PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

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6PJJ	Human PRPF4B bound to benzothiophene inhibitor 224 分子名称: 1,2-ETHANEDIOL, 4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, PHOSPHATE ION, ... 著者 Godoi, P.H.C, Santiago, A.S, Fala, A.M, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) 登録日 2019-06-28 公開日 2019-08-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 to be published To Be Published
6ATW	Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox 分子名称: Chlorotoxin 著者 Gewe, M.M, Rupert, P, Strong, R.K. 登録日 2017-08-29 公開日 2018-02-28 最終更新日 2018-03-14 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25, 2018
6Y33	Streptavidin mutant S112R with a biotC5-1 cofactor - an artificial iron hydroxylase 分子名称: GLYCEROL, Streptavidin, biotC5-1 cofactor 著者 Serrano-Plana, J, Rumo, C, Rebelein, J.G, Peterson, R.L, Barnet, M, Ward, T.R. 登録日 2020-02-17 公開日 2020-07-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Enantioselective Hydroxylation of Benzylic C(sp3)-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology. J.Am.Chem.Soc., 142, 2020
5K60	Crystal structure of N-terminal amidase with Gln-Val peptide 分子名称: GLUTAMINE, Nta1p, VALINE 著者 Kim, M.K, Oh, S.-J, Lee, B.-G, Song, H.K. 登録日 2016-05-24 公開日 2017-01-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5KDU	ZmpB metallopeptidase in complex with a2,6-Sialyl T-antigen 分子名称: 1,2-ETHANEDIOL, F5/8 type C domain protein, SERINE, ... 著者 Noach, I, Ficko-Blean, E, Stuart, C, Boraston, A.B. 登録日 2016-06-08 公開日 2017-01-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Recognition of protein-linked glycans as a determinant of peptidase activity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6PJQ	Time-resolved structural snapshot of proteolysis by GlpG inside the membrane 分子名称: Peptide aldehyde inhibitor, Rhomboid protease GlpG 著者 Urban, S, Cho, S. 登録日 2019-06-28 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019
6EV0	The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (AC129) 分子名称: ISOPROPYL ALCOHOL, Listeriolysin regulatory protein, [(3~{R})-3-carboxy-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridin-8-yl]-dimethyl-azanium, ... 著者 Begum, A, Hall, M, Grundstrom, C, Cairns, A.G, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. 登録日 2017-10-31 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J. Med. Chem., 61, 2018
6P7Q	Structure of E. coli MS115-1 NucC, 5'-pApA bound form 分子名称: CHLORIDE ION, E. coli MS115-1 NucC, RNA (5'-R(P*AP*A)-3') 著者 Ye, Q, Lau, R.K, Berg, K.R, Corbett, K.D. 登録日 2019-06-06 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity. Mol.Cell, 77, 2020
6F6K	R2-like ligand-binding oxidase V72L mutant with anaerobically reconstituted Mn/Fe cofactor 分子名称: FE (II) ION, LAURIC ACID, MANGANESE (II) ION, ... 著者 Griese, J.J, Hogbom, M. 登録日 2017-12-05 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.982 Å) 主引用文献 Ether cross-link formation in the R2-like ligand-binding oxidase. J. Biol. Inorg. Chem., 23, 2018
6Y0K	Sulfite oxidase from Thermus thermophilus with coordinated phosphate 分子名称: (MOLYBDOPTERIN-S,S)-OXO-MOLYBDENUM, GLYCEROL, PHOSPHATE ION, ... 著者 Djeghader, A, Soulimane, T. 登録日 2020-02-08 公開日 2020-08-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural evidence for a reaction intermediate mimic in the active site of a sulfite dehydrogenase. Chem.Commun.(Camb.), 56, 2020
6P9R	E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 6 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
8V5A	Prefusion-stabilized Respirovirus type 3 Fusion protein 分子名称: Camelid nanobody 4C06, Fusion glycoprotein F0 著者 Johnson, N.V, McLellan, J.S. 登録日 2023-11-30 公開日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein. Nat Commun, 15, 2024
6F35	Crystal structure of the aspartate aminotranferase from Rhizobium meliloti 分子名称: ACETATE ION, Aspartate aminotransferase B, GLYCEROL, ... 著者 Cobessi, D, Graindorge, M, Giustini, C, Matringe, M. 登録日 2017-11-28 公開日 2019-03-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1 beta aspartate aminotransferase. Febs J., 286, 2019
5JU9	Structure of a beta-1,4-mannanase, SsGH134, in complex with Man3. 分子名称: CHLORIDE ION, beta-1,4-mannanase, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose 著者 Jin, Y, Petricevic, M, Goddard-Borger, E.D, Williams, S.J, Davies, G.J. 登録日 2016-05-10 公開日 2016-11-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 A beta-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism. ACS Cent Sci, 2, 2016
6F6H	R2-like ligand-binding oxidase V72L mutant with aerobically reconstituted Mn/Fe cofactor 分子名称: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ... 著者 Griese, J.J, Hogbom, M. 登録日 2017-12-05 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.764 Å) 主引用文献 Ether cross-link formation in the R2-like ligand-binding oxidase. J. Biol. Inorg. Chem., 23, 2018
6P9P	E.coli LpxA in complex with Compound 1 分子名称: 3-[2-(4-methoxyphenyl)-2-oxoethyl]-5,5-diphenylimidazolidine-2,4-dione, Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
6F6M	R2-like ligand-binding oxidase Y162F mutant with anaerobically reconstituted Mn/Fe cofactor 分子名称: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ... 著者 Griese, J.J, Hogbom, M. 登録日 2017-12-05 公開日 2018-12-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.393 Å) 主引用文献 Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase. J. Biol. Inorg. Chem., 24, 2019
6PGY	MTSL labelled T4 lysozyme pseudo-wild type K65C mutant 分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Endolysin, ... 著者 Cuneo, M.J, Myles, D.A, Li, L. 登録日 2019-06-25 公開日 2020-07-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Making hydrogens stand out: Enhanced neutron diffraction from biological crystals using dynamic nuclear polarization To be published
5K66	Crystal structure of N-terminal amidase with Asn-Glu peptide 分子名称: ASPARAGINE, GLUTAMIC ACID, Nta1p 著者 Kim, M.K, Oh, S.-J, Lee, B.-G, Song, H.K. 登録日 2016-05-24 公開日 2017-01-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
6EWG	Oreochromis niloticus CEP120 second C2 domain (C2B) 分子名称: Centrosomal protein 120 著者 van Breugel, M. 登録日 2017-11-04 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis. Cell Rep, 23, 2018
2LED	Unique structural features of interconverting monomeric and dimeric G-quadruplexes adopted by a sequence from intron of N-myc gene 分子名称: DNA (5'-D(*TP*AP*GP*GP*GP*CP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*A)-3') 著者 Trajkovski, M, Plavec, J, Webba da Silva, M. 登録日 2011-06-15 公開日 2012-03-14 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Unique Structural Features of Interconverting Monomeric and Dimeric G-Quadruplexes Adopted by a Sequence from the Intron of the N-myc Gene. J.Am.Chem.Soc., 134, 2012
6B7O	Crystal structure of Legionella effector sdeD (lpg2509) H67A in complex with ADP-ribosylated Ubiquitin 分子名称: Polyubiquitin-C, SdeD (lpg2509) H67A, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE 著者 Mao, Y, Akturk, A, Wasilko, J. 登録日 2017-10-04 公開日 2018-04-18 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector. Nature, 557, 2018
7ZRB	Crystal structure of Beta-catenin Armadillo repeats domain in complex with the inhibitor RS6452 分子名称: 4-bromanyl-~{N}-(3-pyridin-2-ylphenyl)benzenesulfonamide, Catenin beta-1 著者 Capelli, D, Pochetti, G, Montanari, R. 登録日 2022-05-04 公開日 2023-05-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.434 Å) 主引用文献 Novel N -(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the beta-Catenin Armadillo Repeats Domain as an Anticancer Agent. Acs Pharmacol Transl Sci, 6, 2023
6YOX	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-027 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2020-04-15 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59, 2020
6PH0	T4 lysozyme pseudo-wild type soaked in TEMPO 分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Endolysin 著者 Cuneo, M.J, Myles, D.A, Li, L. 登録日 2019-06-25 公開日 2020-07-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.947 Å) 主引用文献 Making hydrogens stand out: Enhanced neutron diffraction from biological crystals using dynamic nuclear polarization To be published

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