5FSO
| MTH1 substrate recognition: Complex with a methylaminopyrimidinedione. | 分子名称: | 6-(METHYLAMINO)-1H-PYRIMIDINE-2,4-DIONE, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, ... | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | 登録日 | 2016-01-06 | 公開日 | 2017-01-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | MTH1 Substrate Recognition--An Example of Specific Promiscuity. PLoS ONE, 11, 2016
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5FSN
| MTH1 substrate recognition: Complex with a aminomethylpyrimidinyl oxypropanol. | 分子名称: | 3-(2-AMINO-6-METHYL-PYRIMIDIN-4-YL)OXYPROPAN-1-OL, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, ... | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | 登録日 | 2016-01-06 | 公開日 | 2016-07-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
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5FSM
| MTH1 substrate recognition: Complex with a methylbenzimidazolyl acetamide. | 分子名称: | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, DIMETHYL SULFOXIDE, ... | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | 登録日 | 2016-01-06 | 公開日 | 2016-07-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
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5FSL
| MTH1 substrate recognition: Complex with a methylaminopurinone | 分子名称: | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 9-METHYL-2-(METHYLAMINO)-1H-PURIN-6-ONE, SULFATE ION | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | 登録日 | 2016-01-06 | 公開日 | 2016-07-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
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5FSK
| MTH1 substrate recognition: Complex with 8-oxo-dGTP. | 分子名称: | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 8-OXO-ADENOSINE-5'-TRIPHOSPHATE, ACETATE ION | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | 登録日 | 2016-01-06 | 公開日 | 2016-07-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
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5FSI
| MTH1 substrate recognition: Complex with 8-oxo-dGTP. | 分子名称: | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | 登録日 | 2016-01-06 | 公開日 | 2016-07-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
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5DEQ
| Crystal structure of transcriptional factor AraR from Bacteroides thetaiotaomicron VPI in complex with L-arabinose | 分子名称: | FORMIC ACID, SULFATE ION, TRANSCRIPTIONAL REGULATOR AraR, ... | 著者 | Chang, C, Tesar, C, Rodionov, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-08-25 | 公開日 | 2015-10-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A novel transcriptional regulator of L-arabinose utilization in human gut bacteria. Nucleic Acids Res., 43, 2015
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5DDG
| The structure of transcriptional factor AraR from Bacteroides thetaiotaomicron VPI in complex with target double strand DNA | 分子名称: | DNA (27-MER), FORMIC ACID, MALONIC ACID, ... | 著者 | Chang, C, Tesar, C, Rodionov, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-08-24 | 公開日 | 2015-09-09 | 最終更新日 | 2015-12-16 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | A novel transcriptional regulator of L-arabinose utilization in human gut bacteria. Nucleic Acids Res., 43, 2015
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5DD4
| Apo structure of transcriptional factor AraR from Bacteroides thetaiotaomicron VPI | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, TRANSCRIPTIONAL REGULATOR AraR | 著者 | Chang, C, Tesar, C, Rodionov, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-08-24 | 公開日 | 2015-09-09 | 最終更新日 | 2015-12-16 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | A novel transcriptional regulator of L-arabinose utilization in human gut bacteria. Nucleic Acids Res., 43, 2015
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5CFJ
| Structural and functional attributes of malaria parasite Ap4A hydrolase | 分子名称: | BIS(5'-nucleosyl)-tetraphosphatase (Diadenosine tetraphosphatase), putative, DI(HYDROXYETHYL)ETHER, ... | 著者 | Sharma, A, Yogavel, M, Sharma, A. | 登録日 | 2015-07-08 | 公開日 | 2016-02-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structural and functional attributes of malaria parasite diadenosine tetraphosphate hydrolase Sci Rep, 6, 2016
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5CFI
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5C8L
| Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, NudF protein, ... | 著者 | Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M. | 登録日 | 2015-06-25 | 公開日 | 2016-01-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus. Plos One, 10, 2015
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5C7T
| Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase in complex with ADP-ribose | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5-DIPHOSPHORIBOSE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M. | 登録日 | 2015-06-24 | 公開日 | 2016-01-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus. Plos One, 10, 2015
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5C7Q
| Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M. | 登録日 | 2015-06-24 | 公開日 | 2016-01-20 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus. Plos One, 10, 2015
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5BS6
| Apo structure of transcriptional factor AraR from Bacteroides thetaiotaomicron VPI | 分子名称: | 1,2-ETHANEDIOL, transcriptional regulator AraR | 著者 | Chang, C, Tesar, C, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-06-01 | 公開日 | 2015-06-17 | 最終更新日 | 2015-12-16 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | A novel transcriptional regulator of L-arabinose utilization in human gut bacteria. Nucleic Acids Res., 43, 2015
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5BON
| Crystal structure of human Nudt15 (MTH2) | 分子名称: | MAGNESIUM ION, Probable 8-oxo-dGTP diphosphatase NUDT15 | 著者 | Carter, M, Jemth, A.-S, Helleday, T, Stenmark, P. | 登録日 | 2015-05-27 | 公開日 | 2015-08-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2. Nat Commun, 6, 2015
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5ANW
| MTH1 in complex with compound 24 | 分子名称: | 2-[4-(2-AMINOQUINAZOLIN-4-YL)PHENYL]-N,N-DIMETHYL-ACETAMIDE, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE | 著者 | Read, J.A, Breed, J. | 登録日 | 2015-09-08 | 公開日 | 2016-03-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Potent and Selective Inhibitors of Mth1 Probe its Role in Cancer Cell Survival. J.Med.Chem., 59, 2016
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5ANV
| MTH1 in complex with compound 15 | 分子名称: | 4-(4-CHLORO-2-FLUORO-ANILINO)-6,7-DIMETHOXY-N-METHYL-QUINOLINE-3-CARBOXAMIDE, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE | 著者 | Read, J.A, Breed, J. | 登録日 | 2015-09-08 | 公開日 | 2016-03-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Potent and Selective Inhibitors of Mth1 Probe its Role in Cancer Cell Survival. J.Med.Chem., 59, 2016
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5ANU
| MTH1 in complex with compound 15 | 分子名称: | 13-(METHYLAMINO)-23,24,25-TRIOXA-17,18,19,21-TETRAZATETRACYCLO-TRICOSA-1(3),2(10),4(11),12(14),13(18),16(19)-HEXAN-15-ONE, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, DIMETHYL SULFOXIDE | 著者 | Read, J.A, Breed, J. | 登録日 | 2015-09-08 | 公開日 | 2016-03-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Potent and Selective Inhibitors of Mth1 Probe its Role in Cancer Cell Survival. J.Med.Chem., 59, 2016
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5ANT
| Potent and selective inhibitors of MTH1 probe its role in cancer cell survival | 分子名称: | 2-(2-methoxyethoxy)-6-(methylamino)-9-(phenylmethyl)-7H-purin-8-one, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE | 著者 | Kettle, J.G, Alwan, H, Bista, M, Breed, J, Kack, H, Eckersley, K, Foote, K.M, Fillery, S, Goodwin, L, Jones, D, Lau, A, Nissink, J.W.M, Read, J, Scott, J, Taylor, B, Walker, G, Wissler, L. | 登録日 | 2015-09-08 | 公開日 | 2016-03-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Potent and Selective Inhibitors of Mth1 Probe its Role in Cancer Cell Survival. J.Med.Chem., 59, 2016
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5ANS
| Potent and selective inhibitors of MTH1 probe its role in cancer cell survival | 分子名称: | 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE | 著者 | Kettle, J.G, Alwan, H, Bista, M, Breed, J, Kack, H, Eckersley, K, Foote, K.M, Fillery, S, Goodwin, L, Jones, D, Lau, A, Nissink, J.W.M, Read, J, Scott, J, Taylor, B, Walker, G, Wissler, L. | 登録日 | 2015-09-08 | 公開日 | 2016-03-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Potent and Selective Inhibitors of Mth1 Probe its Role in Cancer Cell Survival. J.Med.Chem., 59, 2016
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4ZBP
| Crystal structure of the AMPCPR-bound AtNUDT7 | 分子名称: | ALPHA-BETA METHYLENE ADP-RIBOSE, Nudix hydrolase 7, SULFATE ION | 著者 | Tang, Q, Liu, C, Zhong, C, Ding, J. | 登録日 | 2015-04-15 | 公開日 | 2015-09-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structures of Arabidopsis thaliana Nudix Hydrolase NUDT7 Reveal a Previously Unobserved Conformation. Mol Plant, 8, 2015
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4ZB3
| Crystal structure of the apo AtNUDT7 | 分子名称: | Nudix hydrolase 7, SULFATE ION | 著者 | Tang, Q, Liu, C, Zhong, C, Ding, J. | 登録日 | 2015-04-14 | 公開日 | 2015-09-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of Arabidopsis thaliana Nudix Hydrolase NUDT7 Reveal a Previously Unobserved Conformation. Mol Plant, 8, 2015
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4S2Y
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4S2X
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