6SYF

Human Ubc9 with covalent isopeptide ligand

Summary for 6SYF

Entry DOI	10.2210/pdb6syf/pdb
Descriptor	SUMO-conjugating enzyme UBC9, ACE-LEU-ARG-LEU-ARG-GLY-CYS, ACE-ILE-LYS-GLN-GLU, ... (4 entities in total)
Functional Keywords	ubc9, isopeptide, disulfide, ubiquitin, sumo, ligase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	12
Total formula weight	76155.79
Authors	Hofmann, R.,Akimoto, G.,Wucherpfennig, T.G.,Zeymer, C.,Bode, J.W. (deposition date: 2019-09-27, release date: 2020-08-12, Last modification date: 2024-01-24)
Primary citation	Hofmann, R.,Akimoto, G.,Wucherpfennig, T.G.,Zeymer, C.,Bode, J.W. Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins. Nat.Chem., 12:1008-1015, 2020 Cited by PubMed: 32929246 DOI: 10.1038/s41557-020-0528-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation