7CR0
| human KCNQ2 in apo state | 分子名称: | Potassium voltage-gated channel subfamily KQT member 2 | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CR3
| human KCNQ2-CaM in apo state | 分子名称: | Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 2 | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CR4
| human KCNQ2-CaM in complex with ztz240 | 分子名称: | Calmodulin-3, N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7E7Z
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7E83
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7E87
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7E84
| CryoEM structure of human Kv4.2-KChIP1 complex | 分子名称: | Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2 | 著者 | Kise, Y, Nureki, O. | 登録日 | 2021-02-28 | 公開日 | 2021-10-13 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
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7E8E
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7DXF
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7DXC
| Structure of TRPC3 at 3.06 angstrom in low calcium state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL HEMISUCCINATE, Short transient receptor potential channel 3, ... | 著者 | Chen, L, Guo, W. | 登録日 | 2021-01-18 | 公開日 | 2022-02-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites. Neuron, 110, 2022
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7DXG
| Structure of SAR7334-bound TRPC6 at 2.9 angstrom | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[[(1R,2R)-2-[(3R)-3-azanylpiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloranyl-benzenecarbonitrile, CALCIUM ION, ... | 著者 | Chen, L, Guo, W. | 登録日 | 2021-01-18 | 公開日 | 2022-02-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites. Neuron, 110, 2022
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7DXE
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7DXB
| Structure of TRPC3 at 2.7 angstrom in high calcium state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Chen, L, Guo, W. | 登録日 | 2021-01-18 | 公開日 | 2022-02-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites. Neuron, 110, 2022
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7DTC
| voltage-gated sodium channel Nav1.5-E1784K | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein type 5 subunit alpha | 著者 | Yan, N, Pan, X, Li, Z. | 登録日 | 2021-01-04 | 公開日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of human Na v 1.5 reveals the fast inactivation-related segments as a mutational hotspot for the long QT syndrome. Proc.Natl.Acad.Sci.USA, 118, 2021
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7DTD
| Voltage-gated sodium channel Nav1.1 and beta4 | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein type 1 subunit alpha, ... | 著者 | Yan, N, Pan, X, Li, Z, Huang, G. | 登録日 | 2021-01-04 | 公開日 | 2021-04-07 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Comparative structural analysis of human Na v 1.1 and Na v 1.5 reveals mutational hotspots for sodium channelopathies. Proc.Natl.Acad.Sci.USA, 118, 2021
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7DXD
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7FHN
| Structure of AtTPC1 D240A/D454A/E528A mutant with 1 mM Ca2+ | 分子名称: | CALCIUM ION, Two pore calcium channel protein 1,GFP | 著者 | Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J. | 登録日 | 2021-07-29 | 公開日 | 2021-12-01 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1. Proc.Natl.Acad.Sci.USA, 118, 2021
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7FHO
| Structure of AtTPC1 D240A/D454A/E528A mutant with 50 mM Ca2+ | 分子名称: | CALCIUM ION, Two pore calcium channel protein 1,GFP | 著者 | Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J. | 登録日 | 2021-07-29 | 公開日 | 2021-12-01 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1. Proc.Natl.Acad.Sci.USA, 118, 2021
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7FHL
| Structure of AtTPC1 with 50 mM Ca2+ | 分子名称: | AtTPC1-Cter, CALCIUM ION, Two pore calcium channel protein 1,GFP | 著者 | Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J. | 登録日 | 2021-07-29 | 公開日 | 2021-12-01 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1. Proc.Natl.Acad.Sci.USA, 118, 2021
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7FHK
| Structure of AtTPC1 with 1 mM Ca2+ | 分子名称: | AtTPC1-Cter, CALCIUM ION, Two pore calcium channel protein 1,GFP | 著者 | Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J. | 登録日 | 2021-07-29 | 公開日 | 2021-12-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1. Proc.Natl.Acad.Sci.USA, 118, 2021
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7FBS
| structure of a channel | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1-[2-[(2R)-2-oxidanyl-3-(propylamino)propoxy]phenyl]-3-phenyl-propan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Jiang, D.J, Catterall, W.A. | 登録日 | 2021-07-12 | 公開日 | 2021-09-22 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Open-state structure and pore gating mechanism of the cardiac sodium channel. Cell, 184, 2021
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7F0J
| CryoEM structure of human Kv4.2 | 分子名称: | Potassium voltage-gated channel subfamily D member 2, ZINC ION | 著者 | Kise, Y, Nureki, O. | 登録日 | 2021-06-04 | 公開日 | 2021-10-13 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
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7F3F
| CryoEM structure of human Kv4.2-KChIP1 complex | 分子名称: | Isoform 2 of Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2 | 著者 | Kise, Y, Nureki, O. | 登録日 | 2021-06-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
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7CR1
| human KCNQ2 in complex with ztz240 | 分子名称: | N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7D7E
| Structure of PKD1L3-CTD/PKD2L1 in apo state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Polycystic kidney disease 2-like 1 protein, ... | 著者 | Su, Q, Chen, M, Li, B, Wang, Y, Jing, D, Zhan, X, Yu, Y, Shi, Y. | 登録日 | 2020-10-03 | 公開日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for Ca 2+ activation of the heteromeric PKD1L3/PKD2L1 channel. Nat Commun, 12, 2021
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