2P6R
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6EYA
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6FIJ
| Structure of the loading/condensing region (SAT-KS-MAT) of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, ... | 著者 | Herbst, D.A, Jakob, R.P, Townsend, C.A, Maier, T. | 登録日 | 2018-01-18 | 公開日 | 2018-03-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | The structural organization of substrate loading in iterative polyketide synthases. Nat. Chem. Biol., 14, 2018
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6EYB
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6F1N
| Estimation of relative drug-target residence times by random acceleration molecular dynamics simulation | 分子名称: | 4-[5-[2-aminocarbonyl-3,6-bis(azanyl)-5-cyano-thieno[2,3-b]pyridin-4-yl]-2-methoxy-phenoxy]butanoic acid, Heat shock protein HSP 90-alpha, SULFATE ION | 著者 | Musil, D, Lehmann, M, Eggenweiler, H.-M. | 登録日 | 2017-11-22 | 公開日 | 2018-05-30 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Estimation of Drug-Target Residence Times by tau-Random Acceleration Molecular Dynamics Simulations. J Chem Theory Comput, 14, 2018
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2OX2
| Structure of the cantionic, antimicrobial hexapeptide cyclo(RRWWFR) bound to DPC-micelles | 分子名称: | cRW2 peptide | 著者 | Appelt, C, Wessolowski, A, Soderhall, J.A, Dathe, M, Schmieder, P. | 登録日 | 2007-02-19 | 公開日 | 2007-12-25 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures of cyclic, antimicrobial peptides in a membrane-mimicking environment define requirements for activity. J.Pept.Sci., 14, 2007
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2PE8
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2MPS
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2LQ4
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2P6U
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2PQW
| Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 17-25), trigonal form | 分子名称: | ACETATE ION, Histone H4, Lethal(3)malignant brain tumor-like protein | 著者 | Allali-Hassani, A, Liu, Y, Herzanych, N, Ouyang, H, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J.R, Structural Genomics Consortium (SGC) | 登録日 | 2007-05-02 | 公開日 | 2007-07-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | L3MBTL1 recognition of mono- and dimethylated histones. Nat.Struct.Mol.Biol., 14, 2007
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2POH
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2Q2T
| Structure of Chlorella virus DNA ligase-adenylate bound to a 5' phosphorylated nick | 分子名称: | 5'-D(*AP*TP*TP*GP*CP*GP*AP*CP*(OMC)P*C)-3', 5'-D(*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*T)-3', 5'-D(P*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*A)-3', ... | 著者 | Lima, C.D, Nandakumar, J, Nair, P.A, Smith, P, Shuman, S. | 登録日 | 2007-05-29 | 公開日 | 2007-07-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for nick recognition by a minimal pluripotent DNA ligase. Nat.Struct.Mol.Biol., 14, 2007
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2PZ1
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2M08
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2PP4
| Solution Structure of ETO-TAFH refined in explicit solvent | 分子名称: | Protein ETO | 著者 | Wei, Y, Liu, S, Lausen, J, Woodrell, C, Cho, S, Biris, N, Kobayashi, N, Yokoyama, S, Werner, M.H. | 登録日 | 2007-04-27 | 公開日 | 2007-06-19 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription Nat.Struct.Mol.Biol., 14, 2007
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2PX6
| Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat | 分子名称: | (2S,3S,5S)-5-[(N-FORMYL-L-LEUCYL)OXY]-2-HEXYL-3-HYDROXYHEXADECANOIC ACID, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Thioesterase domain | 著者 | Pemble IV, C.W, Johnson, L.C, Kridel, S.J, Lowther, W.T. | 登録日 | 2007-05-14 | 公開日 | 2007-07-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat. Nat.Struct.Mol.Biol., 14, 2007
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2PKG
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2Q2U
| Structure of Chlorella virus DNA ligase-product DNA complex | 分子名称: | 5'-D(*AP*TP*TP*GP*CP*GP*AP*CP*(OMC)P*CP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*A)-3', 5'-D(*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*T)-3', Chlorella virus DNA ligase | 著者 | Lima, C.D, Nandakumar, J, Nair, P.A, Smith, P, Shuman, S. | 登録日 | 2007-05-29 | 公開日 | 2007-07-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for nick recognition by a minimal pluripotent DNA ligase. Nat.Struct.Mol.Biol., 14, 2007
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2Q6J
| Crystal Structure of Estrogen Receptor alpha Complexed to a B-N Substituted Ligand | 分子名称: | 4-[(DIMESITYLBORYL)(2,2,2-TRIFLUOROETHYL)AMINO]PHENOL, Estrogen receptor, GRIP peptide | 著者 | Zhou, H, Nettles, K.W, Bruning, J.B, Kim, Y, Joachimiak, A, Sharma, S, Carlson, K.E, Stossi, F, Katzenellenbogen, B.S, Greene, G.L, Katzenellenbogen, J.A. | 登録日 | 2007-06-05 | 公開日 | 2007-06-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands Chem.Biol., 14, 2007
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2Q2E
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8TDM
| Cryo-EM structure of AtMSL10-K539E | 分子名称: | Mechanosensitive ion channel protein 10 | 著者 | Zhang, J, Yuan, P. | 登録日 | 2023-07-03 | 公開日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Open structure and gating of the Arabidopsis mechanosensitive ion channel MSL10. Nat Commun, 14, 2023
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8TB7
| Cryo-EM Structure of GPR61- | 分子名称: | 6-{[(3,5-difluoropyridin-4-yl)methyl]amino}-N-(4-ethoxy-6-methylpyrimidin-2-yl)-2-methoxy-N-(2-methoxyethyl)pyridine-3-sulfonamide, Fab hinge-binding nanobody, Fab24 BAK5 heavy chain, ... | 著者 | Lees, J.A, Dias, J.M, Han, S. | 登録日 | 2023-06-28 | 公開日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | An inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism. Nat Commun, 14, 2023
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8U3M
| The FARFAR-MD-NMR ensemble of an HIV-1 TAR excited state | 分子名称: | The excited state of HIV-1 transactivation response element (31-MER) | 著者 | Geng, A, Ganser, L, Roy, R, Shi, H, Pratihar, S, Case, D.A, Al-Hashimi, H.M. | 登録日 | 2023-09-07 | 公開日 | 2023-10-04 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | An RNA excited conformational state at atomic resolution. Nat Commun, 14, 2023
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8TB0
| Cryo-EM Structure of GPR61-G protein complex stabilized by scFv16 | 分子名称: | GPR61 fused to dominant negative G alpha S/I N18 chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Lees, J.A, Dias, J.M, Han, S. | 登録日 | 2023-06-28 | 公開日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | An inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism. Nat Commun, 14, 2023
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