5FSN
MTH1 substrate recognition: Complex with a aminomethylpyrimidinyl oxypropanol.
Summary for 5FSN
| Entry DOI | 10.2210/pdb5fsn/pdb |
| Related | 5FSI 5FSK 5FSL 5FSM 5FSO |
| Descriptor | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 3-(2-AMINO-6-METHYL-PYRIMIDIN-4-YL)OXYPROPAN-1-OL, ACETATE ION, ... (5 entities in total) |
| Functional Keywords | nudt1, hydrolase |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Isoform p18: Cytoplasm. Isoform p26: Cytoplasm: P36639 |
| Total number of polymer chains | 1 |
| Total formula weight | 18291.85 |
| Authors | Nissink, J.W.M.,Bista, M.,Breed, J.,Carter, N.,Embrey, K.,Read, J.,Phillips, C.,Winter, J.J. (deposition date: 2016-01-06, release date: 2016-07-20, Last modification date: 2017-01-25) |
| Primary citation | Nissink, J.W.M.,Bista, M.,Breed, J.,Carter, N.,Embrey, K.,Read, J.,Winter-Holt, J.J. Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11:51154-, 2016 Cited by PubMed: 26999531DOI: 10.1371/JOURNAL.PONE.0151154 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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