6ZWK
Crystal structure of the phosphorylated C-terminal tail of histone H2AX in complex with a specific nanobody (C6 gammaXbody)
Summary for 6ZWK
Entry DOI | 10.2210/pdb6zwk/pdb |
Descriptor | gammaXbody, Histone H2AX, SODIUM ION, ... (5 entities in total) |
Functional Keywords | nanobody, phosphopeptide-recognition protein, gamma-h2ax, immune system |
Biological source | Vicugna pacos (alpaca) More |
Total number of polymer chains | 12 |
Total formula weight | 106914.98 |
Authors | McEwen, A.G.,Moeglin, E.,Desplancq, D.,Weiss, E.,Poterszman, A. (deposition date: 2020-07-28, release date: 2021-07-21, Last modification date: 2024-01-31) |
Primary citation | Moeglin, E.,Desplancq, D.,Stoessel, A.,Massute, C.,Ranniger, J.,McEwen, A.G.,Zeder-Lutz, G.,Oulad-Abdelghani, M.,Chiper, M.,Lafaye, P.,Di Ventura, B.,Didier, P.,Poterszman, A.,Weiss, E. A Novel Nanobody Precisely Visualizes Phosphorylated Histone H2AX in Living Cancer Cells under Drug-Induced Replication Stress. Cancers (Basel), 13:-, 2021 Cited by PubMed: 34282773DOI: 10.3390/cancers13133317 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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