PDB: 66212 件ウェブページステータス検索Chemie searchBIRD

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8TOQ	ACE2-peptide 1 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... 著者 Christie, M, Payne, R.J. 登録日 2023-08-03 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024
8TOS	ACE2-peptide 6 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... 著者 Christie, M, Payne, R. 登録日 2023-08-03 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024
8TOR	ACE2-peptide 2 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Christie, M, Payne, R.J. 登録日 2023-08-03 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024
8TOT	ACE2-peptide2 complex crystal form 2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... 著者 Christie, M, Payne, R.J. 登録日 2023-08-03 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024
8TOU	ACE2-peptide 2 complex crystal form 3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... 著者 Franck, C, Payne, R.J, Christie, M. 登録日 2023-08-04 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024
6CT6	Crystal structure of lactate dehydrogenase from Eimeria maxima with NADH and oxamate 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Lactate dehydrogenase, OXAMIC ACID, ... 著者 Wirth, J.D, Xu, C, Theobald, D.L. 登録日 2018-03-22 公開日 2019-03-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.705 Å) 主引用文献 The Mechanistic, Structural, and Evolutionary Origin of Lactate Dehydrogenase Substrate Specificity in Apicomplexa To Be Published
7TO9	BRD3-BD1 in complex with RaPID linear peptide 2xAcK.4xE (diAcK.4xE) 分子名称: 2xAcK.4xE (diAcK.4xE), Bromodomain-containing protein 3, GLYCEROL 著者 Mackay, J.P, Low, J.K.K, Patel, K. 登録日 2022-01-23 公開日 2023-01-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome. J.Biol.Chem., 299, 2023
7TO8	BRD3-BD1 in complex with RaPID linear peptide 2xAcK.1 (diAcK.1) 分子名称: 2xAcK.1 (diAcK.1), Bromodomain-containing protein 3, GLYCEROL 著者 Patel, K, Low, J.K.K, Mackay, J.P. 登録日 2022-01-23 公開日 2023-01-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome. J.Biol.Chem., 299, 2023
7TOA	BRD3-BD1 in complex with RaPID linear peptide 3xAcK.1 (triAcK.1) 分子名称: 3xAcK.1 (triAcK.1), Bromodomain-containing protein 3, GLYCEROL 著者 Patel, K, Low, J.K.K, Mackay, J.P. 登録日 2022-01-23 公開日 2023-01-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome. J.Biol.Chem., 299, 2023
6JDJ	Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 分子名称: AcrIIC2, CRISPR-associated endonuclease Cas9 著者 Cheng, Z, Huang, X, Sun, W, Wang, Y. 登録日 2019-02-01 公開日 2019-05-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2. Nat Commun, 10, 2019
7TO7	BRD3-BD1 in complex with RaPID linear peptide 1xAcK.4XE (monoAcK.4xE) 分子名称: 1xAcK.4xE (monoAcK.4xE), Bromodomain-containing protein 3, GLYCEROL 著者 Mackay, J.P, Low, J.K.K, Patel, K. 登録日 2022-01-23 公開日 2023-01-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome. J.Biol.Chem., 299, 2023
4IXC	Crystal structure of Human Glucokinase in complex with a small molecule activator. 分子名称: (2S)-2-{[1-(3-chloropyridin-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy}-N-(5-methylpyridin-2-yl)-3-(propan-2-yloxy)propanamide, Glucokinase isoform 3, SODIUM ION, ... 著者 Ogg, D.J, Hargreaves, D, Gerhardt, S. 登録日 2013-01-25 公開日 2013-04-24 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Matched triplicate design sets in the optimisation of glucokinase activators maximising medicinal chemistry information content To be Published
7UNX	NMR solution structure of xanthusin-1 分子名称: Xanthusin-1 著者 Harvey, P.J, Craik, D.J. 登録日 2022-04-12 公開日 2023-04-19 実験手法 SOLUTION NMR 主引用文献 Discovery of five classes of bacterial defensins: ancestral precursors of defensins from Eukarya? To Be Published
4L7S	Kinase domain mutant of human Itk in complex with an aminobenzothiazole inhibitor 分子名称: SULFATE ION, Tyrosine-protein kinase ITK/TSK, trans-4-({4-[difluoro(4-fluorophenyl)methyl]-6-[(5-methoxy[1,3]thiazolo[5,4-b]pyridin-2-yl)amino]pyrimidin-2-yl}amino)cyclohexanol 著者 Somers, D.O. 登録日 2013-06-14 公開日 2014-01-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy. ACS Med Chem Lett, 4, 2013
6JDX	Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 preprocessed with protease alpha-Chymotrypsin 分子名称: 1,2-ETHANEDIOL, AcrIIC2, CRISPR-associated endonuclease Cas9 著者 Cheng, Z, Huang, X, Sun, W, Wang, Y. 登録日 2019-02-02 公開日 2019-05-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2. Nat Commun, 10, 2019
6MNZ	Crystal structure of RibBX, a two domain 3,4-dihydroxy-2-butanone 4-phosphate synthase from A. baumannii. 分子名称: 3,4-dihydroxy-2-butanone 4-phosphate synthase, CHLORIDE ION, SULFATE ION 著者 Wang, J, Gonzalez-Gutierrez, G, Giedroc, D.P. 登録日 2018-10-03 公開日 2019-04-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Multi-metal Restriction by Calprotectin Impacts De Novo Flavin Biosynthesis in Acinetobacter baumannii. Cell Chem Biol, 26, 2019
1GH9	SOLUTION STRUCTURE OF A 8.3 KDA PROTEIN (GENE MTH1184) FROM METHANOBACTERIUM THERMOAUTOTROPHICUM 分子名称: 8.3 KDA PROTEIN (GENE MTH1184) 著者 Kozlov, G, Ekiel, I, Gehring, K, Northeast Structural Genomics Consortium (NESG) 登録日 2000-11-30 公開日 2000-12-11 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Structural proteomics of an archaeon. Nat.Struct.Biol., 7, 2000
2M7A	Enteropathogenic Escherichia coli 0111:H- str. 11128 ORF EC0111_1119 similar to bacteriophage lambda ea8.5 分子名称: Uncharacterized protein, ZINC ION 著者 Donaldson, L.W.F. 登録日 2013-04-18 公開日 2013-06-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 The Solution Structures of Two Prophage Homologues of the Bacteriophage lambda Ea8.5 Protein Reveal a Newly Discovered Hybrid Homeodomain/Zinc-Finger Fold. Biochemistry, 52, 2013
2CTI	DETERMINATION OF THE COMPLETE THREE-DIMENSIONAL STRUCTURE OF THE TRYPSIN INHIBITOR FROM SQUASH SEEDS IN AQUEOUS SOLUTION BY NUCLEAR MAGNETIC RESONANCE AND A COMBINATION OF DISTANCE GEOMETRY AND DYNAMICAL SIMULATED ANNEALING 分子名称: TRYPSIN INHIBITOR 著者 Holak, T.A, Gondol, D, Otlewski, J, Wilusz, T. 登録日 1990-08-28 公開日 1992-01-15 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Determination of the complete three-dimensional structure of the trypsin inhibitor from squash seeds in aqueous solution by nuclear magnetic resonance and a combination of distance geometry and dynamical simulated annealing. J.Mol.Biol., 210, 1989
2M7B	ORF PP_3909 from Pseudomonas putida KT2440 encoding a protein similar to bacteriophage lambda ea8.5 分子名称: ZINC ION, uncharacterized protein 著者 Donaldson, L.W.F. 登録日 2013-04-18 公開日 2013-06-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 The Solution Structures of Two Prophage Homologues of the Bacteriophage lambda Ea8.5 Protein Reveal a Newly Discovered Hybrid Homeodomain/Zinc-Finger Fold. Biochemistry, 52, 2013
5JPL	LP2006, a handcuff-topology lasso peptide antibiotic 分子名称: Uncharacterized protein 著者 Tietz, J.I, Schwalen, C.J, Blair, P.M, Zakai, U.I, Mitchell, D.A. 登録日 2016-05-03 公開日 2017-03-01 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 A new genome-mining tool redefines the lasso peptide biosynthetic landscape. Nat. Chem. Biol., 13, 2017
5IDZ	Structure of Human Enolase 2 in complex with (S)-(1-hydroxy-2-oxopiperidin-3-yl)phosphonate 分子名称: Gamma-enolase, MAGNESIUM ION, TRIETHYLENE GLYCOL, ... 著者 Leonard, P.G, Muller, F.L. 登録日 2016-02-24 公開日 2017-02-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Pomhex, a cell-permeable Enolase inhibitor for Collateral Lethality targeting of ENO1-deleted Glioblastoma To Be Published
7B5K	E. coli 70S containing suppressor tRNA in the A-site stabilized by a Negamycin analogue and P-site tRNA-nascent chain. 分子名称: 16S rRNA, 2-[[[(3~{R},5~{R})-3-azanyl-6-(3-azanylpropylamino)-5-oxidanyl-hexanoyl]amino]-methyl-amino]ethanoic acid, 23S rRNA, ... 著者 Albers, S, Beckert, B, Matthies, M, Schuster, R, Riedner, M, Seuring, C, Sanyal, S, Torda, A, Wilson, N.D, Ignatova, Z. 登録日 2020-12-03 公開日 2021-05-26 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Harnessing evolutionarily flexibility in tRNAs to maximize nonsense suppression activities Nat Commun, 2021
5GSQ	Crystal structure of IgG Fc with a homogeneous glycoform and Antibody-Dependent Cellular Cytotoxicity 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chen, C.-L, Hsu, J.-C, Lin, C.-W, Wu, C.-Y, Wong, C.-H, Ma, C. 登録日 2016-08-17 公開日 2017-06-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of a Homogeneous IgG-Fc Glycoform with the N-Glycan Designed to Maximize the Antibody Dependent Cellular Cytotoxicity ACS Chem. Biol., 12, 2017
5H5O	A cyclic-GMP-dependent signalling pathway regulates bacterial phytopathogenesis 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, Diguanylate cyclase 著者 Chin, K.H, Chou, S.-H. 登録日 2016-11-08 公開日 2017-05-24 実験手法 X-RAY DIFFRACTION (2.122 Å) 主引用文献 A cyclic GMP-dependent signalling pathway regulates bacterial phytopathogenesis EMBO J., 32, 2013

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