Structure of complex of MDM2(3-109) and P73 TAD(10-25)

Summary for 2MPS

DescriptorE3 ubiquitin-protein ligase Mdm2, Tumor protein p73 (2 entities in total)
Functional Keywordsmdm2, p73 tad, p53, ligase-peptide complex, ligase/peptide
Biological sourceHomo sapiens (human)
Cellular locationNucleus, nucleoplasm Q00987
Nucleus O15350
Total number of polymer chains2
Total molecular weight14067.1
Shin, J.S.,Ha, J.H.,Chi, S.W. (deposition date: 2014-06-02, release date: 2015-06-03)
Primary citation
Shin, J.S.,Ha, J.H.,Lee, D.H.,Ryu, K.S.,Bae, K.H.,Park, B.C.,Park, S.G.,Yi, G.S.,Chi, S.W.
Structural convergence of unstructured p53 family transactivation domains in MDM2 recognition
Cell Cycle, 14:533-543, 2015
PubMed: 25591003 (PDB entries with the same primary citation)
DOI: 10.1080/15384101.2014.998056
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers60.9%4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures