6ZWK
Crystal structure of the phosphorylated C-terminal tail of histone H2AX in complex with a specific nanobody (C6 gammaXbody)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | gammaXbody | polymer | 150 | 16577.2 | 6 | Vicugna pacos (alpaca) | ||
| 2 | G, H, I, J, K... (G, H, I, J, K...) | Histone H2AX | polymer | 10 | 1209.2 | 6 | UniProt (P16104) | Homo sapiens | H2a/x,Histone H2A.X |
| 3 | M, N, O, P, R... (A, B, C, D, E...) | SODIUM ION | non-polymer | 23.0 | 7 | Chemie (NA) | |||
| 4 | Q (D) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | AA, BA, CA, DA, EA... (G, H, I, J, K...) | water | water | 18.0 | 980 | Chemie (HOH) |
Sequence modifications
G, H, I, J, K, L: 133 - 142 (UniProt: P16104)
| PDB | External Database | Details |
|---|---|---|
| Cys 133 | Lys 134 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 106718.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 196.4 | |
| All* | Total formula weight | 106915.0 |
