, J.R, Ule, J, Stuani, C, Buratti, E, Baralle, F.E, Damberger, F.F, Allain, F.H.T. | | 登録日 | 2013-06-06 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular Basis of Ug-Rich RNA Recognition by the Human Splicing Factor Tdp-43
Nat.Struct.Mol.Biol., 20, 2013
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4D5L
 | | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | | 分子名称: | 18S RRNA 2, 40S RIBOSOMAL PROTEIN ES1, 40S RIBOSOMAL PROTEIN ES10, ... | | 著者 | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | | 登録日 | 2014-11-05 | | 公開日 | 2015-02-04 | | 最終更新日 | 2017-08-23 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
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7R4X
 | | Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J. | | 登録日 | 2022-02-09 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | | 主引用文献 | Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution.
Nucleic Acids Res., 51, 2023
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7SGL
 | | DNA-PK complex of DNA end processing | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA-dependent protein kinase catalytic subunit, Hairpin_1, ... | | 著者 | Liu, L, Li, J, Chen, X, Yang, W, Gellert, M. | | 登録日 | 2021-10-06 | | 公開日 | 2022-01-12 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Autophosphorylation transforms DNA-PK from protecting to processing DNA ends.
Mol.Cell, 82, 2022
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4C9B
 | | Crystal structure of eIF4AIII-CWC22 complex | | 分子名称: | EUKARYOTIC INITIATION FACTOR 4A-III, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Buchwald, G, Schuessler, S, Basquin, C, LeHir, H, Conti, E. | | 登録日 | 2013-10-02 | | 公開日 | 2013-11-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of the Human Eif4Aiii-Cwc22 Complex Shows How a Dead-Box Protein is Inhibited by a Mif4G Domain
Proc.Natl.Acad.Sci.USA, 110, 2013
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6L49
 | | H3-CA-H3 tri-nucleosome with the 22 base-pair linker DNA | | 分子名称: | DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H. | | 登録日 | 2019-10-16 | | 公開日 | 2019-12-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (18.9 Å) | | 主引用文献 | Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.
Structure, 28, 2020
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6KXV
 | | Crystal structure of a nucleosome containing Leishmania histone H3 | | 分子名称: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Dacher, M, Taguchi, H, Kujirai, T, Kurumizaka, H. | | 登録日 | 2019-09-13 | | 公開日 | 2020-07-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.63 Å) | | 主引用文献 | Incorporation and influence of Leishmania histone H3 in chromatin.
Nucleic Acids Res., 47, 2019
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