8TOT

ACE2-peptide2 complex crystal form 2

Summary for 8TOT

• Entry DOI: 10.2210/pdb8tot/pdb
• Related: 8TOQ 8TOR 8TOS
• Descriptor: Angiotensin-converting enzyme 2, Cyclic peptide 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: peptidase, enzyme, sars-cov-2, angiotensin, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 152454.06

Authors

Christie, M.,Payne, R.J. (deposition date: 2023-08-03, release date: 2024-02-07)

• Primary citation: Bedding, M.J.,Franck, C.,Johansen-Leete, J.,Aggarwal, A.,Maxwell, J.W.C.,Patel, K.,Hawkins, P.M.E.,Low, J.K.K.,Siddiquee, R.,Sani, H.M.,Ford, D.J.,Turville, S.,Mackay, J.P.,Passioura, T.,Christie, M.,Payne, R.J.; Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.; Acs Chem.Biol., 19:141-152, 2024; PubMed: 38085789; DOI: 10.1021/acschembio.3c00568

Experimental method

X-RAY DIFFRACTION (2.8 Å)